NURS 300 EXAM 4 – Questions With
Comprehensive Solutions
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Practice questions for this set
Learn 1 /7 Study using Learn
GI bleed risk ↑
Choose an answer
What are the main classes of what happens when you block COX 1
1 2
antilipemics enzymes
3 what do niacins need to be effective 4 use of tramadol
Don't know?
Terms in this set (199)
What are the main classes of HMG-CoA (statins)
antilipemics Bile acid seqeustrants
niacin (vitamin b3)
Fibric acid derivatives (fibrates)
cholesterol absorption inhibitors
herbal agents (garlic, flax, fish oil)
,what is the first line medication usually a statin
given
why is hdl considered "good helps reduce overall total of cholesterol by removing
cholesterol" it.
what is the first line of defense when LIFESTYLE MODIFICATIONS - 6-12 months to see if
finding high cholesterol there are any changes before adding drugs because
drugs have a lot of adverse effects
atorvastatin MOA inhibits HMG-CoA reductase and lowers LDL
production while increasing HDL production - in turn
decreasing total cholesterol and triglycerides
adverse effects of atorvastatin GI issues, rash, headache, liver problems, MYOPATHY
that leads to rhabdamyolysis (muscle breakdown)
can lead to acute kidney injury.
what interacts with atorvastatin oral anticoagulants- bleeding risk
grapefruit juice
cyp3a4 drugs
when are bile acid sequestrants given in conjunction with another cholesterol lowering
drug. it is considered a 2nd line drug
Bile Acid Sequestrants moa binds to bile acids in the intestine and prevents
reabsorption. the liver then uses cholesterol to make
more bile acids and lowers the ldl levels
what are important teachings when take other medications 1 hour before or 4-6 hours
taking a bile acid sequestrant after (need to space out other medications)
an overdose can cause a bowel obstruction
encourage liquids and fiber
adverse effects of bile acid constipation, heartburn, nausea, belching, bloating
sequestrants (will improve over time)
decreased absorption of fat soluble vitamins (a, d, e,
k)
potential increase in triglycerides
, niacin mechanism of action inhibits lipoprotein synthesis in the liver and lowers
triglycerides and total cholesterol (increase HDL)
what do niacins need to be effective a higher dose
what are adverse affects of niacin flushing (caused by histamine release), pruritus, gi
distress, liver dysfunction
what is something to think of when preworkout!!! think itchiness/flushing. an nsaid can be
thinking of niacin and its adverse of relief
effects
what are contraindications for niacin liver disease, peptic ulcer disease, GOUT*,
hypertension, active bleeding
nursing tip for niacin take nsaid 30 min before to minimize flushing
gemfibrozil medication class fibric acid derivative!
gemfibrozil moa inhibits triglyceride synthesis which lowers vldls and
increases hdls up to 25%
why would you take a fibric acid hypertriglyceridemia
derivative
contraindications of gemfibrozil liver/kidney disease
gallbladder disease
adverse effects of gemfibrozil abdominal discomfort
diarrhea/nausea
blurred vision, headache
increased risk of gallstones
BONE MARROW SUPPRESSION -blood cell
production issues
what should we not take with STATINS - myalgia
gemfibrozil oral anticoagulants
Comprehensive Solutions
Save
Practice questions for this set
Learn 1 /7 Study using Learn
GI bleed risk ↑
Choose an answer
What are the main classes of what happens when you block COX 1
1 2
antilipemics enzymes
3 what do niacins need to be effective 4 use of tramadol
Don't know?
Terms in this set (199)
What are the main classes of HMG-CoA (statins)
antilipemics Bile acid seqeustrants
niacin (vitamin b3)
Fibric acid derivatives (fibrates)
cholesterol absorption inhibitors
herbal agents (garlic, flax, fish oil)
,what is the first line medication usually a statin
given
why is hdl considered "good helps reduce overall total of cholesterol by removing
cholesterol" it.
what is the first line of defense when LIFESTYLE MODIFICATIONS - 6-12 months to see if
finding high cholesterol there are any changes before adding drugs because
drugs have a lot of adverse effects
atorvastatin MOA inhibits HMG-CoA reductase and lowers LDL
production while increasing HDL production - in turn
decreasing total cholesterol and triglycerides
adverse effects of atorvastatin GI issues, rash, headache, liver problems, MYOPATHY
that leads to rhabdamyolysis (muscle breakdown)
can lead to acute kidney injury.
what interacts with atorvastatin oral anticoagulants- bleeding risk
grapefruit juice
cyp3a4 drugs
when are bile acid sequestrants given in conjunction with another cholesterol lowering
drug. it is considered a 2nd line drug
Bile Acid Sequestrants moa binds to bile acids in the intestine and prevents
reabsorption. the liver then uses cholesterol to make
more bile acids and lowers the ldl levels
what are important teachings when take other medications 1 hour before or 4-6 hours
taking a bile acid sequestrant after (need to space out other medications)
an overdose can cause a bowel obstruction
encourage liquids and fiber
adverse effects of bile acid constipation, heartburn, nausea, belching, bloating
sequestrants (will improve over time)
decreased absorption of fat soluble vitamins (a, d, e,
k)
potential increase in triglycerides
, niacin mechanism of action inhibits lipoprotein synthesis in the liver and lowers
triglycerides and total cholesterol (increase HDL)
what do niacins need to be effective a higher dose
what are adverse affects of niacin flushing (caused by histamine release), pruritus, gi
distress, liver dysfunction
what is something to think of when preworkout!!! think itchiness/flushing. an nsaid can be
thinking of niacin and its adverse of relief
effects
what are contraindications for niacin liver disease, peptic ulcer disease, GOUT*,
hypertension, active bleeding
nursing tip for niacin take nsaid 30 min before to minimize flushing
gemfibrozil medication class fibric acid derivative!
gemfibrozil moa inhibits triglyceride synthesis which lowers vldls and
increases hdls up to 25%
why would you take a fibric acid hypertriglyceridemia
derivative
contraindications of gemfibrozil liver/kidney disease
gallbladder disease
adverse effects of gemfibrozil abdominal discomfort
diarrhea/nausea
blurred vision, headache
increased risk of gallstones
BONE MARROW SUPPRESSION -blood cell
production issues
what should we not take with STATINS - myalgia
gemfibrozil oral anticoagulants
