Histology LECOM with correct answers 100%

Histology LECOM with correct answers 100% Exocytosis - Correct Answer vesicles that fuse with membrane allowing solute to leave the cell. What are the two types of Exocytosis? - Correct Answer constitutive and regulated What is difference between constitutive and regulated exocytosis? - Correct Answer Constitutive does not require a signal Regulated requires a signal What is an example of Regulated Exocytosis? - Correct Answer Insulin Release What are the types of Endocytosis? - Correct Answer 1.) Pinocytosis 2.) Phagocytosis 3.) Receptor Mediated Endocytosis What is pinocytosis? - Correct Answer A form of endocytosis, "cell drinking", non-specefic -Small proteins and fluid What is Phagocytosis? - Correct Answer A form of endocytosis, Macrophages, only specialized cells, engulf cell debris and bacteria -Actin cytoskeleton rearrangment What is and example of Receptor mediated endocytosis? - Correct Answer LDL cholesterol What components are necessary for receptor mediated endocytosis? - Correct Answer Cargo protein, receptors on the membrane, adaptin and clathrin which allow for invagination forming coated vesicle Which of the following is most likely needed for molecular oxygen (O2) to cross the plasma membrane? - Correct Answer Simple diffusion Which of the following is most likely needed for glucose molecules to enter neurons? - Correct Answer Passive transport What type of transport is involved in maintaing membrane potential? (Ex: NaK+ ATPase) - Correct Answer Active transport What are the three stages of endosomes and what pH in each respective stage? - Correct Answer 1.) Early endosomes- sort and recycle proteins, pH = 6.2-6.5 2.) Late endosomes- pre lysosomes, pH = 5.5 3.) Lysosomes- degrade, pH =4.7 What is Tay-Sachs disease? - Correct Answer Lysosomal storage disease, impacting the CNS, loss of vision, hearing. Muscle atrophy from loss of nervous tissue. -Early death (5 years old) What is a Lysosomal Storage disorder? - Correct Answer One or more enzyme is either missing or defective -Lysosomes will accumulate whatever is not bring broken down causing malfunction. A 8 month old boy has loss vision and hearing due to a genetic disorder in which Gm2 gangliosides are accumulating in his neurons. What organelle is affected by this disease? - Correct Answer Lysosomes A 8 month old boy has loss vision and hearing due to a genetic disorder in which Gm2 gangliosides are accumulating in his neurons. What is the molecular cause of this disease? - Correct Answer Lack of hexoaminidase, leading to neuronal disfunction and eventually death Rough ER - Correct Answer contains ribosomes, synthesis of secreted membrane proteins Smooth ER - Correct Answer No ribosomes, abundant in cells for: -lipid metabolism -Detoxification -Steroid synthesis (Abundant in hepatocytes) Golgi Apparatus - Correct Answer Post-translational modification, sorting and packaging of proteins Mitochondria - Correct Answer Generation of ATP Membrane system of Mitochondria - Correct Answer 2 membrane systems (both bilayers) -Inner membrane have cristae which increase surface area inside the cell. Where are mitochondria not found? - Correct Answer RBCs and terminal keratinocytes What are Nonliving Inclusions? - Correct Answer Secretory granules, store energy (glycogen and fat), Pigments Which organelle is expected to contain active proteases, lipases, nucleases and glycosidases? - Correct Answer Lysosome An infant screens positive for Zellweger syndrome. Which of the following would be affected in this patient? - Correct Answer Synthesis of plasmalogens