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HESI A2 Entrance Exam Prep 2026–2027 | 318 Practice Questions with Answers & Detailed Rationales | Math, Reading, Vocabulary, Grammar, Biology, Chemistry, Anatomy & Physiology + Comprehensive Mock Exam

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Premium HESI A2 Entrance Exam Prep 2026–2027 with 318 practice questions, correct answers, detailed rationales, HESI strategies & high-yield pearls. Covers Math, Reading, Vocabulary, Grammar, Biology, Chemistry, Anatomy & Physiology plus a comprehensive mixed mock exam with tables, graphs, diagrams & data interpretation. HESI A2 ENTRANCE EXAM — COMPLETE 2026–2027 REVIEW & PRACTICE BANK Prepare comprehensively for the HESI A2 Admission Assessment with a high-yield practice resource covering the major academic areas commonly used for nursing and health-science admission preparation. This 2026–2027 resource contains 318 numbered practice questions progressing through seven core academic sections before concluding with an integrated comprehensive mock examination. The document's official internal structure covers Mathematics, Reading Comprehension, Vocabulary & General Knowledge, Grammar, Biology, Chemistry, Anatomy & Physiology, and a Comprehensive HESI A2 Mock Exam. Its premium features include difficult/high-yield concepts, detailed answer rationales, exam strategies, tables, diagrams, sketches, graphs, data displays, clinical/real-world applications, integrated multistep reasoning, and section-by-section answer keys. VERIFIED CONTENT COVERAGE Section High-Yield Coverage Mathematics Whole numbers, fractions, decimals, percentages, ratios, proportions, algebra, metric/household conversions, military time, dosage-style calculations, tables & graphs Reading Comprehension Main idea, details, inference, summaries, author's purpose, tone, context clues, sequencing, fact vs. opinion, source evaluation & data interpretation Vocabulary & General Knowledge General vocabulary, healthcare terminology, prefixes, suffixes, roots, synonyms, antonyms, context clues & word usage Grammar Sentence structure, subject-verb agreement, pronouns, verb tense, modifiers, punctuation, possessives, capitalization, spelling & commonly confused words Biology Cell biology, macromolecules, enzymes, DNA/RNA, protein synthesis, genetics, mitosis/meiosis, cellular respiration, photosynthesis & membrane transport Chemistry Atomic structure, periodic table, bonding, reactions, acids/bases, solutions, states of matter, gases, density, redox & nuclear chemistry Anatomy & Physiology Anatomical terminology, homeostasis, tissues, body systems, hormones, circulation, respiration, digestion, urinary function & systems integration Comprehensive Mock Exam Mixed calculations, reading passages, science, tables, diagrams and data-based reasoning The file itself establishes this exact coverage. PREMIUM NEXTGEN FEATURES 318 Practice Questions Correct Answers Detailed Rationales HESI Strategy Tips High-Yield Subject Pearls Seven Core Academic Areas Comprehensive Mixed Mock Examination Calculation-Based Questions Dosage-Style Mathematics Reading Passages & Evidence Interpretation Medical Vocabulary Grammar & Editing Biology & Chemistry Applications Anatomy & Physiology Integration Tables & Data Displays Graph Interpretation Diagrams & Sketch-Based Questions Multistep Reasoning Clinical & Real-World Applications Updated 2026–2027 Presentation The bank visibly uses multistep calculations and strategy/pearl teaching—for example, its mathematics section includes fractions, proportions, conversions, dosage-style calculations and graphical interpretation. Data & Graph Interpretation This is not merely a text-only Q&A bank. The resource uses tables and graphical data; for example, Reading includes before/after tutoring statistics requiring evidence-based interpretation.

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EXAM FOR HESI A2 ENTRANCE EXAM UPDATED 2026- 2027

,HESI A2 ENTRANCE EXAM

Table of Contents

Updated 2026–2027

Section Content Area High-Yield Coverage

Whole numbers, fractions, decimals, percentages, ratios, proportions,
I Mathematics algebra, metric & household conversions, military time, dosage-style
calculations, tables and graphs

Main idea, supporting details, inference, summaries, author’s purpose,
Reading
II tone, context clues, sequencing, fact vs. opinion, source evaluation, data
Comprehension
interpretation

Vocabulary & General General and healthcare vocabulary, medical terminology, prefixes, suffixes,
III
Knowledge roots, synonyms, antonyms, context clues and word usage

Sentence structure, subject–verb agreement, pronouns, verb tense,
IV Grammar modifiers, punctuation, possessives, capitalization, spelling and commonly
confused words

Cell structure, macromolecules, enzymes, DNA/RNA, protein synthesis,
V Biology genetics, mitosis, meiosis, cellular respiration, photosynthesis and
membrane transport

Atomic structure, periodic table, bonding, chemical reactions, acids and
VI Chemistry bases, solutions, states of matter, gas behavior, density, redox and nuclear
chemistry

Anatomical terminology, homeostasis, tissues, body systems, organ
VII Anatomy & Physiology functions, hormones, circulation, respiration, digestion, urinary function
and system integration

Comprehensive HESI Mixed high-difficulty questions integrating all seven core subject areas with
VIII
A2 Mock Exam calculations, passages, tables, diagrams and data-based reasoning

Premium Exam Features

• Difficult, high-yield and commonly tested concepts

• Detailed answer rationales and exam strategies

• Tables, diagrams, sketches, graphs and data displays

• Clinical and real-world application questions

, • Integrated multistep and critical-reasoning problems

• Section-by-section answer keys

• Updated 2026–2027 comprehensive preparation



HESI A2 ENTRANCE EXAM — SECTION I: MATHEMATICS



Question 1

A supply department begins with 5,460 examination gloves. During the morning, 1,785 gloves are used. An
afternoon delivery adds 2,240 gloves, after which another 675 gloves are used. How many gloves remain?

