NR 547 Final Exam – UPDATED Questions with 100% Verified
Answers
Chamberlain University-Illinois
NR 547
NR 547 Final Exam
Study Questions and Answers
Q1 Treatment of depression in postpartum women
A Mild depression Psychotherapy such as cognitive-behavioral therapy (CBT) OR interpersonal therapy Mild
Depression postpartum while breast-feeding Psychotherapy with or without antidepressant (sertraline or paroxetine)
Severe Depression Psychotherapy AND fluoxetine Alternative medications: sertraline or tricyclic antidepressant.
Severe Depression postpartum while breast-feeding Supportive services AND sertraline Alternative medication:
Paroxetine
Q2 Medications for depression with MOA
A Selective Serotonin Reuptake Inhibitors (SSRI's) inhibit 5-HT reuptake Serotonin Norepinephrine Reuptake
Inhibitors (SNRIs) inhibit 5-HT reuptakeinhibit NE reuptake (↑ energy, focus) increase DA in prefrontal cortex (↑
cognition) Norepinephrine Dopamine Reuptake Inhibitors (NDRI) inhibit DA reuptake (↑alertness, motivation) inhibit
NE reuptake (↑energy)
Q3 Prescribing Pearl: Escitalopram (Lexapro)
A no known drug interactions
Q4 Prescribing Pearl: Citalopram (Celexa)
A mild antihistamine effects
Q5 Prescribing Pearl: Fluoxetine (Prozac)
A longest half-life
Q6 Prescribing Pearl: Paroxetine (Paxil)
A also treats social anxiety and insomnia
Q7 Prescribing Pearl: Fluvoxamine (Luvox)
A treats anxious depression smokers require increased dose
Q8 Prescribing Pearl: Sertraline (Zoloft)
NR 547 Final Exam 1
, A also treats social anxiety and hypersomnolence
Q9 Prescribing Pearl: Venlafaxine (Effexor)
A treats both depression and anxiety disorders, ensure trial of higher dose before switching to a different medication
Q10 Prescribing Pearl: Desvenlafaxine (Pristiq)
A effective for perimenopausal vasomotor symptoms
Q11 Prescribing Pearl: Duloxetine (Cymbalta)
A effective for atypical pain at higher doses; appropriate for clients who present with somatic symptoms of depression;
effective for atypical pain, such as fibromyalgia and diabetic neuropathy
Q12 Prescribing Pearl: Bupropion (Wellbutrin)- NDRI
A may improve energy, alertness, and motivation; not first line treatment for anxiety; contraindicated in clients with a
history of seizures
Q13 Choosing an antidepressant:
A 1) selection of primary agent (consider co-morbidities, past treatment response, side effects, etc.) 2) Gradually
increase dose 3) Switch to a different drug within the same class 4) Switch to a drug in a different class 5) Add a
second medication and/or mood stabilizer
Q14 depression
A mood disorder characterized by depressive symptoms lasting longer than 2 weeks. It has been tied to decreased
activity of the prefrontal cortex (attention, mood, memory, personality) and an imbalance of neurotransmitters.
Q15 monoamine hypothesis of depression
A depression occurs as a result of a deficiency of one or all three monoamine transmitters (serotonin, norepinephrine,
and dopamine), while mania may result from an excess
Q16 (USPSTF) recommends depression screening for
A adults 18 years of age or older and adolescents ages 12-18 years old.
Q17 Geriatric Depression Scale
A 1. Components of the GDS: The GDS is a self-report assessment specifically designed for older adults. It often
includes 15 yes/no questions addressing: General mood Feelings of helplessness Energy levels Social withdrawal
Personal satisfaction 2. GDS Scores Interpretation: 0-4 no depression 5-8 mild 9-11 moderate 12-15 severe
NR 547 Final Exam 2
, Q18 American Academy of Pediatrics recommends maternal screening for postpartum depression
A at infants' 1, 2, and 4- month visits.
