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NU 641 Advanced Clinical Pharmacology Midterm Exam |Accurate |Verified

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NU 641 Advanced Clinical Pharmacology Midterm Exam |Accurate |Verified

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NU 641 Advanced Clinical Pharmacology Midterm Exam


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1 of 49

Definition



6 drugs
Interferon alfa 2 b (intron A)
Peginterferon alfa 2a (pegasys)
Lamivudine (epivir HBV)
Adefovir (hepsera)
Entecavir (baraclude)
Tenovaovir
Telbivudine (Canada only)



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Medications for managing HIV Drugs used to treat hepatitis B




Drugs used to treat hepatitis A Drugs to treat tuberculosis

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2 of 49

Definition



Lactic acidosis
Severe hepatomegaly with steatosis, headache, nausea, fatigue,
diarrhea, vomiting, fever, lymphadenopathy, pharyngitis, myalgia, rash,
hepatosplenomegaly



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Common side effects of HIV Common side effects of Antifungal
drugs medications




Common side effects of antibiotics Typical reactions of antiviral drugs


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3 of 49

Term



Anti HIV drugs that must be taken on an empty stomach



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, Abacavir Atazanavir




Sofosbuvir Efavirenz


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4 of 49

Term



Proton Pump Inhibitors (PPIs) (Omeprazole, GERD and ulcers)



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Echinocandins
Casposfungin
Voricanazole
Itraconazole
Isuvuconazonium




Fractures
Pneumonia
Acid rebound
Possible C. diff
Hypomagnesium (esp. in loop diuretics)




Caines: lidocaine, bupivacaine
Usually added with epinephrine
Decreases local blood flow and delays systemic absorption which prolongs
anesthesia and reduces risk for toxicity

, 3rd generation cephalosporin's
Cedax, suprax, ceftriaxone (Rocephin), Omnicef, spectracef, vantin, cefotaxime


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5 of 49

Term



What do you do with a known PCN allergy



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Headaches, upper respiratory infections, nasopharyngitis, and nausea
Suppresses immune function and increases risk for serious infections
Infections include pneumonia, cellulitis, bronchitis, diverticulitis, pyelonephritis, and
urinary tract infections
Report suspected infections immediately
Discontinue if infection occurs




Use with extreme caution
Most common cause of drug allergy
Do not treat with any PCN or PCN family
Treat with epinephrine (sub Q, IM, or IV)
Respiratory support
Admin drug and watch patient for 30 minutes to ensure anaphylaxis occurs.
Administer in a safe setting for first dose and monitor patient

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