Full Test Bank For_
Huether And McCance’s Understanding Pathophysiology 2nd
CANADIAN Edition
by Kelly Power-Kean, Stephanie Zettel, Mohamed Toufic El-
Hussein, Sue E. Huether, and Kathryn L. McCance.
,TABLE OF CONTENTS
Chapter 01: Cellular Biology .....................................................................................................................................4
Chapter 02: Genes And Genetic Diseases...............................................................................................................12
Chapter 03: Epigenetics And Disease .....................................................................................................................21
Chapter 04: Altered Cellular And Tissue Biology ...................................................................................................25
Chapter 05: Fluids And Electrolytes, Acids And Bases ...........................................................................................35
Chapter 06: Innate Immunity: Inflammation And Wound Healing .......................................................................44
Chapter 07: Adaptive Immunity .............................................................................................................................54
Chapter 08: Infection And Defects In Mechanisms Of Defence ............................................................................60
Chapter 09: Stress And Disease ..............................................................................................................................69
Chapter 10: Biology Of Cancer ................................................................................................................................73
Chapter 11: Cancer Epidemiology ..........................................................................................................................78
Chapter 12: Cancer In Children And Adolescents ..................................................................................................82
Chapter 13: Structure And Function Of The Neurological System ........................................................................84
Chapter 14: Pain, Temperature, Sleep, And Sensory Function ..............................................................................94
Chapter 15: Alterations In Cognitive Systems, Cerebral Hemodynamics, And Motor Function ........................104
Chapter 16: Disorders Of The Central And Peripheral Nervous Systems And Neuromuscular Junction ...........114
Chapter 17: Developmental Alterations Of Neurological Function .....................................................................125
Chapter 18: Mechanisms Of Hormonal Regulation .............................................................................................132
Chapter 19: Alterations Of Hormonal Regulation ................................................................................................140
Chapter 20: Structure And Function Of The Hematological System ...................................................................152
Chapter 21: Alterations Of Hematological Function ............................................................................................158
Chapter 22: Developmental Alterations Of Hematological Function ..................................................................173
Chapter 23: Structure And Function Of The Cardiovascular And Lymphatic Systems ........................................180
Chapter 24: Alterations Of Cardiovascular Function ...........................................................................................190
Chapter 25: Developmental Alterations Of Cardiovascular Function .................................................................208
Chapter 26: Structure And Function Of The Pulmonary System .........................................................................214
Chapter 27: Alterations Of Pulmonary Function ..................................................................................................221
Chapter 28: Developmental Alterations Of Pulmonary Function........................................................................233
Chapter 29: Structure And Function Of The Renal And Urological Systems .......................................................239
Chapter 30: Alterations Of Renal And Urinary Tract Function ............................................................................246
Chapter 31: Developmental Alterations Of Renal And Urinary Tract Function ..................................................252
Chapter 32: Structure And Function Of The Reproductive Systems ....................................................................257
Chapter 33: Alterations Of The Female Reproductive System ............................................................................265
Chapter 34: Alterations Of The Male Reproductive System ................................................................................270
Chapter 35: Structure And Function Of The Digestive System ............................................................................274
Chapter 36: Alterations Of Digestive Function.....................................................................................................281
,Chapter 37: Developmental Alterations Of Digestive Function ..........................................................................293
Chapter 38: Structure And Function Of The Musculoskeletal System ................................................................300
Chapter 39: Alterations Of Musculoskeletal Function .........................................................................................307
Chapter 40: Developmental Alterations Of Musculoskeletal Function ...............................................................316
Chapter 41: Structure, Function, And Disorders Of The Integument ..................................................................321
Chapter 42: Developmental Alterations Of The Integument ..............................................................................329
, CHAPTER 01: CELLULAR BIOLOGY
Power-Kean Et Al: Huether And Mccance’s Understanding Pathophysiology, Second Canadian Edition
MULTIPLE CHOICE
1. A Student Is Observing A Cell Under The Microscope. The Student Notices It To Have
Supercoiled DNA With Histones. What Else Would The Student Be Expected To Observe?