Q19 A limitation of the Hamilton Depression Rating Scale
A atypical symptoms of depression (e.g., hypersomnia, hyperphagia) are not assessed
Q20 Baseline labs help rule out a medical diagnosis or other condition
A comprehensive metabolic panel, complete blood count, vitamin B12 level, vitamin D level, thyroid function tests, or a
toxicology screen.
Q21 Medical conditions that commonly present with symptoms that mimic depression include
A hypothyroidism, vitamin D deficiency, hypoglycemia, anemia, vitamin B12 deficiency, chronic fatigue syndrome, and
hypotension
Q22 Medications with side effects mimicking depression include
A cannabis, alcohol, clonidine, antidepressants, anticonvulsants, antimigraine agents, corticosteroids, contraceptives,
and varenicline (Chantix). Withdrawal from certain substances, such as cocaine or caffeine, can also lead to
depressive symptoms.
Q23 PHQ-9 screening tool for depression
A 1. Components of the PHQ-9: The PHQ-9 consists of 9 items that reflect the DSM-IV criteria for depression. Each
item is scored from 0 (not at all) to 3 (nearly every day), covering: Interest or pleasure in doing things Feeling down,
depressed, or hopeless Trouble sleeping or sleeping too much Feeling tired or having little energy Poor appetite or
overeating Feeling bad about oneself Trouble concentrating Moving or speaking slowly, or being fidgety/restless
Thoughts of self-harm or suicide 2. PHQ-9 Scores Interpretation: 0–4: Minimal depression 5–9: Mild depression
10–14: Moderate depression 15–19: Moderately severe depression 20–27: Severe depression
Q24 Screening for depression in postpartum women
A at infant months 1,2, & 4 Edinburgh Postnatal Depression Scale (EPDS) Each answer is given a score of 0 to 3 .
The maximum score is 30. score of more than 10 suggests minor or major depression may be present. Further
evaluation is recommended.
Q25 brain imaging in bipolar disorder
A white matter hyperintensities, reduction in gray matter volume, increased ventricular size, and decreased frontal
cortical area volumes
Q26 Manic vs hypomanic
NR 547 Final Exam 3
Answers
Chamberlain University-Illinois
NR 547
NR 547 Final Exam
Study Questions and Answers
Q1 Treatment of depression in postpartum women
A Mild depression Psychotherapy such as cognitive-behavioral therapy (CBT) OR interpersonal therapy Mild
Depression postpartum while breast-feeding Psychotherapy with or without antidepressant (sertraline or paroxetine)
Severe Depression Psychotherapy AND fluoxetine Alternative medications: sertraline or tricyclic antidepressant.
Severe Depression postpartum while breast-feeding Supportive services AND sertraline Alternative medication:
Paroxetine
Q2 Medications for depression with MOA
A Selective Serotonin Reuptake Inhibitors (SSRI's) inhibit 5-HT reuptake Serotonin Norepinephrine Reuptake
Inhibitors (SNRIs) inhibit 5-HT reuptakeinhibit NE reuptake (↑ energy, focus) increase DA in prefrontal cortex (↑
cognition) Norepinephrine Dopamine Reuptake Inhibitors (NDRI) inhibit DA reuptake (↑alertness, motivation) inhibit
NE reuptake (↑energy)
Q3 Prescribing Pearl: Escitalopram (Lexapro)
A no known drug interactions
Q4 Prescribing Pearl: Citalopram (Celexa)
A mild antihistamine effects
Q5 Prescribing Pearl: Fluoxetine (Prozac)
A longest half-life
Q6 Prescribing Pearl: Paroxetine (Paxil)
A also treats social anxiety and insomnia
Q7 Prescribing Pearl: Fluvoxamine (Luvox)
A treats anxious depression smokers require increased dose
Q8 Prescribing Pearl: Sertraline (Zoloft)
NR 547 Final Exam 1
, A also treats social anxiety and hypersomnolence
Q9 Prescribing Pearl: Venlafaxine (Effexor)
A treats both depression and anxiety disorders, ensure trial of higher dose before switching to a different medication
Q10 Prescribing Pearl: Desvenlafaxine (Pristiq)
A effective for perimenopausal vasomotor symptoms
Q11 Prescribing Pearl: Duloxetine (Cymbalta)
A effective for atypical pain at higher doses; appropriate for clients who present with somatic symptoms of depression;
effective for atypical pain, such as fibromyalgia and diabetic neuropathy
Q12 Prescribing Pearl: Bupropion (Wellbutrin)- NDRI
A may improve energy, alertness, and motivation; not first line treatment for anxiety; contraindicated in clients with a
history of seizures
Q13 Choosing an antidepressant:
A 1) selection of primary agent (consider co-morbidities, past treatment response, side effects, etc.) 2) Gradually
increase dose 3) Switch to a different drug within the same class 4) Switch to a drug in a different class 5) Add a
second medication and/or mood stabilizer
Q14 depression
A mood disorder characterized by depressive symptoms lasting longer than 2 weeks. It has been tied to decreased
activity of the prefrontal cortex (attention, mood, memory, personality) and an imbalance of neurotransmitters.
