BCH210 Section 2 Questions With Complete Solutions

BCH210 Section 2 Questions
With Complete Solutions
Direction of phospholipid movement in flippases? correct
answer: Outer to inner leaflet
Moves PE (neutral) and PS (-1)

Direction of phospholipid movement in floppases? correct
answer: Inner to outer leaflet

Function of Scramblase correct answer: Increases membrane
SYMMETRY

Moves phospholipids down their conc gradient

Result of adding crosslinkers into cell membrane for FRAP
correct answer: Slows down diffusion of phospholipids; slower
recovery rate

Entropy of lipids [?] when lipids aggregate in water. correct
answer: Decrease. More ordered lipids.

Entropy of water [?] when lipids aggregate in water. correct
answer: Increase. Lipid aggregation displaces water molecules.

Essential Fatty Acids correct answer: Omega 3 and 6 fatty acids

, Double bonds on terminal ends of FA are hard to synthesize by
body

Tri-acyl-glycerols (TAGs) correct answer: Three fatty acids
(ester) bonded to glycerol

GLYCEROPHOSPHOLIPIDS correct answer: FA on C1 & C2,
phosphate on C3
polar head grps attach to phosp. head

Where are PE and PS located on leaflet correct answer:
Cytosolic

SPHINGOLIPIDS correct answer: Sphingosine backbone + FA
on C2 (via amide bonds)
Diff head groups attach on C1, no C3.

Cerebrosides correct answer: Type of sphingolipid
FA on C2, SINGLE sugar on C1

Ceramides correct answer: Type of sphingolipid
FA on C2, any head group on C1

Lipid Raft formation correct answer: Cholesterol, sphingolipids,
glycolipids, & lipid anchored prot form complexes tgt

Signature Seq of amphipathic helix correct answer: Alternating
2 P and 2 NP AAs
Ex: P-P-NP-NP-P-P-NP-NP-etc etc