STUDY GUIDE- McCance & Huether’s Pathophysiology: The Biological Basis for Illness in Adults and Children (9th Edition,2024),,,Julia L. Rogers.

Study Guide for
McCance & Huether’s Pathophysiology: The
Biological Basis for Illness in Adults and
Children 9th Edition

, Contents
PART ONE BASIC CONCEPTS OF PATHOPHYSIOLOGY
Unit 1 The Cell
1. Cellular Biology, 1
2. Genes and Genetic Illnesss, 5
3. Altered Cellular and Tissue Biology, 11
4. Fluids and Electrolytes, Acids and Bases, 17

Unit 2 Mechanisms of Self-Defense
5. Innate Immunity: Inflammation and Wound Healing, 25
6. Third Line of Defense: Adaptive Immunity, 33
7. Infection and Defects in Mechanisms of Defense, 39
8. Stress and Illness, 47

Unit 3 Cellular Proliferation: Cancer
9. Biology, Clinical Manifestations, and Treatment of Cancer, 53
10. Cancer Epidemiology, 63
11. Cancer in Kids, 69


PART TWO BODY SYSTEMS AND ILLNESSS
Unit 4 The Neurologic System
12. Structure and Function of the Neurologic System, 73
13. Pain, Temperature, Sleep, and Sensory Function, 77
14. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function, 85
15. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction, 95
16. Alterations of Neurologic Function in Kids, 107

Unit 5 The Endocrine System
17. Mechanisms of Hormonal Regulation, 113
18. Alterations of Hormonal Regulation, 117

Unit 6 The Hematologic System
19. Structure and Function of the Hematologic System, 131
20. Alterations of Hematologic Function, 135
21. Alterations of Hematologic Function in Kids, 147

Unit 7 The Cardiovascular and Lymphatic Systems
22. Structure and Function of the Cardiovascular and Lymphatic Systems, 153
23. Alterations of Cardiovascular Function, 157
24. Alterations of Cardiovascular Function in Kids, 177

Unit 8 The Pulmonary System
25. Structure and Function of the Pulmonary System, 183
26. Alterations of Pulmonary Function, 187
27. Alterations of Pulmonary Function in Kids, 199



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Contents

,Unit 9 The Renal and Urologic Systems
28. Structure and Function of the Renal and Urologic Systems, 205
29. Alterations of Renal and Urinary Tract Function, 209
30. Alterations of Renal and Urinary Tract Function in Kids, 219

Unit 10 The Reproductive Systems
31. Structure and Function of the Reproductive Systems, 225
32. Alterations of the Reproductive Systems, Including Sexually Transmitted Infections, 229

Unit 11 The Digestive System
33. Structure and Function of the Digestive System, 243
34. Alterations of Digestive Function, 247
35. Alterations of Digestive Function in Kids, 261

Unit 12 The Musculoskeletal and Integumentary Systems
36. Structure and Function of the Musculoskeletal System, 267
37. Alterations of Musculoskeletal Function, 271
38. Alterations of Musculoskeletal Function in Kids, 285
39. Structure, Function, and Disorders of the Integument, 291
40. Alterations of the Integument in Kids, 303

Answers to Practice Examinations, 309




x
Contents

, SECTION ONE UNITE TITLE OR SECTION TITLE




Cellular Biology

FOUNDATIONAL OBJECTIVES 10. Identify the phases of mitosis and cytokinesis.
After reviewing this chapter, the learner will be able to Review pages 22-23; refer to Figure 1-26.
do the following:
11. Describe the stimulation of cell proliferation by
1. State the functions of a typical eukaryotic cell. growth factors.
Review pages 2-3. Review pages 23-24; refer to Figure 1-27 and Table 1-5.

2. Describe the structure and function of the nucleus 12. Characterize pattern formation.
and identify the cytoplasmic organelles. Review page 24.
Review page 3; refer to Figures 1-1 and 1-2 and
Table 1-1. 13. Identify the location and a major function for
each type of tissue: epithelial, connective, muscle,
3. Describe the structure and function of the plasma and nervous.
membrane. Refer to Boxes 1-3 through 1-5.
Review pages 3 and 5-7; refer to Figures 1-3 through
1-5 and Tables 1-2 and 1-3. PRACTICE EXAMINATION

4. Describe cellular receptors. Multiple Choice
Review pages 7-8; refer to Figure 1-6. Circle the correct answer for each question:

5. Identify the three mechanisms that bind cells 1. Which are principal parts of a eukaryotic cell?
together. a. fat, carbohydrate, and protein
b. minerals and water
Review pages 8-9; refer to Figures 1-7 and 1-8. c. organelles
d. phospholipids and protein
6. Describe the primary modes of chemical signaling. e. protoplasm and nucleus
Review pages 9, 11, and 13 refer to Figures 1-9
through 1-12 and Table 1-3. 2. The cell membrane is described as a fluid mosaic.
Some proteins have a degree of mobility within the
lipid bilayer. (More than one answer may be
7. Describe cellular catabolism and the transfer of
correct.)
energy to accomplish other cellular processes.
a. The first sentence is true.
Refer to Figures 1-13 through 1-15. b. The first sentence is false.
c. The second sentence is true.
8. Differentiate between passive and active d. The second sentence is false.
transport, between endocytosis and exocytosis, e. The second sentence is relevant to the first.
and between phagocytosis and pinocytosis. f. The second sentence is irrelevant to the first.
Refer to Figures 1-16 through 1-24 and Table 1-4.

9. Describe the changes in the plasma membrane
that result in an action potential.
Review pages 21-22; refer to Figure 1-25.
1
Copyright © 2012, 2008, 2004, 2000, 1996 by Mosby, an imprint of Elsevier Inc. All rights reserved. Chapter 1 Cellular Biology