HESI RN PHARMACOLOGY EXAM 2026/2027 V1 V2 - 350 PHARM QUESTIONS WITH
ANSWERS & RATIONALES | A+
Course: HESI RN Pharmacology 2026/2027 | 350 Questions
About: Most tested HESI Pharm: cardiac, antibiotics, psych, endocrine, antidotes, dosage calculations, side effects, nursing considerations.
Original content created for 2026/2027 academic year based on HESI, ATI, NCSBN NGN standards, Lewis, Saunders. Not copied from official exams.
[1] Aminoglycoside gentamicin: Monitor for?
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[2] Opioid overdose: Triad and antidote?
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[3] Warfarin teaching: Avoid?
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[4] Aminoglycoside gentamicin: Monitor for? - Variant Case 4 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[5] Opioid overdose: Triad and antidote? - Variant Case 5 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[6] Warfarin teaching: Avoid? - Variant Case 6 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[7] Aminoglycoside gentamicin: Monitor for? - Variant Case 7 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
,Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[8] Opioid overdose: Triad and antidote? - Variant Case 8 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[9] Warfarin teaching: Avoid? - Variant Case 9 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[10] Aminoglycoside gentamicin: Monitor for? - Variant Case 10 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[11] Opioid overdose: Triad and antidote? - Variant Case 11 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[12] Warfarin teaching: Avoid? - Variant Case 12 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[13] Aminoglycoside gentamicin: Monitor for? - Variant Case 13 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[14] Opioid overdose: Triad and antidote? - Variant Case 14 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[15] Warfarin teaching: Avoid? - Variant Case 15 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
,Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[16] Aminoglycoside gentamicin: Monitor for? - Variant Case 16 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[17] Opioid overdose: Triad and antidote? - Variant Case 17 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[18] Warfarin teaching: Avoid? - Variant Case 18 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[19] Aminoglycoside gentamicin: Monitor for? - Variant Case 19 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[20] Opioid overdose: Triad and antidote? - Variant Case 20 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[21] Warfarin teaching: Avoid? - Variant Case 21 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[22] Aminoglycoside gentamicin: Monitor for? - Variant Case 22 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[23] Opioid overdose: Triad and antidote? - Variant Case 23 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
, Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[24] Warfarin teaching: Avoid? - Variant Case 24 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[25] Aminoglycoside gentamicin: Monitor for? - Variant Case 25 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[26] Opioid overdose: Triad and antidote? - Variant Case 26 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[27] Warfarin teaching: Avoid? - Variant Case 27 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[28] Aminoglycoside gentamicin: Monitor for? - Variant Case 28 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[29] Opioid overdose: Triad and antidote? - Variant Case 29 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[30] Warfarin teaching: Avoid? - Variant Case 30 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[31] Aminoglycoside gentamicin: Monitor for? - Variant Case 31 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
ANSWERS & RATIONALES | A+
Course: HESI RN Pharmacology 2026/2027 | 350 Questions
About: Most tested HESI Pharm: cardiac, antibiotics, psych, endocrine, antidotes, dosage calculations, side effects, nursing considerations.
Original content created for 2026/2027 academic year based on HESI, ATI, NCSBN NGN standards, Lewis, Saunders. Not copied from official exams.
[1] Aminoglycoside gentamicin: Monitor for?
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[2] Opioid overdose: Triad and antidote?
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[3] Warfarin teaching: Avoid?
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[4] Aminoglycoside gentamicin: Monitor for? - Variant Case 4 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[5] Opioid overdose: Triad and antidote? - Variant Case 5 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[6] Warfarin teaching: Avoid? - Variant Case 6 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[7] Aminoglycoside gentamicin: Monitor for? - Variant Case 7 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
,Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[8] Opioid overdose: Triad and antidote? - Variant Case 8 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[9] Warfarin teaching: Avoid? - Variant Case 9 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[10] Aminoglycoside gentamicin: Monitor for? - Variant Case 10 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[11] Opioid overdose: Triad and antidote? - Variant Case 11 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[12] Warfarin teaching: Avoid? - Variant Case 12 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[13] Aminoglycoside gentamicin: Monitor for? - Variant Case 13 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[14] Opioid overdose: Triad and antidote? - Variant Case 14 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[15] Warfarin teaching: Avoid? - Variant Case 15 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
,Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[16] Aminoglycoside gentamicin: Monitor for? - Variant Case 16 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[17] Opioid overdose: Triad and antidote? - Variant Case 17 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[18] Warfarin teaching: Avoid? - Variant Case 18 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[19] Aminoglycoside gentamicin: Monitor for? - Variant Case 19 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[20] Opioid overdose: Triad and antidote? - Variant Case 20 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[21] Warfarin teaching: Avoid? - Variant Case 21 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[22] Aminoglycoside gentamicin: Monitor for? - Variant Case 22 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[23] Opioid overdose: Triad and antidote? - Variant Case 23 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
, Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[24] Warfarin teaching: Avoid? - Variant Case 24 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[25] Aminoglycoside gentamicin: Monitor for? - Variant Case 25 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[26] Opioid overdose: Triad and antidote? - Variant Case 26 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[27] Warfarin teaching: Avoid? - Variant Case 27 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[28] Aminoglycoside gentamicin: Monitor for? - Variant Case 28 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
No monitoring
Weight only
Answer: A
Rationale: Aminoglycosides nephrotoxic and ototoxic. Monitor peak/trough, creatinine, I&O;, hearing changes, 8th cranial nerve.
[29] Opioid overdose: Triad and antidote? - Variant Case 29 2026/2027
Respiratory depression, pinpoint pupils, decreased LOC - Naloxone
Tachycardia
Dilated pupils
Hypertension
Answer: A
Rationale: Opioid overdose triad: resp depression, pinpoint pupils, CNS depression. Give naloxone 0.4-2 mg IV, monitor for re-sedation.
[30] Warfarin teaching: Avoid? - Variant Case 30 2026/2027
Inconsistent Vitamin K intake, alcohol, NSAIDs, cranberry
Consistent diet
Regular INR checks are not needed
No teaching
Answer: A
Rationale: Warfarin: keep Vitamin K consistent, avoid alcohol, NSAIDs increase bleed risk, check INR regularly, wear MedicAlert.
[31] Aminoglycoside gentamicin: Monitor for? - Variant Case 31 2026/2027
Nephrotoxicity: creatinine, BUN, and ototoxicity: hearing loss, tinnitus
Hyperkalemia only
