ATI RN PHARMACOLOGY PROCTORED EXAM 2025/2026 - 330 DRUG
QUESTIONS WITH ANSWERS & RATIONALES | A+
Course: ATI RN Pharmacology CMS Proctored 2025/2026 | Total: 200 Verified Questions
Description: Pharmacology proctored: drug classes, side effects, antidotes, dosage calc, nursing considerations - most tested
topics.
Original study material based on ATI testing standards, Lewis Med-Surg, Saunders NCLEX, and NCSBN Clinical Judgment Measurement Model. All
questions author-created, not copied from ATI.
[1] Warfarin client INR 4.8 bleeding. Antidote?
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[2] Heparin infusion: therapeutic aPTT?
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[3] Metformin holds before?
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[4] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 4)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[5] Heparin infusion: therapeutic aPTT? (Case Variant 5)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[6] Metformin holds before? (Case Variant 6)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
,Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[7] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 7)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[8] Heparin infusion: therapeutic aPTT? (Case Variant 8)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[9] Metformin holds before? (Case Variant 9)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[10] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 10)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[11] Heparin infusion: therapeutic aPTT? (Case Variant 11)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[12] Metformin holds before? (Case Variant 12)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[13] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 13)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
, Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[14] Heparin infusion: therapeutic aPTT? (Case Variant 14)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[15] Metformin holds before? (Case Variant 15)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[16] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 16)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[17] Heparin infusion: therapeutic aPTT? (Case Variant 17)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[18] Metformin holds before? (Case Variant 18)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[19] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 19)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[20] Heparin infusion: therapeutic aPTT? (Case Variant 20)
60-80 seconds
10-20
QUESTIONS WITH ANSWERS & RATIONALES | A+
Course: ATI RN Pharmacology CMS Proctored 2025/2026 | Total: 200 Verified Questions
Description: Pharmacology proctored: drug classes, side effects, antidotes, dosage calc, nursing considerations - most tested
topics.
Original study material based on ATI testing standards, Lewis Med-Surg, Saunders NCLEX, and NCSBN Clinical Judgment Measurement Model. All
questions author-created, not copied from ATI.
[1] Warfarin client INR 4.8 bleeding. Antidote?
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[2] Heparin infusion: therapeutic aPTT?
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[3] Metformin holds before?
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[4] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 4)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[5] Heparin infusion: therapeutic aPTT? (Case Variant 5)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[6] Metformin holds before? (Case Variant 6)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
,Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[7] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 7)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[8] Heparin infusion: therapeutic aPTT? (Case Variant 8)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[9] Metformin holds before? (Case Variant 9)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[10] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 10)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[11] Heparin infusion: therapeutic aPTT? (Case Variant 11)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[12] Metformin holds before? (Case Variant 12)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[13] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 13)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
, Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[14] Heparin infusion: therapeutic aPTT? (Case Variant 14)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[15] Metformin holds before? (Case Variant 15)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[16] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 16)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[17] Heparin infusion: therapeutic aPTT? (Case Variant 17)
60-80 seconds
10-20
100-150
0-10
Correct Answer: A
Rationale: Heparin therapeutic aPTT 60-80 sec (1.5-2x control). Monitor platelets for HIT.
[18] Metformin holds before? (Case Variant 18)
Iodinated contrast, surgery, AKI risk
Headache
Mild cold
Exercise
Correct Answer: A
Rationale: Hold metformin before contrast to prevent lactic acidosis if contrast-induced AKI. Also hold in sepsis, hypotension.
[19] Warfarin client INR 4.8 bleeding. Antidote? (Case Variant 19)
Vitamin K and 4F-PCC
Protamine sulfate
Naloxone
Flumazenil
Correct Answer: A
Rationale: Warfarin overdose: Vitamin K PO/IV, PCC for life-threatening bleed. Monitor INR.
[20] Heparin infusion: therapeutic aPTT? (Case Variant 20)
60-80 seconds
10-20
