Questions All Answered Correct 2025-
2026 Edition.
Naloxone - Answer Reversal of opioid-induced respiratory depression
N-Acetylcysteine - Answer acetaminophen antidote
Vitamin K - Answer Warfarin overdose (anticoagulant overdose)
Activated Charcoal is used for - Answer poisoning,
Adsorbs toxins in GI tract, reducing systemic absorption
Flumazenil is for what medications - Answer Benzodiazepine Antagonist
Ativan, Xanax, (Pams)
Glucagon is used for what medication oveerdoses? - Answer Beta blockers
Sodium Bicarb is used for what medication overdoses - Answer Amitriptyline, reverses TCAs
because it affects their pH
Syrup of Ipecac - Answer induces vomiting Not often used d/t risks associated w/ vomiting
3% Normal Saline is used for what conditions - Answer Hyponatremia, cerebral edema,
increased ICP
Lasix (Furosemide) is used for what conditions? - Answer increased ICP
Mannitol - Answer Used often in increased ICP patients, needs to stay warm
Salicylates overdose dx - Answer Serum salicylate level, urine ph, ABGs (more toxic if acidotic)
arterial lactate, electrolytes, glucose, PT/aPTT and CBC
,Hemodialysis
Indications: coma, renal, hepatic, pulmonary failure, pulmonary edema, severe acid-base
disturbances
Acetaminophen overdose Dx - Answer Serum acetaminophen levels, AST, ALT, PT, aPTT
Acetaminophen overdose management - Answer Activated charcoal, N-acetylcysteine,
monitor liver function, and acetaminophen
Sedatives/ hypnotics
Benzodiazepines
Barbiturates overdose Dx - Answer Medication levels
• Serum glucose to rule out hypoglycemia
• Serum and urine drug screen
• ABGs—to assess level of respiratory depression
Sedatives/ hypnotics
Benzodiazepines
Barbiturates overdose management - Answer Flumazenil, activated charcoal. Rapid ABCs, ET
tube intubation if respiratory depression severe
• Oxygen
• IV access
• Cardiac monitoring
• End tidal CO2 (i.e., capnography)
Tricyclic antidepressant amitriptyline (TCA) Dx - Answer ECG, Serum glucose level
Acetaminophen and salicylate levels to rule out co-ingestions
Tricyclic antidepressant amitriptyline (TCA) management - Answer Administer IV normal saline
fluids for hypotension
Medications
• continuous Activated charcoal
• sodium bicarbonate IV for QRS elongation
, • ABCs
• Continuous cardiac monitoring
• IV access
Beta blockers overdose Dx - Answer Serum glucose test
• Serum electrolytes—hypokalemia
• Cardiac enzymes to rule out myocardial infarction in any hemodynamically unstable patient
• ABGs
• CXR to rule out pulmonary edema
• ECG
Beta blockers overdose management - Answer Activated charcoal (see Table 70.6) to decrease
absorption
• Glucagon—antidote
• D50 if hypoglycemic
• Benzodiazepines for seizures if present
• Hemodialysis for extremely high levels
Alcohol overdose Dx - Answer Alcohol level
• Glucose to test for hypoglycemia
Alcohol overdose management - Answer IV fluids with thiamine to prevent Wernicke-
Korsakoff's syndrome—syndrome may cause seizures
• Benzodiazepines for seizures that may occur related to alcohol withdrawal
Stimulants - Answer Increase the amount of dopamine in the brain, produces euphoria,
increasing energy and alertness. Dilated pupils, everything is elevated
Stimulants examples - Answer Caffeine
Nicotine
Cocaine
Amphetamines