AORN PERIOP 101 Final Exam 2025–2026
Edition Questions with 100% Correct
Answers Graded A+
The *AORN Periop 101 Final Exam* (updated for 2025–2026)
consists of *100 multiple-choice questions* requiring an *80%
pass rate (80/100)*. It draws from the 23 modules, emphasizing
evidence-based practice (EBP), AORN Guidelines (2025 edition),
patient safety, asepsis, and professional accountability.
Questions test application via scenarios, with updates on
antimicrobial stewardship, human factors, and QSEN
competencies. The exam is open-book in training settings but
focuses on critical thinking.
## *Section 1: Asepsis & Sterile Technique (Q1–20)*
1. *Using mechanical friction when prepping will NOT aid in:*
A. Removal of resident bacteria
B. Removal of dirt and oil
C. The effectiveness of antimicrobials
D. Transient microbes only
,A | Friction removes transients/dirt; residents deeper |
2. *Povidone-iodine's mechanism of action is to:*
A. Disrupt the cell wall
B. Inhibit protein synthesis
C. Denature proteins
D. Block DNA replication
| C | Denatures microbial proteins (Skin Prep, 2025) |
3. *Hair at the operative site should be:*
A. Shaved
B. Clipped if necessary
C. Plucked
D. Left untouched
B | Clippers minimize micro abrasions (Guideline for
Preoperative Patient Skin Antisepsis) |
4. *The restricted zone in the OR suite is:*
A. Semi-restricted (scrubs required)
, B. OR room itself
C. Hallways
D. Storage areas
B | OR core: full PPE (Asepsis Guideline) |
5. *Surgical conscience means:*
A. Strict adherence to sterile technique
B. Reporting errors immediately
C. Both A and B
D. Documenting only
| C | Zero tolerance for breaches (Professional Accountability
Module 13) |
6. *When an incorrect surgical count occurs, search begins
with:*
A. Kick bucket
B. Trash
C. Incision site
D. Floor
| C | Incision site first for retained items (Counts Guideline) |
, 7. *Flash sterilization is for:*
A. Routine use
B. Emergencies only
C. Implants
D. Wrapped instruments
B | Immediate unwrapped use only (Sterilization Processing) |
8. *Event-related sterility is based on:*
A. Expiration dates
B. Packaging integrity and handling
C. Steam exposure
D. EO gas residuals
B | Handling/environment over dates (Sterile Technique) |
9. *PPE for splashing includes:*
A. Gloves only
B. Gown, mask, eye protection
C. N95 respirator
D. All of the above
D | Full barrier precautions (PPE Guideline) |
10. *Hand hygiene with alcohol rub: Minimum time?*
Edition Questions with 100% Correct
Answers Graded A+
The *AORN Periop 101 Final Exam* (updated for 2025–2026)
consists of *100 multiple-choice questions* requiring an *80%
pass rate (80/100)*. It draws from the 23 modules, emphasizing
evidence-based practice (EBP), AORN Guidelines (2025 edition),
patient safety, asepsis, and professional accountability.
Questions test application via scenarios, with updates on
antimicrobial stewardship, human factors, and QSEN
competencies. The exam is open-book in training settings but
focuses on critical thinking.
## *Section 1: Asepsis & Sterile Technique (Q1–20)*
1. *Using mechanical friction when prepping will NOT aid in:*
A. Removal of resident bacteria
B. Removal of dirt and oil
C. The effectiveness of antimicrobials
D. Transient microbes only
,A | Friction removes transients/dirt; residents deeper |
2. *Povidone-iodine's mechanism of action is to:*
A. Disrupt the cell wall
B. Inhibit protein synthesis
C. Denature proteins
D. Block DNA replication
| C | Denatures microbial proteins (Skin Prep, 2025) |
3. *Hair at the operative site should be:*
A. Shaved
B. Clipped if necessary
C. Plucked
D. Left untouched
B | Clippers minimize micro abrasions (Guideline for
Preoperative Patient Skin Antisepsis) |
4. *The restricted zone in the OR suite is:*
A. Semi-restricted (scrubs required)
, B. OR room itself
C. Hallways
D. Storage areas
B | OR core: full PPE (Asepsis Guideline) |
5. *Surgical conscience means:*
A. Strict adherence to sterile technique
B. Reporting errors immediately
C. Both A and B
D. Documenting only
| C | Zero tolerance for breaches (Professional Accountability
Module 13) |
6. *When an incorrect surgical count occurs, search begins
with:*
A. Kick bucket
B. Trash
C. Incision site
D. Floor
| C | Incision site first for retained items (Counts Guideline) |
, 7. *Flash sterilization is for:*
A. Routine use
B. Emergencies only
C. Implants
D. Wrapped instruments
B | Immediate unwrapped use only (Sterilization Processing) |
8. *Event-related sterility is based on:*
A. Expiration dates
B. Packaging integrity and handling
C. Steam exposure
D. EO gas residuals
B | Handling/environment over dates (Sterile Technique) |
9. *PPE for splashing includes:*
A. Gloves only
B. Gown, mask, eye protection
C. N95 respirator
D. All of the above
D | Full barrier precautions (PPE Guideline) |
10. *Hand hygiene with alcohol rub: Minimum time?*