A. A Single Circular Chromosome
B. A Nucleus
C. Free-Floating Nuclear Material
D. No Organelles
ANS: B
The Cell Described Is A Eukaryotic Cell, So It Has Histones And A Supercoiled DNA Within Its Nucleus;
Thus, The Nucleus Should Be Observed. A Prokaryotic Cell Contains A Single Circular Chromosome And
Lacks Organelles.
DIF: Cognitive Level: Remember REF: Nucleus TOP: Physiological Integrity
2. A Nurse Is Instructing The Staff About Cellular Functions. Which Cellular Function Is The Nurse
Describing When An Isolated Cell Absorbs Oxygen And Uses It To Transform Nutrients To Energy?
A. Metabolic Absorption
B. Communication
C. Secretion
D. Respiration
ANS: D
The Cell’s Ability To Produce Energy Is Respiration. Communication Involves Maintenance Of A Steady
Dynamic State, While Metabolic Absorption Provides Cellular Nutrition, And Secretion Allows For The
Delivery Or Release Of New Substances.
DIF: Cognitive Level: Remember REF: Cellular Functions TOP: Physiological Integrity
3. A Eukaryotic Cell Is Undergoing DNA Replication. In Which Region Of The Cell Would Most Of
The Genetic Information Be Contained?
A. Peroxisomes
B. Ribosomes
C. The Nucleolus
D. Suspended In Nucleoplasm
ANS: D
The Region Of The Cell That Contains Genetic Material, Is The Nucleoplasm Contained Within The
Nucleus. The Nucleolus, Contained Within The Nucleus, Is Largely Composed Of Ribosomes.
Peroxisomes Contain Digestive Enzymes.
DIF: Cognitive Level: Remember REF: Nucleus TOP: Physiological Integrity
4. Which Of The Following Can Remove Proteins Attached To The Cell’s Bilayer By Dissolving The
Layer Itself?
A. Peripheral Membrane Proteins
B. Integral Membrane Proteins
C. Glycoproteins
D. Cell Adhesion Molecules
Huether And McCance’s Understanding Pathophysiology 2nd
CANADIAN Edition
by Kelly Power-Kean, Stephanie Zettel, Mohamed Toufic El-
Hussein, Sue E. Huether, and Kathryn L. McCance.
,TABLE OF CONTENTS
Chapter 01: Cellular Biology .....................................................................................................................................4
Chapter 02: Genes And Genetic Diseases...............................................................................................................12
Chapter 03: Epigenetics And Disease .....................................................................................................................21
Chapter 04: Altered Cellular And Tissue Biology ...................................................................................................25
Chapter 05: Fluids And Electrolytes, Acids And Bases ...........................................................................................35
Chapter 06: Innate Immunity: Inflammation And Wound Healing .......................................................................44
Chapter 07: Adaptive Immunity .............................................................................................................................54
Chapter 08: Infection And Defects In Mechanisms Of Defence ............................................................................60
Chapter 09: Stress And Disease ..............................................................................................................................69
Chapter 10: Biology Of Cancer ................................................................................................................................73
Chapter 11: Cancer Epidemiology ..........................................................................................................................78
Chapter 12: Cancer In Children And Adolescents ..................................................................................................82
Chapter 13: Structure And Function Of The Neurological System ........................................................................84
Chapter 14: Pain, Temperature, Sleep, And Sensory Function ..............................................................................94
Chapter 15: Alterations In Cognitive Systems, Cerebral Hemodynamics, And Motor Function ........................104
Chapter 16: Disorders Of The Central And Peripheral Nervous Systems And Neuromuscular Junction ...........114
Chapter 17: Developmental Alterations Of Neurological Function .....................................................................125
Chapter 18: Mechanisms Of Hormonal Regulation .............................................................................................132
Chapter 19: Alterations Of Hormonal Regulation ................................................................................................140
Chapter 20: Structure And Function Of The Hematological System ...................................................................152
Chapter 21: Alterations Of Hematological Function ............................................................................................158
