ATI RN PHARMACOLOGY PROCTORED EXAM 2026/2027 - 400 VERIFIED DRUG
QUESTIONS WITH ANSWERS & RATIONALES | A+
Course: ATI RN Pharmacology CMS 2026/2027 | 400 Verified Questions | 2026/2027 Edition | NGN Format
Original 2026/2027 content based on ATI standards, Lewis, Saunders, NCSBN CJMM. Author-created for study. Not official ATI exam.
1. Warfarin INR 4.8 bleeding antidote
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
2. Heparin therapeutic aPTT
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
3. Gentamicin side effects
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
4. Opioid overdose triad
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
5. Warfarin INR 4.8 bleeding antidote (Variant 5 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
6. Heparin therapeutic aPTT (Variant 6 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
7. Gentamicin side effects (Variant 7 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
,8. Opioid overdose triad (Variant 8 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
9. Warfarin INR 4.8 bleeding antidote (Variant 9 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
10. Heparin therapeutic aPTT (Variant 10 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
11. Gentamicin side effects (Variant 11 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
12. Opioid overdose triad (Variant 12 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
13. Warfarin INR 4.8 bleeding antidote (Variant 13 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
14. Heparin therapeutic aPTT (Variant 14 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
15. Gentamicin side effects (Variant 15 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
,Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
16. Opioid overdose triad (Variant 16 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
17. Warfarin INR 4.8 bleeding antidote (Variant 17 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
18. Heparin therapeutic aPTT (Variant 18 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
19. Gentamicin side effects (Variant 19 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
20. Opioid overdose triad (Variant 20 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
21. Warfarin INR 4.8 bleeding antidote (Variant 21 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
22. Heparin therapeutic aPTT (Variant 22 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
23. Gentamicin side effects (Variant 23 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
, Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
24. Opioid overdose triad (Variant 24 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
25. Warfarin INR 4.8 bleeding antidote (Variant 25 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
26. Heparin therapeutic aPTT (Variant 26 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
27. Gentamicin side effects (Variant 27 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
28. Opioid overdose triad (Variant 28 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
29. Warfarin INR 4.8 bleeding antidote (Variant 29 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
30. Heparin therapeutic aPTT (Variant 30 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
31. Gentamicin side effects (Variant 31 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
QUESTIONS WITH ANSWERS & RATIONALES | A+
Course: ATI RN Pharmacology CMS 2026/2027 | 400 Verified Questions | 2026/2027 Edition | NGN Format
Original 2026/2027 content based on ATI standards, Lewis, Saunders, NCSBN CJMM. Author-created for study. Not official ATI exam.
1. Warfarin INR 4.8 bleeding antidote
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
2. Heparin therapeutic aPTT
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
3. Gentamicin side effects
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
4. Opioid overdose triad
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
5. Warfarin INR 4.8 bleeding antidote (Variant 5 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
6. Heparin therapeutic aPTT (Variant 6 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
7. Gentamicin side effects (Variant 7 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
,8. Opioid overdose triad (Variant 8 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
9. Warfarin INR 4.8 bleeding antidote (Variant 9 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
10. Heparin therapeutic aPTT (Variant 10 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
11. Gentamicin side effects (Variant 11 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
12. Opioid overdose triad (Variant 12 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
13. Warfarin INR 4.8 bleeding antidote (Variant 13 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
14. Heparin therapeutic aPTT (Variant 14 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
15. Gentamicin side effects (Variant 15 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
,Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
16. Opioid overdose triad (Variant 16 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
17. Warfarin INR 4.8 bleeding antidote (Variant 17 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
18. Heparin therapeutic aPTT (Variant 18 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
19. Gentamicin side effects (Variant 19 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
20. Opioid overdose triad (Variant 20 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
21. Warfarin INR 4.8 bleeding antidote (Variant 21 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
22. Heparin therapeutic aPTT (Variant 22 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
23. Gentamicin side effects (Variant 23 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
, Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
24. Opioid overdose triad (Variant 24 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
25. Warfarin INR 4.8 bleeding antidote (Variant 25 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
26. Heparin therapeutic aPTT (Variant 26 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
27. Gentamicin side effects (Variant 27 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
Weight loss
Answer: A
Rationale: Aminoglycosides: nephrotoxic (creatinine), ototoxic (hearing, tinnitus), monitor peak/trough.
28. Opioid overdose triad (Variant 28 - 2026/2027)
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
HTN
Answer: A
Rationale: Opioid overdose: resp depression, pinpoint pupils, CNS depression. Naloxone antidote.
29. Warfarin INR 4.8 bleeding antidote (Variant 29 - 2026/2027)
Vitamin K + 4F-PCC
Protamine
Naloxone
Flumazenil
Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed.
30. Heparin therapeutic aPTT (Variant 30 - 2026/2027)
60-80 seconds
10-20
100-150
0-10
Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec. Monitor platelets for HIT.
31. Gentamicin side effects (Variant 31 - 2026/2027)
Nephrotoxicity and ototoxicity
Hyperkalemia
No effects
