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Exam (elaborations)

Immunologic Disorders

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1. What is responsible for initiating the inflammatory response in addition to immunoglobulin E (IgE)? a. Eosinophils b. Lymphocytes c. Basophils d. Neutrophils - ANS: C Basophils initiate a massive inflammatory response with histamine that quickly brings other white blood cells (WBCs) to the site of an infection. DIF: Cognitive Level: Knowledge REF: p. 643 OBJ: 1 TOP: Components of the Immune System KEY: Nursing Process Step: Implementation 2. Where are histamine-releasing mast cells located? a. Circulating in the blood b. Circulating in the lymph c. Attached to organ tissue d. Embedded in the bone marrow - ANS: C Mast cells are located in organ tissue when they release their histamine. The organ to which they are attached is the host of the inflammatory response. If the organ is the lung, the response may be asthma; if the organ is the colon, the response may be diarrhea. DIF: Cognitive Level: Knowledge REF: p. 643 OBJ: 1 TOP: Mast Cells KEY: Nursing Process Step: Assessment 3. What is true concerning passive-acquired immunity? a. Antibodies are acquired from outside the host and instilled in the host.

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Immunologic Disorders Exam (correct answers A+)


1. What is responsible for initiating the inflammatory response in addition to immunoglobulin E (IgE)?

a. Eosinophils

b. Lymphocytes

c. Basophils

d. Neutrophils - ANS: C

Basophils initiate a massive inflammatory response with histamine that quickly brings other white blood
cells (WBCs) to the site of an infection.



DIF: Cognitive Level: Knowledge REF: p. 643 OBJ: 1

TOP: Components of the Immune System

KEY: Nursing Process Step: Implementation



2. Where are histamine-releasing mast cells located?

a. Circulating in the blood

b. Circulating in the lymph

c. Attached to organ tissue

d. Embedded in the bone marrow - ANS: C

Mast cells are located in organ tissue when they release their histamine. The organ to which they are
attached is the host of the inflammatory response. If the organ is the lung, the response may be asthma;
if the organ is the colon, the response may be diarrhea.



DIF: Cognitive Level: Knowledge REF: p. 643 OBJ: 1

TOP: Mast Cells KEY: Nursing Process Step: Assessment



3. What is true concerning passive-acquired immunity?

a. Antibodies are acquired from outside the host and instilled in the host.

, b. Antibodies are manufactured in response to a disease in the host.

c. Antibodies are innately acquired because of being born a human being.

d. Antibodies are cell mediated inside the host. - ANS: A

Gamma globulin injections provide passive-acquired immunity. The antibodies that are injected have
been produced by another host, collected, fused in the mixture, and injected into a separate host. This
gives the host a passive-acquired immunity that lasts for only 2 to 3 months.



DIF: Cognitive Level: Knowledge REF: p. 646 OBJ: 1

TOP: Functions of the Immune System KEY: Nursing Process Step: Implementation



4. A nurse is alerted by the laboratory regarding a patient's complete blood count that shows a large
shift to the left. What should the nurse assess this to mean about cell level count?

a. Neutrophils have dropped by 10%.

b. Basophils have increased by 25%.

c. Neutrophils have increased by 25%.

d. Neutrophils have increased by 60%. - ANS: D

A shift to the left indicates a sharp rise in the neutrophils to approximately 60%. The outpouring of these
cells from the marrow indicates a serious and perhaps overpowering infection. Many of the cells are
young and will not be able to keep up their work of immunity for as long as more mature cells would
maintain immunity.



DIF: Cognitive Level: Comprehension REF: p. 651 OBJ: 3

TOP: Nursing Diagnosis KEY: Nursing Process Step: Nursing Diagnosis



5. Which symptom should a nurse recognize as being pertinent to a possible diagnosis of systemic lupus
erythematosus (SLE)?

a. Butterfly rash of the face

b. Protruding abdomen

c. Thinning hair

d. Bloody diarrhea - ANS: A

The classic butterfly rash of the face is one of the most recognizable signs. Because the symptoms come
and go, SLE is extremely hard to diagnose quickly.

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