Chapter 22: Developmental Alterations Of Hematological Function ..................................................................173
Chapter 23: Structure And Function Of The Cardiovascular And Lymphatic Systems ........................................180
Chapter 24: Alterations Of Cardiovascular Function ...........................................................................................190
Chapter 25: Developmental Alterations Of Cardiovascular Function .................................................................208
Chapter 26: Structure And Function Of The Pulmonary System .........................................................................214
Chapter 27: Alterations Of Pulmonary Function ..................................................................................................221
Chapter 28: Developmental Alterations Of Pulmonary Function........................................................................233
Chapter 29: Structure And Function Of The Renal And Urological Systems .......................................................239
Chapter 30: Alterations Of Renal And Urinary Tract Function ............................................................................246
Chapter 31: Developmental Alterations Of Renal And Urinary Tract Function ..................................................252
Chapter 32: Structure And Function Of The Reproductive Systems ....................................................................257
Chapter 33: Alterations Of The Female Reproductive System ............................................................................265
Chapter 34: Alterations Of The Male Reproductive System ................................................................................270
Chapter 35: Structure And Function Of The Digestive System ............................................................................274
Chapter 36: Alterations Of Digestive Function.....................................................................................................281
,Chapter 37: Developmental Alterations Of Digestive Function ..........................................................................293
Chapter 38: Structure And Function Of The Musculoskeletal System ................................................................300
Chapter 39: Alterations Of Musculoskeletal Function .........................................................................................307
Chapter 40: Developmental Alterations Of Musculoskeletal Function ...............................................................316
Chapter 41: Structure, Function, And Disorders Of The Integument ..................................................................321
Chapter 42: Developmental Alterations Of The Integument ..............................................................................329
, CHAPTER 01: CELLULAR BIOLOGY
Power-Kean Et Al: Huether And Mccance’s Understanding Pathophysiology, Second Canadian Edition
MULTIPLE CHOICE
1. A Student Is Observing A Cell Under The Microscope. The Student Notices It To Have
Supercoiled DNA With Histones. What Else Would The Student Be Expected To Observe?
A. A Single Circular Chromosome
B. A Nucleus
C. Free-Floating Nuclear Material
D. No Organelles
ANS: B
The Cell Described Is A Eukaryotic Cell, So It Has Histones And A Supercoiled DNA Within Its Nucleus;
Thus, The Nucleus Should Be Observed. A Prokaryotic Cell Contains A Single Circular Chromosome And
Lacks Organelles.
DIF: Cognitive Level: Remember REF: Nucleus TOP: Physiological Integrity
2. A Nurse Is Instructing The Staff About Cellular Functions. Which Cellular Function Is The Nurse
Describing When An Isolated Cell Absorbs Oxygen And Uses It To Transform Nutrients To Energy?
A. Metabolic Absorption
B. Communication
C. Secretion
D. Respiration
ANS: D
The Cell’s Ability To Produce Energy Is Respiration. Communication Involves Maintenance Of A Steady
Dynamic State, While Metabolic Absorption Provides Cellular Nutrition, And Secretion Allows For The
Delivery Or Release Of New Substances.
DIF: Cognitive Level: Remember REF: Cellular Functions TOP: Physiological Integrity
3. A Eukaryotic Cell Is Undergoing DNA Replication. In Which Region Of The Cell Would Most Of
The Genetic Information Be Contained?
A. Peroxisomes
B. Ribosomes
C. The Nucleolus
D. Suspended In Nucleoplasm
ANS: D
The Region Of The Cell That Contains Genetic Material, Is The Nucleoplasm Contained Within The
Nucleus. The Nucleolus, Contained Within The Nucleus, Is Largely Composed Of Ribosomes.
Peroxisomes Contain Digestive Enzymes.
DIF: Cognitive Level: Remember REF: Nucleus TOP: Physiological Integrity
4. Which Of The Following Can Remove Proteins Attached To The Cell’s Bilayer By Dissolving The
Layer Itself?
A. Peripheral Membrane Proteins
B. Integral Membrane Proteins
C. Glycoproteins
D. Cell Adhesion Molecules
