PHM 350 Final Questions and Correct Answers/ Latest Update / Already Graded

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PHM 350 Final Questions and Correct
Answers/ Latest Update / Already Graded
Hair loss, GI tract, suppressed bone marrow, liver and kidney damage

Ans: Classic side effects of drugs for cancer therapy


Uses of alkylating agents

Ans: Hodgkin's disease, lymphoma, leukemia, ovarian, breast,
testicular cancers, head, neck, lung cancers, neuroblastomas,
and brain tumors.


Antimetabolites

Ans: Only work effectively in S phase of cell cycle. Substitutes
for normal substrates in DNA.


Methotrexate

Ans: Also used for Crohn's disease and ulcerative colitis


Uses of antimetabolites

Ans: Breast and colorectal cancers, osteosarcoma, leukemias,
Non-Hodgkin's lymphoma


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Mitotic inhibitors

Ans: Target microtubules so they cannot separate DNA during
replication. Can cause neuropathy. Vinblastine, vincristine, and
paclitaxel.


Steroid hormone agonist

Ans: Slows replication


Steroid hormone antagonist

Ans: Enhances replication


-tinib

Ans: Tyrosine kinase inhibitor


Monoclonal antibody

Ans: Drug meant to carry alpha radioisotope directly to
cancerous cells. Do not cause hair loss nor simply target quickly
replicating cells.




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-mab

Ans: Monoclonal antibody


Uticaria

Ans: Skin rash


Bacteriostatic

Ans: Inhibits bacterial growth


Sulfonamides and trimethoprim

Ans: Competitively block bacterial intermediary metabolism


Penicillins cephalosporins and vancomycin

Ans: Cell wall disruption, inhibition of cell wall synthesis


Erythromycin and clindamycin

Ans: Bacteriostatic inhibition of protein synthesis


Tetracyclines and aminoglycosides


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