for Professional Nursing | Exam 1 |
Latest - Rasmussen
Question:
What is the primary pathophysiology of Parkinson disease?
Answer:
Low dopamine and excessive acetylcholine activity
Question:
What is the most effective treatment for motor symptoms of Parkinson
disease?
Answer:
Levodopa
,Question:
Why is levodopa effective in treating Parkinson disease?
Answer:
It crosses the blood-brain barrier and is converted to dopamine
Question:
Why is carbidopa administered with levodopa?
Answer:
To prevent decarboxylation of levodopa in the intestine and peripheral
tissues
Question:
How do high-protein meals affect carbidopa-levodopa therapy?
Answer:
They reduce the therapeutic effect by interfering with absorption
, Question:
What are the expected adverse effects of dopamine agonists like
pramipexole?
Answer:
Nausea
Dyskinesia
Postural hypotension
Hallucinations
Question:
What is the term for the abrupt, unpredictable loss of response to
levodopa?
Answer:
On-off phenomenon
Question:
Which drug is combined with levodopa to inhibit COMT and prolong its
action?
Answer:
Entacapone