Guide with 100% Verified Answers for Exam Success
Key drugs that can cause hypothyroidism - ANSWER-"I
TALC"
Interferons
Tyrosine Kinase Inhibitors
Amiodarone
Lithium
Carbamazepine
Conditions: Hashimoto's disease
Levothyroxine IV:PO - ANSWER-0.75:1 (IV:PO)
,Full replacement dose levothyroxine - ANSWER-1.6
mcg/kg/day (IBW)
If known CAD: start with 12.5-25 mcg daily
Levothyroxine tablet colors - ANSWER-Orangutans Will
Vomit On You Right Before They Become Large Proud
Giants
25 Orange
50 White (no dye)
75 Violet
88 Olive
100 Yellow
112 Rose
125 Brown
137 Turquoise
150 Blue
175 Lilac
,200 Pink
300 Green
Drug induced causes of hyperthyroidism - ANSWER-
Iodine
Amiodarone
Interferons
Radiographic contrast media
treatment for thyroid storm - ANSWER-Antithyroid (PTU
preferred- give 1 hour before iodide)
Inorganic iodide therapy (SSKI or Lugol's)
Beta Blocker (Propranolol)
Systemic steroid (dexamethasone)
Aggressive cooling (APAP, cooling blankets, supportive
treatments)
, Hyperthyroid in pregnancy - ANSWER-Hyperthyroidism
during pregnancy should be treated with propylthiouracil
(PTU) during the first trimester then methimazole during
the second and third trimesters. Although methimazole is
a teratogen, the teratogenic effects are less during the
second and third trimesters, and PTU can cause liver
failure, which is why it is substituted out.
Cushing's syndrome - ANSWER-Adrenal gland produces
too much cortisol or exogenous steroids are taken in
doses higher than normal amounts of endogenous
cortisol
Addison's disease - ANSWER-a condition that occurs
when the adrenal glands do not produce enough cortisol;
Addisonian crisis (volume depletion and hypotension,
which can be fatal)