A. 4,365
B. 4,565
C. 5,015
D. 5,240

Correct Answer: D — 5,240

Rationale:

[
5460-1785+2240-675=5240
]

HESI Strategy: Process multistep inventory problems in the exact chronological order given.

Math Pearl: Intermediate values are often included as distractors.



Question 2

Evaluate:

[
5\frac16-2\frac34
]

A. (2\frac5{12})
B. (2\frac7{12})
C. (3\frac5{12})
D. (2\frac14)

Correct Answer: A — (2\frac5{12})

Rationale:

,[
5\frac16=\frac{31}{6}=\frac{62}{12}
]

[
2\frac34=\frac{11}{4}=\frac{33}{12}
]

[
\frac{62}{12}-\frac{33}{12}=\frac{29}{12}=2\frac5{12}
]

HESI Strategy: Convert mixed numbers to improper fractions when subtraction becomes cumbersome.



Question 3

How many (\frac9{10})-cup portions can be made from (3\frac35) cups?

A. 3
B. 4
C. 5
D. 6

Correct Answer: B — 4

Rationale:

[
3\frac35=\frac{18}{5}
]

[
\frac{18}{5}\div\frac9{10}

\frac{18}{5}\times\frac{10}{9}
=4
]

HESI Strategy: “How many portions fit into...” signals division.

Math Pearl: To divide fractions, multiply by the reciprocal.



Question 4

Calculate:

,[
18.75+6.408-9.967
]

A. 14.291
B. 15.091
C. 15.281
D. 15.191

Correct Answer: D — 15.191

Rationale:

[
18.750+6.408=25.158
]

[
25.158-9.967=15.191
]

HESI Strategy: Align decimal points before adding or subtracting.



Question 5

If 42% of a number is 126, what is the number?

A. 250
B. 280
C. 300
D. 320

Correct Answer: C — 300

Rationale:

[
0.42x=126
]

[
x=\frac{126}{0.42}=300
]

Math Pearl: When the question gives the part and asks for the whole, divide by the decimal form of the
percent.

,Question 6

A quantity decreases from 160 to 124. What is the percent decrease?

A. 22.5%
B. 28%
C. 29%
D. 36%

Correct Answer: A — 22.5%

Rationale:

[
160-124=36
]

[
\frac{36}{160}\times100=22.5%
]

HESI Strategy: Percent change uses the original amount as the denominator.



Question 7

The ratio of licensed nurses to nursing assistants is 5:7. If there are 96 staff members altogether, how many
are nursing assistants?

Nurses : Assistants

5 : 7



■■■■■ | ■■■■■■■

12 ratio units

A. 35
B. 40
C. 48
D. 56

Correct Answer: D — 56

Rationale:

[
5+7=12
]

,[
96\div12=8
]

[
7(8)=56
]

HESI Strategy: When a total is given, add the ratio parts first.



Question 8

Solve the proportion.

[
\frac8{15}=\frac{x}{45}
]

A. 18
B. 20
C. 24
D. 30

Correct Answer: C — 24

Rationale:

[
15x=8(45)
]

[
15x=360
]

[
x=24
]



Question 9

Which package has the lowest unit price?

Package Quantity Price

A 12 oz $4.08

,Package Quantity Price

B 18 oz $5.94

C 24 oz $7.68

D 30 oz $9.30

A. Package A
B. Package B
C. Package C
D. Package D

Correct Answer: D

Rationale:

• A: $0.34/oz

• B: $0.33/oz

• C: $0.32/oz

• D: $0.31/oz

HESI Strategy: Divide price by quantity when comparing different package sizes.



Question 10

Convert (0.0042) kilograms to grams.

A. 4.2 g
B. 42 g
C. 0.42 g
D. 420 g

Correct Answer: A — 4.2 g

Rationale:

[
0.0042\times1000=4.2
]

kg ─────────→ g

×1000

Math Pearl: (1\text{ kg}=1000\text{ g}).

,Question 11

How many teaspoons are equivalent to (5\frac12) tablespoons?

A. 11 tsp
B. 16.5 tsp
C. 18 tsp
D. 22 tsp

Correct Answer: B — 16.5 tsp

Rationale:

[
1\text{ tbsp}=3\text{ tsp}
]

[
5.5(3)=16.5
]



Question 12

A container holds (2\frac34) gallons. How many cups does it hold?

A. 22 cups
B. 32 cups
C. 36 cups
D. 44 cups

Correct Answer: D — 44 cups

Rationale:

[
1\text{ gal}=4\text{ qt}=16\text{ cups}
]

[
2.75(16)=44
]

1 gallon

↓ ×4

4 quarts

↓ ×4

, 16 cups



Question 13

Solve:

[
7x-11=45
]

A. 8
B. 7
C. 9
D. 10

Correct Answer: A — 8

Rationale:

[
7x=56
]

[
x=8
]



Question 14

Solve for (x).

[
3(x+4)=5x-8
]

A. 6
B. 8
C. 9
D. 10

Correct Answer: D — 10

Rationale:

[
3x+12=5x-8
]

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