1|Page
HESI A2 2026 QUESTIONS AND DETAILED ANSWERS LATEST
VERSION GRADED A+
HESI A2 Practice test questions
Which of the following is NOT a function of the digestive tract?
a) to use enzymes to break down food
b) to perform gas exchange
c) to remove waste from the body
d) to use peristalsis to move food along
b) to perform gas exchange
Gas exchange is a function of the respiratory system
The body, at all times, attempts to maintain homeostasis. The best definition of
homeostasis is:
a) a process that maintains the stability of the human body's internal
environment in response to changes in internal and external conditions
b) a function via which the body breaks down glucose to use as energy
c)a process that maintains the immune system's defenses
d) a process in which the body resists change to genetic structure
a) a process that maintains the stability of the human body's internal environment in
response to changes in internal and external conditions
,2|Page
The endocrine system of the body is responsible for:
a) defense through the use of antibodies
b) communication through the use of hormones
c) metabolism through the use of enzymes
d) blood flow through the use of the heart muscle
b) communication through the use of hormones
Anatomical position shows the body in a(n) ________ position.
a) lateral
b) superior
c) anterior
d) posterior
c) anterior
Vitamin K is created in the:
a) liver
b) lungs
c) intestinal tract
d) pancreas
c) intestinal tract
The largest organ in the body is the ________.
a) skin
b) GI tract
c) femur
d) stomach
a) skin
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A medical scientists wants to study the parenchyma of the kidney. This
scientist would correctly be known, most specifically, as a:
a) biologist
b) doctor
c) anatomist
d) histologist
d) histologist
Histology is the study of tissues.
What is Erythropoiesis?
a) red blood cell formation
b) white blood cell formation
c) the destruction of red blood cells
d) the destruction of white blood cells
a) red blood cell formation
Blood cell formation is called Hemopoiesis.
Erythro- red blood cells
In which part of the body is keratin NOT found?
a) hair
b) skin
c) nails
d) teeth
d) teeth
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Keratin is a family of fibrous structural proteins. Keratin is the key structural
component of hair, nails, and the outer layer of human skin
What is the relationship between sarcomeres and muscle cells?
a) sarcomeres are muscle cells
b) sarcomeres contain muscle cells
c) muscle cells contain myofibrils, which in turn are made up of sarcomeres
d) muscle cells contain sarcomeres, which in turn are made up of myofibrils
c) muscle cells contain myofibrils, which in turn are made up of sarcomeres
A person who has torn their vastus lateralis muscle will need which of the
following?
a) an arm sling
b) a cane or crutches
c) insulin
d) a neck brace
b) a cane or crutches
The vastus lateralis muscle is a voluntary muscle in the legs. It is part of the
quadriceps.
Muscles produce contraction due to the sliding of:
a) filaments
b) sarcomeres
c) flexors
d) neutrons
HESI A2 2026 QUESTIONS AND DETAILED ANSWERS LATEST
VERSION GRADED A+
HESI A2 Practice test questions
Which of the following is NOT a function of the digestive tract?
a) to use enzymes to break down food
b) to perform gas exchange
c) to remove waste from the body
d) to use peristalsis to move food along
b) to perform gas exchange
Gas exchange is a function of the respiratory system
The body, at all times, attempts to maintain homeostasis. The best definition of
homeostasis is:
a) a process that maintains the stability of the human body's internal
environment in response to changes in internal and external conditions
b) a function via which the body breaks down glucose to use as energy
c)a process that maintains the immune system's defenses
d) a process in which the body resists change to genetic structure
a) a process that maintains the stability of the human body's internal environment in
response to changes in internal and external conditions
,2|Page
The endocrine system of the body is responsible for:
a) defense through the use of antibodies
b) communication through the use of hormones
c) metabolism through the use of enzymes
d) blood flow through the use of the heart muscle
b) communication through the use of hormones
Anatomical position shows the body in a(n) ________ position.
a) lateral
b) superior
c) anterior
d) posterior
c) anterior
Vitamin K is created in the:
a) liver
b) lungs
c) intestinal tract
d) pancreas
c) intestinal tract
The largest organ in the body is the ________.
a) skin
b) GI tract
c) femur
d) stomach
a) skin
,3|Page
A medical scientists wants to study the parenchyma of the kidney. This
scientist would correctly be known, most specifically, as a:
a) biologist
b) doctor
c) anatomist
d) histologist
d) histologist
Histology is the study of tissues.
What is Erythropoiesis?
a) red blood cell formation
b) white blood cell formation
c) the destruction of red blood cells
d) the destruction of white blood cells
a) red blood cell formation
Blood cell formation is called Hemopoiesis.
Erythro- red blood cells
In which part of the body is keratin NOT found?
a) hair
b) skin
c) nails
d) teeth
d) teeth
, 4|Page
Keratin is a family of fibrous structural proteins. Keratin is the key structural
component of hair, nails, and the outer layer of human skin
What is the relationship between sarcomeres and muscle cells?
a) sarcomeres are muscle cells
b) sarcomeres contain muscle cells
c) muscle cells contain myofibrils, which in turn are made up of sarcomeres
d) muscle cells contain sarcomeres, which in turn are made up of myofibrils
c) muscle cells contain myofibrils, which in turn are made up of sarcomeres
A person who has torn their vastus lateralis muscle will need which of the
following?
a) an arm sling
b) a cane or crutches
c) insulin
d) a neck brace
b) a cane or crutches
The vastus lateralis muscle is a voluntary muscle in the legs. It is part of the
quadriceps.
Muscles produce contraction due to the sliding of:
a) filaments
b) sarcomeres
c) flexors
d) neutrons