Q15 monoamine hypothesis of depression
A depression occurs as a result of a deficiency of one or all three monoamine transmitters (serotonin, norepinephrine,
and dopamine), while mania may result from an excess
Q16 (USPSTF) recommends depression screening for
A adults 18 years of age or older and adolescents ages 12-18 years old.
Q17 Geriatric Depression Scale
A 1. Components of the GDS: The GDS is a self-report assessment specifically designed for older adults. It often
includes 15 yes/no questions addressing: General mood Feelings of helplessness Energy levels Social withdrawal
Personal satisfaction 2. GDS Scores Interpretation: 0-4 no depression 5-8 mild 9-11 moderate 12-15 severe
NR 547 Final Exam 2
, Q18 American Academy of Pediatrics recommends maternal screening for postpartum depression
A at infants' 1, 2, and 4- month visits.
Q19 A limitation of the Hamilton Depression Rating Scale
A atypical symptoms of depression (e.g., hypersomnia, hyperphagia) are not assessed
Q20 Baseline labs help rule out a medical diagnosis or other condition
A comprehensive metabolic panel, complete blood count, vitamin B12 level, vitamin D level, thyroid function tests, or a
toxicology screen.
Q21 Medical conditions that commonly present with symptoms that mimic depression include
A hypothyroidism, vitamin D deficiency, hypoglycemia, anemia, vitamin B12 deficiency, chronic fatigue syndrome, and
hypotension
Q22 Medications with side effects mimicking depression include
A cannabis, alcohol, clonidine, antidepressants, anticonvulsants, antimigraine agents, corticosteroids, contraceptives,
and varenicline (Chantix). Withdrawal from certain substances, such as cocaine or caffeine, can also lead to
depressive symptoms.
Q23 PHQ-9 screening tool for depression
A 1. Components of the PHQ-9: The PHQ-9 consists of 9 items that reflect the DSM-IV criteria for depression. Each
item is scored from 0 (not at all) to 3 (nearly every day), covering: Interest or pleasure in doing things Feeling down,
depressed, or hopeless Trouble sleeping or sleeping too much Feeling tired or having little energy Poor appetite or
overeating Feeling bad about oneself Trouble concentrating Moving or speaking slowly, or being fidgety/restless
Thoughts of self-harm or suicide 2. PHQ-9 Scores Interpretation: 0–4: Minimal depression 5–9: Mild depression
10–14: Moderate depression 15–19: Moderately severe depression 20–27: Severe depression
Q24 Screening for depression in postpartum women
A at infant months 1,2, & 4 Edinburgh Postnatal Depression Scale (EPDS) Each answer is given a score of 0 to 3 .
The maximum score is 30. score of more than 10 suggests minor or major depression may be present. Further
evaluation is recommended.
Q25 brain imaging in bipolar disorder
A white matter hyperintensities, reduction in gray matter volume, increased ventricular size, and decreased frontal
cortical area volumes
Q26 Manic vs hypomanic
NR 547 Final Exam 3