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IC
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PATHOPHYSIOLOGY
SI
BA
IC
OG
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
OL
BI
E
8th Edition
TH
Y.
OG
Kathryn L. McCance, Sue E. Huether
OL
SI
HY
OP
TH
PA
, EN
DR
IL
2
CH
D
AN
TS
UL
Contents
AD
Chapter 01: Cellular Biology .......................................................................................................................... 4
IN
ES
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents ................................................... 18
AS
SE
Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases...................................... 31
DI
R
Chapter 04: Genes and Genetic Diseases ................................................................................................... 44
FO
S
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases........................................................... 55
SI
BA
Chapter 06: Epigenetics and Disease .......................................................................................................... 63
IC
OG
Chapter 07: Innate Immunity: Inflammation and Wound Healing ............................................................. 68
OL
BI
Chapter 08: Adaptive Immunity .................................................................................................................. 83
E
TH
Chapter 09: Alterations in Immunity and Inflammation............................................................................. 95
Y.
OG
Chapter 10: Infection ................................................................................................................................ 108
OL
SI
Chapter 11: Stress and Disease ................................................................................................................. 117
HY
OP
Chapter 12: Cancer Biology....................................................................................................................... 124
TH
PA
Chapter 13: Cancer Epidemiology............................................................................................................. 137
Chapter 14: Cancer in Children ................................................................................................................. 143
Chapter 15: Structure and Function of the Neurologic System ................................................................ 148
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function ............................................... 159
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ............... 174
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
.................................................................................................................................................................. 188
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders ........................... 199
Chapter 20: Alterations of Neurologic Function in Children..................................................................... 206
Chapter 21: Mechanisms of Hormonal Regulation................................................................................... 213
Chapter 22: Alterations of Hormonal Regulation ..................................................................................... 222
Chapter 23: Obesity and Disorders of Nutrition ....................................................................................... 234
Chapter 24: Structure and Function of the Reproductive Systems .......................................................... 239
Chapter 25: Alterations of the Female Reproductive System .................................................................. 249
Chapter 26: Alterations of the Male Reproductive System ...................................................................... 259
Chapter 27: Sexually Transmitted Infections ............................................................................................ 265
Chapter 28: Structure and Function of the Hematologic System ............................................................. 273
Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function ......................................... 283
, EN
DR
IL
3
CH
D
AN
Chapter 30: Alterations of Leukocyte and Lymphoid Function ................................................................ 293
TS
UL
Chapter 31: Alterations of Hematologic Function in Children .................................................................. 300
AD
IN
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems ............................... 311
ES
AS
Chapter 33: Alterations of Cardiovascular Function ................................................................................. 324
SE
DI
Chapter 34: Alterations of Cardiovascular Function in Children .............................................................. 338
R
FO
Chapter 35: Structure and Function of the Pulmonary System ................................................................ 346
S
SI
Chapter 36: Alterations of Pulmonary Function ....................................................................................... 356
BA
Chapter 37: Alterations of Pulmonary Function in Children..................................................................... 373
IC
OG
OL
Chapter 38: Structure and Function of the Renal and Urologic Systems ................................................. 381
BI
Chapter 39: Alterations of Renal and Urinary Tract Function .................................................................. 391
E
TH
Y.
Chapter 40: Alterations of Renal and Urinary Tract Function in Children ................................................ 401
OG
OL
Chapter 41: Structure and Function of the Digestive System................................................................... 409
SI
HY
Chapter 42: Alterations of Digestive Function .......................................................................................... 421
OP
TH
Chapter 43: Alterations of Digestive Function in Children ....................................................................... 432
PA
Chapter 44: Structure and Function of the Musculoskeletal System ....................................................... 441
Chapter 45: Alterations of Musculoskeletal Function .............................................................................. 453
Chapter 46: Alterations of Musculoskeletal Function in Children ............................................................ 466
Chapter 47: Structure, Function, and Disorders of the Integument......................................................... 475
Chapter 48: Alterations of the Integument in Children ............................................................................ 486
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults .................................... 494
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children ................................ 502
TH
OP
HY
SI
OL
OG
Y.
