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NR574/ NR 574 Final Exam (Latest 2026/2027 Update) | Complete Exam Questions with Verified Answers and Detailed Rationales | Advanced Pathophysiology & Acute Care - Hematology | A+ Graded | Chamberlain University

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INSTANT PDF DOWNLOAD - This is the comprehensive Final Exam study guide for NR574 Acute Care Practicum I at Chamberlain University (Latest 2026/2027 Update), featuring 100% verified questions and answers with detailed rationales. Designed for AGACNP students mastering advanced pathophysiology and acute care hematology to achieve an A+ Grade. Aligned with Chamberlain NR574 curriculum and AACN Acute Care Nurse Practitioner Core Competencies. This resource covers all hematology topics including: acute hemorrhage (PRBC transfusion alone does not replace plasma/clotting factors leading to coagulopathy, need for FFP/cryoprecipitate/platelets based on massive transfusion protocol) ; bleeding disorders (Hemophilia A/B/C, Von Willebrand disease, ITP isolated thrombocytopenia) ; heparin-induced thrombocytopenia (HIT - antibodies against heparin-PF4 complexes, 4Ts score, stop heparin, direct thrombin inhibitor - argatroban/bivalirudin) ; disseminated intravascular coagulation (DIC - widespread clotting and subsequent bleeding from consumption of clotting factors, treat underlying cause, supportive care) ; hematologic malignancies (acute myeloid leukemia AML - fatigue, fever, bruising, confirmed by bone marrow biopsy; chronic myeloid leukemia CML - Philadelphia chromosome, tyrosine kinase inhibitors - imatinib/Gleevec, stages: chronic, accelerated, blast crisis; acute lymphocytic leukemia ALL - lymphoblasts in bone marrow; Hodgkin lymphoma - Reed-Sternberg cells, staging, bilateral involvement indicates more advanced disease; Non-Hodgkin lymphoma) ; anemia in acutely ill patients (most common hematologic problem, differentiate types, interpret thromboelastogram) ; febrile neutropenia (oncologic emergency, temp 100.4°F + ANC 1000, treat as sepsis, broad spectrum antibiotics after cultures, most common cause of nonmalignant death) ; transfusion reactions (monitoring, recognition, management); and oncologic emergencies (tumor lysis syndrome - fluids, allopurinol, rasburicase; hypercalcemia of malignancy - hydration, bisphosphonates; superior vena cava syndrome - facial edema, dyspnea, radiation/stenting; spinal cord compression - progressive back pain, neurologic deficits, emergent MRI, dexamethasone) . INSTANT DIGITAL DOWNLOAD (PDF) immediately upon purchase. Fully text-searchable, printable, and accessible anytime. Each question includes verified answers with detailed rationales. Trusted by Chamberlain AGACNP students for NR574 Final Exam success. 100% satisfaction guarantee. NR574 Final Exam Chamberlain NR 574 Acute Care Practicum I Hematology Acute Hemorrhage PRBC Transfusion Coagulopathy Massive Transfusion Protocol HIT Heparin Induced Thrombocytopenia 4Ts Score Argatroban DIC Disseminated Intravascular Coagulation Consumptive Coagulopathy Acute Myeloid Leukemia AML Bone Marrow Biopsy Fatigue Fever Bruising Chronic Myeloid Leukemia CML Philadelphia Chromosome Imatinib Gleevec CML Stages Chronic Accelerated Blast Crisis Acute Lymphocytic Leukemia ALL Lymphoblasts Hodgkin Lymphoma Reed Sternberg Cells Staging Bilateral Involvement Non Hodgkin Lymphoma Hemophilia A B C Von Willebrand Disease ITP Isolated Thrombocytopenia Anemia Acutely Ill Patients Thromboelastogram TEG Febrile Neutropenia ANC 1000 Temp 100.4F Sepsis Emergency Tumor Lysis Syndrome Rasburicase Allopurinol Hyperuricemia Hypercalcemia Malignancy Bisphosphonates Pamidronate Zoledronic Acid Superior Vena Cava Syndrome SVCS Facial Edema Dyspnea Spinal Cord Compression Oncologic Emergency Dexamethasone AGACNP Certification Review 2026 Chamberlain NR574 Test Bank NR574 Final Exam A+ Graded Acute Care Hematology Study Guide

