Wound Healing Phases and Collagen Role in Tissue Repair
1. What are the four phases of wound healing?: Hemostasis, inflammation, proliferation, and
maturation.
2. What occurs during the hemostasis phase of wound healing?: Small vessel constric-
tion, platelet aggregation, and clotting cascade activation, leading to hemostatic plugging and cessation of bleeding.
3. How does clot formation contribute to wound healing?: It provides a fibrin matrix scaffold
for subsequent healing but offers little to no tensile strength.
4. What characterizes the inflammation phase of wound healing?: Increased vascular
permeability and cellular recruitment (e.g., neutrophils, macrophages), usually lasting about 5 days.
5. What are common signs of inflammation in a wound?: Swelling, redness, and/or warmth
of the wound and surrounding tissues.
6. What happens during the proliferation phase of wound healing?: A superficial
epithelial layer forms, fibroblasts proliferate and synthesize type III collagen, and new capillaries grow.
7. What is the tensile strength of the wound during the proliferation phase?: It is
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1. What are the four phases of wound healing?: Hemostasis, inflammation, proliferation, and
maturation.
2. What occurs during the hemostasis phase of wound healing?: Small vessel constric-
tion, platelet aggregation, and clotting cascade activation, leading to hemostatic plugging and cessation of bleeding.
3. How does clot formation contribute to wound healing?: It provides a fibrin matrix scaffold
for subsequent healing but offers little to no tensile strength.
4. What characterizes the inflammation phase of wound healing?: Increased vascular
permeability and cellular recruitment (e.g., neutrophils, macrophages), usually lasting about 5 days.
5. What are common signs of inflammation in a wound?: Swelling, redness, and/or warmth
of the wound and surrounding tissues.
6. What happens during the proliferation phase of wound healing?: A superficial
epithelial layer forms, fibroblasts proliferate and synthesize type III collagen, and new capillaries grow.
7. What is the tensile strength of the wound during the proliferation phase?: It is
1/2
