ALU 201 Exam (Chapter 3) – Accurate Solutions For
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Terms in this set (75)
Risk factors for malignant melanoma race and gender: caucasion, men
sun exposure: sunburns in childhood and adult
compared to dark hair - blondes 1.8, red hair 2.4
tanning beds 1.25 risk
benign nevi-greater number & size increase risk
dysplastic nevi - found in 25-40% of people with
melanoma. increased further if family members have
lesions
histologic subtypes of mm superficial spreading melanoma
nodular melanoma
lentigo maligna
acral lentiginous melanoma
dysplastic nevi variable pigmentation
irregular outline
indistinct borders
ABCD Suspicious lesions identified by:
A = asymmetry of the lesion
B = Border irregularity
C = color variation
D = diameter greater than or equal to 6mm
superficial spreading melanoma most common subtype (60-70%) and can occur in
sun and non sun exposed areas.
, nodular melanoma 2nd most common subtype (15-30%). dark blue-black
or bluish red uniformly colored lesion. more rapid
onset and spreading than superficial spreading
melanoma.
lentigo maligna 5% of cases and generally found in older individuals.
frequently arises from pre-existing benign pigmented
lesion know as a Hutchinson freckle. generally thin
and indolent, slow.
acral lentiginous melanoma least common subtype. frequently on palm, sole,
under nail. more common in black and dark skin.
difficult to diagnose, poorer prognosis.
Breslow level depth of invasion
ulceration malignant cells extend through the skin surface layer,
metastatic potential
mitoses or dividing cells one or more detectable mitoses have significantly
reduced survival
MM prognostic factors 1. age of onset - younger/higher mortality
2. lesion location - trunk, head, neck higher mortality
3. presence of lymph node mets - most important
prognostic factors in order of importance:
a. number of positive lymph nodes
b. extent of involvement within lymph node
c. presence of ulceration in the primary lesion
4. Clark level -indicator of level of skin
a. I epidermis only
b. II upper portion of papillary dermis
c. III fills papillary dermis
d. IV reticular dermis
e. V subcutaneous fat
Every Question
Save
Terms in this set (75)
Risk factors for malignant melanoma race and gender: caucasion, men
sun exposure: sunburns in childhood and adult
compared to dark hair - blondes 1.8, red hair 2.4
tanning beds 1.25 risk
benign nevi-greater number & size increase risk
dysplastic nevi - found in 25-40% of people with
melanoma. increased further if family members have
lesions
histologic subtypes of mm superficial spreading melanoma
nodular melanoma
lentigo maligna
acral lentiginous melanoma
dysplastic nevi variable pigmentation
irregular outline
indistinct borders
ABCD Suspicious lesions identified by:
A = asymmetry of the lesion
B = Border irregularity
C = color variation
D = diameter greater than or equal to 6mm
superficial spreading melanoma most common subtype (60-70%) and can occur in
sun and non sun exposed areas.
, nodular melanoma 2nd most common subtype (15-30%). dark blue-black
or bluish red uniformly colored lesion. more rapid
onset and spreading than superficial spreading
melanoma.
lentigo maligna 5% of cases and generally found in older individuals.
frequently arises from pre-existing benign pigmented
lesion know as a Hutchinson freckle. generally thin
and indolent, slow.
acral lentiginous melanoma least common subtype. frequently on palm, sole,
under nail. more common in black and dark skin.
difficult to diagnose, poorer prognosis.
Breslow level depth of invasion
ulceration malignant cells extend through the skin surface layer,
metastatic potential
mitoses or dividing cells one or more detectable mitoses have significantly
reduced survival
MM prognostic factors 1. age of onset - younger/higher mortality
2. lesion location - trunk, head, neck higher mortality
3. presence of lymph node mets - most important
prognostic factors in order of importance:
a. number of positive lymph nodes
b. extent of involvement within lymph node
c. presence of ulceration in the primary lesion
4. Clark level -indicator of level of skin
a. I epidermis only
b. II upper portion of papillary dermis
c. III fills papillary dermis
d. IV reticular dermis
e. V subcutaneous fat