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NR 574 Final Exam: (Latest 2026/2027 Update) Advanced Pathophysiology &
Acute Care - Hematology, Trauma, Burns, Neurology | Q&A | Grade A | 100%
Correct (Verified Answers) – Chamberlain University

Subject: Advanced Pathophysiology & Acute Care – Rhabdomyolysis, Bowel Obstruction, SVCS,
Mesenteric Ischemia, Hepatic Steatosis, HIV, Lymphoma, Leukemia, Hemophilia, DIC, HIT, Burns, TBI,
Spinal Cord Injury, Pelvic Fractures, Compartment Syndrome
Source: NR 574 Final Exam / Chamberlain University / Clinical Practice Guidelines (2026/2027 Update)
Format: Q&A Guide with Clinical Rationales | Grade A Guaranteed


1. How often should a CK level be drawn and why?
Correct Answer: At least every 6-12 hours to establish a peak level and then subsequently a downward
trend.

1. CK rises 2-12 hours after muscle injury, peaks at 24-72 hours.
2. Trending CK helps monitor disease progression and treatment response.

2. Sylvie is a 26-year-old who presents after a marathon with dark urine, lightheadedness, nausea,
and leg weakness. The AGACNP suspects rhabdomyolysis. Which test is needed to confirm the
diagnosis?
Correct Answer: Serum creatine kinase (CK) - markedly elevated (>1000 IU/L).

1. CK is the most reliable test for rhabdomyolysis.
2. Normal CK is 45-260 IU/L.

3. Sylvie's EKG shows markedly elevated T waves and prolongation of the PR and QRS intervals.
The AGACNP should anticipate which of the following results?
Correct Answer: Hyperkalemia

1. Peaked T waves are classic for hyperkalemia.
2. Muscle breakdown releases potassium into bloodstream.

4. What is the initial management of a rhabdomyolysis patient?
Correct Answer: FLUIDS & electrolyte maintenance. Isotonic sodium chloride fluid initiated ASAP at
400 mL/hr, titrate to maintain urine output >200 mL/hr.

1. Aggressive hydration prevents acute kidney injury.
2. Goal urine output >200 mL/hr or 0.5-1.5 mL/kg/hr.

, 5. What are risk factors for acute intestinal obstruction?
Correct Answer: Adhesions from previous abdominal surgery, hernias, foreign bodies, feces,
congenital issues, trauma, inflammation, neoplasms, endometriosis, volvulus, ischemic injury,
intussusception, intraperitoneal abscess.

1. Adhesions are the most common cause of SBO.
2. Hernias are the second most common cause.

6. What diagnostic imaging should be used for bowel obstruction?
Correct Answer: Plain film x-ray - reveals dilated loops of bowel and visible air-fluid levels.

1. Barium is contraindicated in high-grade or complete obstruction.
2. Retained barium can cause concretions requiring surgical intervention.

7. Treatment of bowel obstruction includes?
Correct Answer: Gen surg consult, NG tube (intermittent suction) for decompression, fluid
resuscitation, electrolyte management. Complete obstruction requires immediate surgical intervention.

1. NG decompression reduces distention and prevents vomiting/aspiration.
2. Fluid resuscitation corrects dehydration and electrolyte imbalances.

8. What is responsible for the majority of SVCS cases?
Correct Answer: Malignant tumors, such as lung cancer, lymphoma, and metastatic tumors.

1. Lung cancer (especially SCLC) is the most common cause.
2. SVCS is a clinical emergency requiring prompt diagnosis and treatment.

9. Treatment of SVCS includes?
Correct Answer: Symptomatic relief: diuretics with low sodium diet, head elevation, supplemental O2.
Radiation therapy is the primary treatment for SVCS.

1. Radiation reduces tumor burden causing obstruction.
2. Stenting may be used for emergent relief.

10. Patients with severe acute abdominal pain that seems disproportional to physical exam findings,
or that are resistant to opioid therapy, should be suspected as having?
Correct Answer: Acute Mesenteric Ischemia

1. Pain out of proportion to exam is classic for mesenteric ischemia.
2. Gold standard diagnosis: CT angiography.

11. N-acetylcysteine should be given when?
Correct Answer: 4-8 hours after ingestion if blood levels >200 ug/mL at 4 hours or >100 ug/mL at 8
hours.

1. NAC is most effective within 8-10 hours of ingestion.
2. NAC reduces severity of hepatic necrosis.

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