2026 HESI PHARMACOLOGY PAPER ACTUAL
QUESTIONS AND ANSWERS SURE A+
✔✔A nurse is planning a teaching session for a client newly prescribed a miotic drug for
the treatment of glaucoma. Which information should the nurse include in the teaching
session?
A. The medication enhances the aqueous humor outflow
B. The medication inhibits the aqueous humor production
C. The medication dilates the pupils
D. The medication prevents extraocular infection - ✔✔A
✔✔The healthcare provider (HCP) prescribes a medication for an older adult client who
is reporting insomnia, and the HCP instructs the client to return in two weeks. The nurse
should question which prescription?
A Zolpidem (Ambien) 10 milligrams orally at bedtime
B. Eszopiclone (Lunesta) 10 milligrams orally at bedtime
C. Temazepam (Restoril) 7.5 milligrams orally at bedtime
D. Ramelteon (Rozerem) 8 milligrams orally at bedtime - ✔✔B
✔✔A client is diagnosed with peptic ulcer disease and receives a prescription for
esomeprazole (Nexium) 20 mg capsule daily. When providing this client with discharge
teaching, the nurse should include which instruction?
A. Drink fluids between meals to relieve gastric distress
B. Monitor for an increase in blood pressure during therapy
C. Dissolve capsule contents in fruit juice for easier ingestion
D. Take at same time each day one hour before eating a meal - ✔✔D
✔✔A client receives a new prescription for ciprofloxacin (Cipro), a synthetic quinolone.
When teaching about this drug, which information in the client history requires special
emphasis by the nurse?
, A. Snacks on dairy products such as yogurt or ice cream
B. Previously had a mild allergic reaction to a cephalosporin
C. Consumes alcoholic drinks occasionally on the weekends
D. works twenty hours a week as a lifeguard at the local pool - ✔✔D
✔✔The nurse administers the initial dose of a fentanyl (Duragesic) transdermal patch to
a client. Which assessment finding should the nurse use to evaluate the effectiveness of
the medication?
A. The absence of seizures
B. The increase in lactation
C. The presence of bowel sounds
D. The number on the numeric pain scale - ✔✔D
✔✔Based on the blood culture and sensitivity results, the healthcare provider prescribes
an IV aminoglycoside antibiotic and discontinues the current prescription for another
broad spectrum antibiotic. The medication administration record indicates that the client
received the broad spectrum antibiotic two hours ago. Which action should the nurse
implement?
A. Obtain peak and trough serum levels so the aminoglycoside antibiotic can be initiated
B. Administer the initial dose of the aminoglycoside antibiotic as soon as possible
C. Withhold antibiotic administration until the healthcare provider clarifies the
prescriptions
D. Schedule the initial dose of the aminoglycoside antibiotic for the following day - ✔✔B
✔✔The nurse is providing medication teaching for a client who recently received a
prescription for clozapine (Clozaril). Which instruction should be included in this client's
teaching plan?
A. Avoid prolonged sun exposure
B. Rise slowly from a lying position
C. Do not eat any aged cheese
D. Take as needed for anxiety - ✔✔B
✔✔A client receives a new prescription for nitroglycerin (Nitrostat) tablets. Which
instruction should the nurse include in this client's teaching?
A. Take the medication at least an hour before every meal
B. Monitor your pulse for 60 seconds before administration
C. Place under the tongue as needed every 5 minutes up to 3 times
D. REsume normal activities after chest pain relief is obtained - ✔✔C
QUESTIONS AND ANSWERS SURE A+
✔✔A nurse is planning a teaching session for a client newly prescribed a miotic drug for
the treatment of glaucoma. Which information should the nurse include in the teaching
session?
A. The medication enhances the aqueous humor outflow
B. The medication inhibits the aqueous humor production
C. The medication dilates the pupils
D. The medication prevents extraocular infection - ✔✔A
✔✔The healthcare provider (HCP) prescribes a medication for an older adult client who
is reporting insomnia, and the HCP instructs the client to return in two weeks. The nurse
should question which prescription?
A Zolpidem (Ambien) 10 milligrams orally at bedtime
B. Eszopiclone (Lunesta) 10 milligrams orally at bedtime
C. Temazepam (Restoril) 7.5 milligrams orally at bedtime
D. Ramelteon (Rozerem) 8 milligrams orally at bedtime - ✔✔B
✔✔A client is diagnosed with peptic ulcer disease and receives a prescription for
esomeprazole (Nexium) 20 mg capsule daily. When providing this client with discharge
teaching, the nurse should include which instruction?
A. Drink fluids between meals to relieve gastric distress
B. Monitor for an increase in blood pressure during therapy
C. Dissolve capsule contents in fruit juice for easier ingestion
D. Take at same time each day one hour before eating a meal - ✔✔D
✔✔A client receives a new prescription for ciprofloxacin (Cipro), a synthetic quinolone.
When teaching about this drug, which information in the client history requires special
emphasis by the nurse?
, A. Snacks on dairy products such as yogurt or ice cream
B. Previously had a mild allergic reaction to a cephalosporin
C. Consumes alcoholic drinks occasionally on the weekends
D. works twenty hours a week as a lifeguard at the local pool - ✔✔D
✔✔The nurse administers the initial dose of a fentanyl (Duragesic) transdermal patch to
a client. Which assessment finding should the nurse use to evaluate the effectiveness of
the medication?
A. The absence of seizures
B. The increase in lactation
C. The presence of bowel sounds
D. The number on the numeric pain scale - ✔✔D
✔✔Based on the blood culture and sensitivity results, the healthcare provider prescribes
an IV aminoglycoside antibiotic and discontinues the current prescription for another
broad spectrum antibiotic. The medication administration record indicates that the client
received the broad spectrum antibiotic two hours ago. Which action should the nurse
implement?
A. Obtain peak and trough serum levels so the aminoglycoside antibiotic can be initiated
B. Administer the initial dose of the aminoglycoside antibiotic as soon as possible
C. Withhold antibiotic administration until the healthcare provider clarifies the
prescriptions
D. Schedule the initial dose of the aminoglycoside antibiotic for the following day - ✔✔B
✔✔The nurse is providing medication teaching for a client who recently received a
prescription for clozapine (Clozaril). Which instruction should be included in this client's
teaching plan?
A. Avoid prolonged sun exposure
B. Rise slowly from a lying position
C. Do not eat any aged cheese
D. Take as needed for anxiety - ✔✔B
✔✔A client receives a new prescription for nitroglycerin (Nitrostat) tablets. Which
instruction should the nurse include in this client's teaching?
A. Take the medication at least an hour before every meal
B. Monitor your pulse for 60 seconds before administration
C. Place under the tongue as needed every 5 minutes up to 3 times
D. REsume normal activities after chest pain relief is obtained - ✔✔C
