ANCC FNP Exam Version 2 Family Nurse Practitioner
2026/2027 – Questions and Answers | 100% Verified |
Detailed Rationales – Pass Guaranteed – A+ Graded
300 QUESTIONS
TABLE OF CONTENTS
# TOPIC
1 Cardiovascular
2 Respiratory
3 Endocrine
4 Gastrointestinal
5 Renal/GU
6 Women’s Health
7 Men’s Health
8 Pediatrics
9 Mental Health
10 Musculoskeletal
11 Dermatology
12 Neurology
13 Infectious Disease
14 Geriatrics
15 Professional Issues
,Q1
A 56-year-old male with hypertension and diabetes has BP 148/92. First-line med?
A) HCTZ
B) Lisinopril CORRECT
C) Amlodipine
D) Metoprolol
Rationale
ACE inhibitor preferred in diabetes with hypertension for renal protection.
Q2
A 45-year-old female with migraine with aura requests OCP. Contraindicated?
A) Progestin-only pill
B) Combined OCP CORRECT
C) Copper IUD
D) Levonorgestrel IUD
Rationale
Estrogen increases stroke risk in migraine with aura.
Q3
A 62-year-old male with COPD FEV1 45% has acute exacerbation. Antibiotic?
A) Doxycycline
B) Levofloxacin CORRECT
C) Azithromycin
D) Amoxicillin
Rationale
Severe COPD or frequent exacerbations require fluoroquinolone or amox-clav.
2
,Q4
A 30-year-old female has dysuria, frequency, nitrites. Treatment?
A) Nitrofurantoin x5 days CORRECT
B) Nitrofurantoin x5 days
C) Cipro x3 days
D) Amoxicillin
Rationale
First-line for uncomplicated cystitis.
Q5
A 68-year-old female has T-score −2.8. First-line?
A) Alendronate CORRECT
B) Alendronate
C) Teriparatide
D) Raloxifene
Rationale
Bisphosphonates first-line for osteoporosis.
Q6
A 52-year-old male has LDL 190. Therapy?
A) Lifestyle only
B) High-intensity statin CORRECT
C) Moderate statin
D) Ezetimibe
Rationale
LDL ≥190 warrants high-intensity statin.
3
, Q7
A 28-year-old female has monospot positive. Avoid?
A) Amoxicillin CORRECT
B) Amoxicillin
C) Ibuprofen
D) Acetaminophen
Rationale
Causes rash in EBV mononucleosis.
Q8
A 72-year-old male has painless hematuria. Initial test?
A) CT urogram CORRECT
B) CT urogram
C) Cystoscopy
D) Ultrasound
Rationale
Best initial imaging for painless hematuria.
Q9
A 60-year-old female has TSH 25, free T4 low. Starting dose?
A) 25 mcg
B) 1.6 mcg/kg CORRECT
C) 100 mcg
D) 50 mcg
Rationale
Full replacement dose in healthy adults.
4
2026/2027 – Questions and Answers | 100% Verified |
Detailed Rationales – Pass Guaranteed – A+ Graded
300 QUESTIONS
TABLE OF CONTENTS
# TOPIC
1 Cardiovascular
2 Respiratory
3 Endocrine
4 Gastrointestinal
5 Renal/GU
6 Women’s Health
7 Men’s Health
8 Pediatrics
9 Mental Health
10 Musculoskeletal
11 Dermatology
12 Neurology
13 Infectious Disease
14 Geriatrics
15 Professional Issues
,Q1
A 56-year-old male with hypertension and diabetes has BP 148/92. First-line med?
A) HCTZ
B) Lisinopril CORRECT
C) Amlodipine
D) Metoprolol
Rationale
ACE inhibitor preferred in diabetes with hypertension for renal protection.
Q2
A 45-year-old female with migraine with aura requests OCP. Contraindicated?
A) Progestin-only pill
B) Combined OCP CORRECT
C) Copper IUD
D) Levonorgestrel IUD
Rationale
Estrogen increases stroke risk in migraine with aura.
Q3
A 62-year-old male with COPD FEV1 45% has acute exacerbation. Antibiotic?
A) Doxycycline
B) Levofloxacin CORRECT
C) Azithromycin
D) Amoxicillin
Rationale
Severe COPD or frequent exacerbations require fluoroquinolone or amox-clav.
2
,Q4
A 30-year-old female has dysuria, frequency, nitrites. Treatment?
A) Nitrofurantoin x5 days CORRECT
B) Nitrofurantoin x5 days
C) Cipro x3 days
D) Amoxicillin
Rationale
First-line for uncomplicated cystitis.
Q5
A 68-year-old female has T-score −2.8. First-line?
A) Alendronate CORRECT
B) Alendronate
C) Teriparatide
D) Raloxifene
Rationale
Bisphosphonates first-line for osteoporosis.
Q6
A 52-year-old male has LDL 190. Therapy?
A) Lifestyle only
B) High-intensity statin CORRECT
C) Moderate statin
D) Ezetimibe
Rationale
LDL ≥190 warrants high-intensity statin.
3
, Q7
A 28-year-old female has monospot positive. Avoid?
A) Amoxicillin CORRECT
B) Amoxicillin
C) Ibuprofen
D) Acetaminophen
Rationale
Causes rash in EBV mononucleosis.
Q8
A 72-year-old male has painless hematuria. Initial test?
A) CT urogram CORRECT
B) CT urogram
C) Cystoscopy
D) Ultrasound
Rationale
Best initial imaging for painless hematuria.
Q9
A 60-year-old female has TSH 25, free T4 low. Starting dose?
A) 25 mcg
B) 1.6 mcg/kg CORRECT
C) 100 mcg
D) 50 mcg
Rationale
Full replacement dose in healthy adults.
4
