Pharmacology for Professional
Nursing | Rasmussen | Latest 2026
/ 2027
Question:
Direct and indirect acting cholinomimetic and cholinolytic transmitters
Answer:
Direct works on the post synaptic receptors (stimulating or blocking) and
indirect acts on the transmitter in the terminal or presynaptically (like
presynaptic inhibition of Ach release by snake venom)
Question:
What does cholinergic stimulation result in?
Answer:
SLUD (Salivation, Lacrimation, Urination, and Defecation)
,Question:
Cimeveline (evoxac)
Answer:
sialagogue, DDI with drugs that inhibit 2D6 and 3A4 due to the metabolism
of this drug is through these two enzymes, contraindicated in those
deficient in 2D6 also
Question:
Exaggerated muscarinic effects
Answer:
Extreme salivation/lacrimation
Involuntary defecation/urination
Difficulty breathing due to bronchial constriction and secretion
Question:
Aricept
Answer:
a cholinesterase inhibitor drug used to prolong the half life of
acetylecholine giving the transmitter a better ability to stimulate
,Question:
Exaggerated nicotinic effects
Answer:
overstimulation leading to paralysis of respiratory muscles, delayed
neurotoxicity
Question:
Malathion
Answer:
organophosphate (pesticide) that is an irreversible cholinesterase inhibitor
Question:
Two examples of irreversible cholinesterase inhibitors
Answer:
*sarin*-nerve gas that is an irreversible cholinesterase inhibitor
*malathion*-organophosphate (pesticide) that is an irreversible
cholinesterase inhibitor
, Question:
Anticholinergic drugs
Answer:
antimuscarinic, neuromuscular jxn blockers, and ganglionic blocking drugs
Question:
Antimuscarinic drugs
Answer:
atropine and scopolamine, act as competitive receptor blockers a
postganglionic postsynaptic muscarinic receptor sites
Question:
Which muscarinic receptors are most important to us (dentists)?
Answer:
M3 receptors are most important to us (involved in salivary flow)
Question:
Neuromuscular jxn blockers
Answer:
curare, succinycholine, these act at nicotinic receptors at the
neuromuscular jxn of skeletal muscle causing paralysis