HESI A2
Anatomy & Physiology 2026 | Practice Questions,
Answers & Detailed Rationales
Resource Features
➢ HESI A2 A&P practice questions
➢ Answers for self-assessment
➢ Detailed rationales
➢ Body-system review
➢ Anatomy and physiology concept reinforcement
➢ 2026-focused review material
, HESI A2 Anatomy & Physiology 2026 |
Practice Questions, Answers & Detailed
Rationales
Question 1
What is erythropoiesis and where does it occur?
A. The formation of red blood cells; Heart
B. The formation of white blood cells; Spleen
C. The formation of bile; Liver
D. The formation of red blood cells; Red bone marrow
Answer: D. The formation of red blood cells; Red bone marrow
Explanation: Erythropoiesis is the production of red blood cells. In the
early development of a fetus, erythropoiesis takes place in the yolk sac,
spleen, and liver. However, after birth, all erythropoiesis occurs in the bone
marrow.
Question 2
Which of the following male reproductive organs is also a part of the
urinary system?
,A. Epididymis
B. Vas deferens
C. Urethra
D. Ureter
Answer: C. Urethra
Explanation: In males, the urethra is the tube through which urine is
voided. It is also the tube that semen flows through during sexual activity.
Therefore, it is part of both the urinary and reproductive systems in males.
Question 3
The shoulder is an example of which type of synovial joint?
A. Ball-and-socket
B. Pivot
C. Saddle
D. Hinge
Answer: A. Ball-and-socket
Question 4
What is the function of endocrine glands?
A. They secrete products directly into a duct that carries the products to
where they are needed.
, B. They transmit nerve impulses between parts of the body.
C. They secrete hormones directly into the blood.
Answer: C. They secrete hormones directly into the blood.
Question 5
A sprain occurs when which of the following structures is stretched or
torn?
A. Ligament
B. Tendon
C. Muscle
D. Fibrous joint
Answer: A. Ligament
Question 6
Which of the following organelles would you expect to find an
abundance of in leukocytes?
A. Ribosomes
B. Lysosomes
C. Mitochondria
D. Golgi bodies
Answer: B. Lysosomes
Anatomy & Physiology 2026 | Practice Questions,
Answers & Detailed Rationales
Resource Features
➢ HESI A2 A&P practice questions
➢ Answers for self-assessment
➢ Detailed rationales
➢ Body-system review
➢ Anatomy and physiology concept reinforcement
➢ 2026-focused review material
, HESI A2 Anatomy & Physiology 2026 |
Practice Questions, Answers & Detailed
Rationales
Question 1
What is erythropoiesis and where does it occur?
A. The formation of red blood cells; Heart
B. The formation of white blood cells; Spleen
C. The formation of bile; Liver
D. The formation of red blood cells; Red bone marrow
Answer: D. The formation of red blood cells; Red bone marrow
Explanation: Erythropoiesis is the production of red blood cells. In the
early development of a fetus, erythropoiesis takes place in the yolk sac,
spleen, and liver. However, after birth, all erythropoiesis occurs in the bone
marrow.
Question 2
Which of the following male reproductive organs is also a part of the
urinary system?
,A. Epididymis
B. Vas deferens
C. Urethra
D. Ureter
Answer: C. Urethra
Explanation: In males, the urethra is the tube through which urine is
voided. It is also the tube that semen flows through during sexual activity.
Therefore, it is part of both the urinary and reproductive systems in males.
Question 3
The shoulder is an example of which type of synovial joint?
A. Ball-and-socket
B. Pivot
C. Saddle
D. Hinge
Answer: A. Ball-and-socket
Question 4
What is the function of endocrine glands?
A. They secrete products directly into a duct that carries the products to
where they are needed.
, B. They transmit nerve impulses between parts of the body.
C. They secrete hormones directly into the blood.
Answer: C. They secrete hormones directly into the blood.
Question 5
A sprain occurs when which of the following structures is stretched or
torn?
A. Ligament
B. Tendon
C. Muscle
D. Fibrous joint
Answer: A. Ligament
Question 6
Which of the following organelles would you expect to find an
abundance of in leukocytes?
A. Ribosomes
B. Lysosomes
C. Mitochondria
D. Golgi bodies
Answer: B. Lysosomes
