Lehne's Pharmacology for Nursing Care -
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
Lehne’s Pharmacology for Nursing Care, 12th Edition
UNIT I: INTRODUCTION
Chapter 1: Orientation to Pharmacology
1.
A nurse explains that pharmacology is the study of which
primary concept?
A. Herbal and alternative therapies only
B. The diagnosis of disease
,C. Drugs and their interactions with living systems
D. Surgical treatment modalities
Correct Answer: C
Rationale: Pharmacology is defined as the study of drugs and
their interactions with living organisms, including therapeutic
and adverse effects.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1: Orientation to Pharmacology.
2.
Which term refers specifically to the study of what the body
does to a drug?
A. Pharmacodynamics
B. Pharmacotherapeutics
C. Pharmacokinetics
D. Toxicology
Correct Answer: C
Rationale: Pharmacokinetics describes absorption, distribution,
metabolism, and excretion—how the body acts on a drug.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1: Orientation to Pharmacology.
3.
,A drug produces the same biologic response as the body’s
endogenous substance. The nurse identifies this as a(n):
A. Antagonist
B. Partial agonist
C. Agonist
D. Competitive inhibitor
Correct Answer: C
Rationale: An agonist activates receptors and mimics the action
of endogenous compounds.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
4.
A medication binds to a receptor but does not activate it,
thereby blocking receptor activation. This drug is classified as a:
A. Full agonist
B. Antagonist
C. Potentiator
D. Synergist
Correct Answer: B
Rationale: Antagonists bind to receptors without activating
them and prevent receptor stimulation by agonists.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
, 5.
Which factor most directly influences the intensity of a drug’s
effect?
A. Drug half-life
B. Receptor occupancy
C. Route of elimination
D. Drug color
Correct Answer: B
Rationale: Drug intensity is largely determined by the number
of receptors occupied by the drug.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
6.
A nurse reviews a medication classified as having a narrow
therapeutic index. What is the priority implication?
A. The drug has minimal side effects
B. The drug is safe at any dose
C. The drug requires close monitoring
D. The drug is rarely effective
Correct Answer: C
Rationale: A narrow therapeutic index indicates a small margin
between therapeutic and toxic doses, requiring careful
monitoring.
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
Lehne’s Pharmacology for Nursing Care, 12th Edition
UNIT I: INTRODUCTION
Chapter 1: Orientation to Pharmacology
1.
A nurse explains that pharmacology is the study of which
primary concept?
A. Herbal and alternative therapies only
B. The diagnosis of disease
,C. Drugs and their interactions with living systems
D. Surgical treatment modalities
Correct Answer: C
Rationale: Pharmacology is defined as the study of drugs and
their interactions with living organisms, including therapeutic
and adverse effects.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1: Orientation to Pharmacology.
2.
Which term refers specifically to the study of what the body
does to a drug?
A. Pharmacodynamics
B. Pharmacotherapeutics
C. Pharmacokinetics
D. Toxicology
Correct Answer: C
Rationale: Pharmacokinetics describes absorption, distribution,
metabolism, and excretion—how the body acts on a drug.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1: Orientation to Pharmacology.
3.
,A drug produces the same biologic response as the body’s
endogenous substance. The nurse identifies this as a(n):
A. Antagonist
B. Partial agonist
C. Agonist
D. Competitive inhibitor
Correct Answer: C
Rationale: An agonist activates receptors and mimics the action
of endogenous compounds.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
4.
A medication binds to a receptor but does not activate it,
thereby blocking receptor activation. This drug is classified as a:
A. Full agonist
B. Antagonist
C. Potentiator
D. Synergist
Correct Answer: B
Rationale: Antagonists bind to receptors without activating
them and prevent receptor stimulation by agonists.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
, 5.
Which factor most directly influences the intensity of a drug’s
effect?
A. Drug half-life
B. Receptor occupancy
C. Route of elimination
D. Drug color
Correct Answer: B
Rationale: Drug intensity is largely determined by the number
of receptors occupied by the drug.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed., Ch.
1.
6.
A nurse reviews a medication classified as having a narrow
therapeutic index. What is the priority implication?
A. The drug has minimal side effects
B. The drug is safe at any dose
C. The drug requires close monitoring
D. The drug is rarely effective
Correct Answer: C
Rationale: A narrow therapeutic index indicates a small margin
between therapeutic and toxic doses, requiring careful
monitoring.