TH
E
BI
OL
OG
IC
BA
SI
S
FO
R
DI
SE
AS
ES
IN
AD
UL
TS
AN
D
CH
IL
DR
EN
, EN
DR
IL
CH
D
AN
TS
UL
AD
IN
ES
AS
SE
DI
TEST BANK
R
FO
S
PATHOPHYSIOLOGY
SI
BA
IC
OG
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
OL
BI
E
8th Edition
TH
Y.
OG
Kathryn L. McCance, Sue E. Huether
OL
SI
HY
OP
TH
PA
, EN
DR
IL
2
CH
D
AN
TS
UL
Contents
AD
Chapter 01: Cellular Biology .......................................................................................................................... 4
IN
ES
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents ................................................... 18
AS
SE
Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases...................................... 31
DI
R
Chapter 04: Genes and Genetic Diseases ................................................................................................... 44
FO
S
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases........................................................... 55
SI
BA
Chapter 06: Epigenetics and Disease .......................................................................................................... 63
IC
OG
Chapter 07: Innate Immunity: Inflammation and Wound Healing ............................................................. 68
OL
BI
Chapter 08: Adaptive Immunity .................................................................................................................. 83
E
TH
Chapter 09: Alterations in Immunity and Inflammation............................................................................. 95
Y.
OG
Chapter 10: Infection ................................................................................................................................ 108
OL
SI
Chapter 11: Stress and Disease ................................................................................................................. 117
HY
OP
Chapter 12: Cancer Biology....................................................................................................................... 124
TH
PA
Chapter 13: Cancer Epidemiology............................................................................................................. 137
Chapter 14: Cancer in Children ................................................................................................................. 143
Chapter 15: Structure and Function of the Neurologic System ................................................................ 148
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function ............................................... 159
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ............... 174
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
.................................................................................................................................................................. 188
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders ........................... 199
Chapter 20: Alterations of Neurologic Function in Children..................................................................... 206
Chapter 21: Mechanisms of Hormonal Regulation................................................................................... 213
Chapter 22: Alterations of Hormonal Regulation ..................................................................................... 222
Chapter 23: Obesity and Disorders of Nutrition ....................................................................................... 234
Chapter 24: Structure and Function of the Reproductive Systems .......................................................... 239
Chapter 25: Alterations of the Female Reproductive System .................................................................. 249
Chapter 26: Alterations of the Male Reproductive System ...................................................................... 259
Chapter 27: Sexually Transmitted Infections ............................................................................................ 265
Chapter 28: Structure and Function of the Hematologic System ............................................................. 273
Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function ......................................... 283
, EN
DR
IL
3
CH
D
AN
Chapter 30: Alterations of Leukocyte and Lymphoid Function ................................................................ 293
TS
UL
Chapter 31: Alterations of Hematologic Function in Children .................................................................. 300
AD
IN
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems ............................... 311
ES
AS
Chapter 33: Alterations of Cardiovascular Function ................................................................................. 324
SE
DI
Chapter 34: Alterations of Cardiovascular Function in Children .............................................................. 338
R
FO
Chapter 35: Structure and Function of the Pulmonary System ................................................................ 346
S
SI
Chapter 36: Alterations of Pulmonary Function ....................................................................................... 356
BA
Chapter 37: Alterations of Pulmonary Function in Children..................................................................... 373
IC
OG
OL
Chapter 38: Structure and Function of the Renal and Urologic Systems ................................................. 381
BI
Chapter 39: Alterations of Renal and Urinary Tract Function .................................................................. 391
E
TH
Y.
Chapter 40: Alterations of Renal and Urinary Tract Function in Children ................................................ 401
OG
OL
Chapter 41: Structure and Function of the Digestive System................................................................... 409
SI
HY
Chapter 42: Alterations of Digestive Function .......................................................................................... 421
OP
TH
Chapter 43: Alterations of Digestive Function in Children ....................................................................... 432
PA
Chapter 44: Structure and Function of the Musculoskeletal System ....................................................... 441
Chapter 45: Alterations of Musculoskeletal Function .............................................................................. 453
Chapter 46: Alterations of Musculoskeletal Function in Children ............................................................ 466
Chapter 47: Structure, Function, and Disorders of the Integument......................................................... 475
Chapter 48: Alterations of the Integument in Children ............................................................................ 486
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults .................................... 494
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children ................................ 502
