CHEM 123- Set 11 Notes

set 11

☐
relationship between compounds
I> chiral molecules
1
identical ↳ enantiomers
* •
same physical prope
it it •
rotate light in eq
II directions
diff conformations & not

{
-


clockwise rotat
related
2
Stereoisomers rot
+0 Rts
-



counter -




cc

same MF & connectivity but 3D atom orientation
↳
atom

differs specific rotation :
↳


molecule for an op
A enantiomers ( optical isomers ) (R →
s)
•
mixture of enan
•
2 non -




superimposable stereoisomers
rotation =



ex OH
.
OH

q = spec rot
(% (t ) )( of )-
.
.




(t)

( R) butan -2-01 ( s) butan -2-01
types of solutions
-




D
-




a a
mirrored
÷ chir
optically pure pure
:
into
page ,

÷ a
0"
active mixture
optically
:
OH 2

( not I :|
CI mirrored OH mirrored
about y É about ✗ -




chi
3
optically inactive no
:
axis
axis


A racemic
±
01-1
A
ex ( R) and CS ) -
Carlone has
H .


H
I +50.40 % S carrone


pF•
- =


"
→" lol

µ specific
Br R -
carrone rotat

\
S +720 let ✗
carvone =
-




B diastreomers

but all stereo centres 50.4 =
1×7172 ) +
(I -


✗ 71
• some not
change
ex ,
OH OH 50.4 =
7211 -


72 + 72 ✗
I =
✗
=
0.85 =
85% S

I ⑥ 15% R
OH OH


125,35 ) pentane -2,3 diol 12s ,3R ) pentane -2,3 diol D Fischer projections
- -




- -




COOH
H COOH
µ

o•ÉAaH
1K §g4H HO

'm
"
" " ' µ
" "
d Hf OH
) ¥ ,

,