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HESI A2 Anatomy & Physiology Version 1 & 2 | Practice Questions, Answers & Detailed Rationales | 2026/2027

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Prepare for the HESI A2 Anatomy & Physiology section with a comprehensive study and practice resource covering major body systems, anatomical structures, physiological processes, and essential A&P concepts. This resource is designed to help students review important concepts, practice exam-style questions, understand answers through detailed rationales, and identify areas requiring additional study.

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HESI A2
Anatomy & Physiology Version 1 & 2 | Practice Questions,
Answers & Detailed Rationales | 2026/2027

Resource Features
• Version 1 & Version 2 practice preparation
• Practice questions and answers
• Detailed rationales
• Anatomy & physiology review
• Comprehensive HESI A2 preparation
• 2026/2027-focused study material

, HESI A2 Anatomy & Physiology Version 1 & 2 |
Practice Questions, Answers & Detailed Rationales
| 2026/2027

1. What is a characteristic of viral herpes?

• A. Skin eruption
• B. Fever
• C. Swelling
• D. Pain

Answer: A. Skin eruption

Rationale: Viral herpes is characterized by skin eruptions,
typically presenting as vesicles or blisters on the skin or mucous
membranes.

2. When a boxer gets hit and has a deviated septum, which
bone is affected?

• A. Nasal bone
• B. Vomer
• C. Maxilla
• D. Ethmoid bone

,Answer: B. Vomer

Rationale: The vomer is the bone that forms the inferior portion
of the nasal septum. Trauma to the nose can cause the vomer to
deviate, resulting in a deviated septum.

3. Which of the following is a structure found in the upper
respiratory tract?

• A. Trachea
• B. Pharynx
• C. Bronchi
• D. Alveoli

Answer: B. Pharynx

Rationale: The upper respiratory tract includes the nose, nasal
cavity, pharynx, and larynx. The pharynx is a common passageway
for both air and food.

4. A person who has damage to their ulnar nerve will have
decreased sensation in which area?

• A. Hand and fingers
• B. Arm, inability to abduct arms and fingers
• C. Shoulder

, • D. Neck

Answer: B. Arm, inability to abduct arms and fingers

Rationale: The ulnar nerve innervates muscles of the forearm and
hand. Damage to the ulnar nerve results in decreased sensation
and weakness in the arm, particularly affecting the ability to
abduct the fingers.

5. Which bone does not articulate with any other bone?

• A. Mandible
• B. Hyoid bone
• C. Temporal bone
• D. Occipital bone

Answer: B. Hyoid bone

Rationale: The hyoid bone is a U-shaped bone located in the
neck. It is unique because it does not articulate with any other
bone; instead, it is suspended by ligaments and muscles.

6. Which of the following statements best describes
endocrine glands?

• A. They secrete chemicals into ducts

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