NR 565 MIDTERM EXAM LEARNING
WORKBOOK 2026 SYSTEMS BASED PHYSICAL
ASSESSMENT AND CLINICAL FINDINGS
◉ Can be used in pregnancy/breastfeeding, as monotherapy or
adjunct therapy with a statin or fibrate. Answer: Ezetimibe Use
◉ Cholesterol Absorption Inhibitor that lowers cholesterol levels by
decreasing absorption from the small intestine, without affecting
triglycerides. Answer: Ezetimibe
◉ Non-drug measures to lower LDL, including diet, exercise, weight
control, and smoking cessation. Answer: Lifestyle Changes for High
Cholesterol
◉ Non-statins like fibrates, ezetimibe, bile acid sequestrants, or
statins for generally well-tolerated side effects. Answer: Minimizing
Side Effects
◉ Direct relaxant effect on vascular smooth muscles, dilation of
coronary vessels, reduction of preload and afterload, and promotion
of vasodilation. Answer: Organic Nitrates Therapeutic Action
, ◉ Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de
pointes, including grapefruit juice, HIV protease inhibitors,
macrolide antibiotics, azole antifungal drugs, and some CCB.
Answer: Ranolazine Contraindications
◉ Avoid in children under 10. Answer: Statin Prescription Age
◉ Promotes relaxation of coronary artery spasm, increasing cardiac
oxygen supply. Answer: CCB Role in Variant Angina
◉ Aldosterone antagonist that promotes myocardial remodeling and
fibrosis to help with symptoms. Answer: HF Worsening Symptoms
Medication
◉ Promotes relaxation of peripheral arterioles, decreasing afterload
and reducing cardiac oxygen demand. Answer: CCB Stable Angina
◉ Prescribe a BB to help with increased heart rate. Answer: Nitro
Patches Side Effect Response
◉ When not used correctly, they lead to increased side effects,
adverse reactions, and toxicity. Answer: CYP450 Inhibitors and
Reducers
WORKBOOK 2026 SYSTEMS BASED PHYSICAL
ASSESSMENT AND CLINICAL FINDINGS
◉ Can be used in pregnancy/breastfeeding, as monotherapy or
adjunct therapy with a statin or fibrate. Answer: Ezetimibe Use
◉ Cholesterol Absorption Inhibitor that lowers cholesterol levels by
decreasing absorption from the small intestine, without affecting
triglycerides. Answer: Ezetimibe
◉ Non-drug measures to lower LDL, including diet, exercise, weight
control, and smoking cessation. Answer: Lifestyle Changes for High
Cholesterol
◉ Non-statins like fibrates, ezetimibe, bile acid sequestrants, or
statins for generally well-tolerated side effects. Answer: Minimizing
Side Effects
◉ Direct relaxant effect on vascular smooth muscles, dilation of
coronary vessels, reduction of preload and afterload, and promotion
of vasodilation. Answer: Organic Nitrates Therapeutic Action
, ◉ Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de
pointes, including grapefruit juice, HIV protease inhibitors,
macrolide antibiotics, azole antifungal drugs, and some CCB.
Answer: Ranolazine Contraindications
◉ Avoid in children under 10. Answer: Statin Prescription Age
◉ Promotes relaxation of coronary artery spasm, increasing cardiac
oxygen supply. Answer: CCB Role in Variant Angina
◉ Aldosterone antagonist that promotes myocardial remodeling and
fibrosis to help with symptoms. Answer: HF Worsening Symptoms
Medication
◉ Promotes relaxation of peripheral arterioles, decreasing afterload
and reducing cardiac oxygen demand. Answer: CCB Stable Angina
◉ Prescribe a BB to help with increased heart rate. Answer: Nitro
Patches Side Effect Response
◉ When not used correctly, they lead to increased side effects,
adverse reactions, and toxicity. Answer: CYP450 Inhibitors and
Reducers
