Lehne's Pharmacology for Nursing Care -
Elsevier 12th Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
Test Bank: Unit I – Introduction
Chapter 1: Orientation to Pharmacology
Source: Lehne's Pharmacology for Nursing Care
1. Case Study – Unfolding Clinical Judgment
A 67-year-old patient with chronic pain is prescribed oral
morphine. The nurse explains that the medication will be
absorbed through the gastrointestinal tract before entering
circulation.
Which statement best describes pharmacokinetics in this
scenario?
,A. How morphine binds to receptors to relieve pain
B. How the body absorbs, distributes, metabolizes, and excretes
morphine
C. The intensity of morphine's analgesic effects
D. The comparison of morphine with other opioids
Correct Answer: B
Rationale:
Pharmacokinetics refers to what the body does to the drug,
including absorption, distribution, metabolism, and excretion.
CJMM Phase: Recognize Cues, Analyze Cues
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
2. Case Study – Unfolding Clinical Judgment
A patient taking warfarin asks why frequent blood tests are
required.
Which explanation should the nurse provide?
A. To determine the drug’s receptor binding
B. To ensure the drug concentration remains within the
therapeutic range
C. To monitor drug taste intolerance
D. To measure the medication’s placebo effect
Correct Answer: B
,Rationale:
Monitoring ensures the drug plasma level stays within the
therapeutic range, preventing toxicity or subtherapeutic effects.
CJMM Phase: Analyze Cues, Generate Solutions
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
3. Case Study – Unfolding Clinical Judgment
A patient reports severe dizziness after starting a new
antihypertensive drug.
Which interpretation by the nurse is most appropriate?
A. This is likely a therapeutic effect
B. The symptom represents a possible adverse drug reaction
C. The drug is ineffective
D. The patient has developed drug tolerance
Correct Answer: B
Rationale:
An adverse drug reaction is any unintended or harmful
response to a medication given at normal doses.
CJMM Phase: Recognize Cues, Prioritize Hypotheses
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
, 4. Case Study – Unfolding Clinical Judgment
A nurse administers an oral medication that must pass through
the liver before reaching systemic circulation.
Which pharmacologic concept is involved?
A. Drug antagonism
B. First-pass hepatic metabolism
C. Drug tolerance
D. Potency
Correct Answer: B
Rationale:
First-pass metabolism occurs when drugs absorbed from the GI
tract are metabolized in the liver before entering systemic
circulation.
CJMM Phase: Analyze Cues
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
5. Multiple Response (SATA)
Which factors can influence drug responses in patients?
Select all that apply.
A. Age
B. Body weight
C. Genetic factors
Elsevier 12th Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
Test Bank: Unit I – Introduction
Chapter 1: Orientation to Pharmacology
Source: Lehne's Pharmacology for Nursing Care
1. Case Study – Unfolding Clinical Judgment
A 67-year-old patient with chronic pain is prescribed oral
morphine. The nurse explains that the medication will be
absorbed through the gastrointestinal tract before entering
circulation.
Which statement best describes pharmacokinetics in this
scenario?
,A. How morphine binds to receptors to relieve pain
B. How the body absorbs, distributes, metabolizes, and excretes
morphine
C. The intensity of morphine's analgesic effects
D. The comparison of morphine with other opioids
Correct Answer: B
Rationale:
Pharmacokinetics refers to what the body does to the drug,
including absorption, distribution, metabolism, and excretion.
CJMM Phase: Recognize Cues, Analyze Cues
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
2. Case Study – Unfolding Clinical Judgment
A patient taking warfarin asks why frequent blood tests are
required.
Which explanation should the nurse provide?
A. To determine the drug’s receptor binding
B. To ensure the drug concentration remains within the
therapeutic range
C. To monitor drug taste intolerance
D. To measure the medication’s placebo effect
Correct Answer: B
,Rationale:
Monitoring ensures the drug plasma level stays within the
therapeutic range, preventing toxicity or subtherapeutic effects.
CJMM Phase: Analyze Cues, Generate Solutions
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
3. Case Study – Unfolding Clinical Judgment
A patient reports severe dizziness after starting a new
antihypertensive drug.
Which interpretation by the nurse is most appropriate?
A. This is likely a therapeutic effect
B. The symptom represents a possible adverse drug reaction
C. The drug is ineffective
D. The patient has developed drug tolerance
Correct Answer: B
Rationale:
An adverse drug reaction is any unintended or harmful
response to a medication given at normal doses.
CJMM Phase: Recognize Cues, Prioritize Hypotheses
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
, 4. Case Study – Unfolding Clinical Judgment
A nurse administers an oral medication that must pass through
the liver before reaching systemic circulation.
Which pharmacologic concept is involved?
A. Drug antagonism
B. First-pass hepatic metabolism
C. Drug tolerance
D. Potency
Correct Answer: B
Rationale:
First-pass metabolism occurs when drugs absorbed from the GI
tract are metabolized in the liver before entering systemic
circulation.
CJMM Phase: Analyze Cues
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
5. Multiple Response (SATA)
Which factors can influence drug responses in patients?
Select all that apply.
A. Age
B. Body weight
C. Genetic factors
