WGU 785 Final Exam NEWEST 2025 COMPLETE
QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+||BRAND NEW VERSION!!
3 Steps of PCR - CORRECT ANSWER- 1. Denaturation: DNA is heated to 95C to separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy and add DNA
polymerase.
3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides building a new
DNA strand.
Base Excision Repair (BER) - CORRECT ANSWER- How you repair a mutation. BER is used to repair
damage to a base caused by harmful molecules. You remove the base that is damaged and
replace it. *BER removes a single nucleotide*
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: - CORRECT ANSWER- replication. DNA polymerase proofreads
but sometimes a mismatch pair gets through. MMR removes a large section of the nucleotides
from the new DNA and DNA polymerase tries again. (Ex: C-T instead of C-A)
,Mismatch Repair corrects what kind of DNA damage? - CORRECT ANSWER- When a base is
mismatched due to errors in replication. Such as G-T instead of G-C. DNA polymerase comes by
and fixes it.
What happens when DNA polymerase binds to DNA to make RNA? - CORRECT ANSWER-
TRANSCRIPTION! DNA polymerase takes the individual nucleotides and matches them to the
parental sequences to ensure a correct pair. It must bind with RNA primer to work.
What is needed for DNA replication? - CORRECT ANSWER- DNA polymerase
Hemophilia Pedigree - Father has hemophilia, mother does not. What is the outcome for their
kids? - CORRECT ANSWER- His daughters would be carriers. This is x-link recessive.
Autosomal:
Dominant: - CORRECT ANSWER- Autosomal: males and females equally affected.
Dominant: non-carrier parents
polymerase chain reaction (PCR) - CORRECT ANSWER- The process of copying DNA in the lab. Uses
Template DNA, Nucleotides (dNTPS), DNA Polymerase, and DNA primers.
Nonsense Mutation - CORRECT ANSWER- Change in 1 nucleotide produces a STOP codon Stop=
nonsense because it is no more.
Silent Mutation - CORRECT ANSWER- Change in 1 nucleotide but codes for the same amino acid.
Silent= the change doesn't change the name of the protein
, Missense Mutation - CORRECT ANSWER- Change in 1 nucleotide leads to a code for a different amino
acid. Missense = mistake was made.
What happends during RNA splicing? - CORRECT ANSWER- During RNA splicing introns are cut out,
the remaining exons are joined together.
5'ATG AGT CTC TCT 3'
Find the DNA template strand. - CORRECT ANSWER- 3'TAC TCA GAG AGA 5'
The DNA template strand is complimentary. So start with the opposite number, then go L-R
with the complimentary letter.
5'ATG AGT CTC TCT 3'
What is the corresonding mRNA sequence? - CORRECT ANSWER- 5'AUG AGU CUC UCU 3'
This sequence is the same as the coding strand except T changes to U because it is RNA. RNA
doesn't have T.
How would a mutation from CTC to ATC affect the protein sequence? (CTC/ATC - coding strand,
AUC - mRNA strand) - CORRECT ANSWER- This will make a missense mutation because it changes the
name of the protein. (look at the chart provided.) missense = mistake
DNA replication process - CORRECT ANSWER- DNA ->Transcription -> RNA -> Translation ->
Polypeptide
Describe how you would find what ionized Alanine looks like. - CORRECT ANSWER- This is an amino
acid. Look for the "R" group. Alanine is a hydrophobic amino acid that has CH3. It is a weak
interaction. An ionized acid will have a + or - charge.
QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+||BRAND NEW VERSION!!
3 Steps of PCR - CORRECT ANSWER- 1. Denaturation: DNA is heated to 95C to separate it.
2. Annealing: reaction is cooled to 50C; primers stick to the DNA you want to copy and add DNA
polymerase.
3. Elongation: reaction heated to 70C and DNA polymerase, adding nucleotides building a new
DNA strand.
Base Excision Repair (BER) - CORRECT ANSWER- How you repair a mutation. BER is used to repair
damage to a base caused by harmful molecules. You remove the base that is damaged and
replace it. *BER removes a single nucleotide*
DNA glycolsylase - sees damaged DNA and removes it.
DNA polymerase-puts the right one back in while DNA ligase seals it.
Mismatch repair (MMR) occurs during: - CORRECT ANSWER- replication. DNA polymerase proofreads
but sometimes a mismatch pair gets through. MMR removes a large section of the nucleotides
from the new DNA and DNA polymerase tries again. (Ex: C-T instead of C-A)
,Mismatch Repair corrects what kind of DNA damage? - CORRECT ANSWER- When a base is
mismatched due to errors in replication. Such as G-T instead of G-C. DNA polymerase comes by
and fixes it.
What happens when DNA polymerase binds to DNA to make RNA? - CORRECT ANSWER-
TRANSCRIPTION! DNA polymerase takes the individual nucleotides and matches them to the
parental sequences to ensure a correct pair. It must bind with RNA primer to work.
What is needed for DNA replication? - CORRECT ANSWER- DNA polymerase
Hemophilia Pedigree - Father has hemophilia, mother does not. What is the outcome for their
kids? - CORRECT ANSWER- His daughters would be carriers. This is x-link recessive.
Autosomal:
Dominant: - CORRECT ANSWER- Autosomal: males and females equally affected.
Dominant: non-carrier parents
polymerase chain reaction (PCR) - CORRECT ANSWER- The process of copying DNA in the lab. Uses
Template DNA, Nucleotides (dNTPS), DNA Polymerase, and DNA primers.
Nonsense Mutation - CORRECT ANSWER- Change in 1 nucleotide produces a STOP codon Stop=
nonsense because it is no more.
Silent Mutation - CORRECT ANSWER- Change in 1 nucleotide but codes for the same amino acid.
Silent= the change doesn't change the name of the protein
, Missense Mutation - CORRECT ANSWER- Change in 1 nucleotide leads to a code for a different amino
acid. Missense = mistake was made.
What happends during RNA splicing? - CORRECT ANSWER- During RNA splicing introns are cut out,
the remaining exons are joined together.
5'ATG AGT CTC TCT 3'
Find the DNA template strand. - CORRECT ANSWER- 3'TAC TCA GAG AGA 5'
The DNA template strand is complimentary. So start with the opposite number, then go L-R
with the complimentary letter.
5'ATG AGT CTC TCT 3'
What is the corresonding mRNA sequence? - CORRECT ANSWER- 5'AUG AGU CUC UCU 3'
This sequence is the same as the coding strand except T changes to U because it is RNA. RNA
doesn't have T.
How would a mutation from CTC to ATC affect the protein sequence? (CTC/ATC - coding strand,
AUC - mRNA strand) - CORRECT ANSWER- This will make a missense mutation because it changes the
name of the protein. (look at the chart provided.) missense = mistake
DNA replication process - CORRECT ANSWER- DNA ->Transcription -> RNA -> Translation ->
Polypeptide
Describe how you would find what ionized Alanine looks like. - CORRECT ANSWER- This is an amino
acid. Look for the "R" group. Alanine is a hydrophobic amino acid that has CH3. It is a weak
interaction. An ionized acid will have a + or - charge.
