MSN 611 Midterm Exam With
Complete Questions And
Correct Detailed Answers
|Already Graded A+(Newest
Version!)
Histamine that is not found within mast cells functions - ANSWER-as a
neurotransmitter in the brain and is involved with neuroendocrine
control, cardiovascular functions, thermal and weight regulation, and
sleep and arousal balance
,what cells release histamine in the stomach? - ANSWER-
enterochromaffin-like (ECL) cells
Toxicity of antihistamines has been reported in incidents of interactions
with: - ANSWER-liver enzymes
Toxic effect of first-generation antihistamines - ANSWER-convulsions,
postural hypotension, and cardiac arrhythmias
Know anaphylaxis - ANSWER-
Central nervous system side effect of antihistamines in the elderly -
ANSWER-BEERs list,
Indication H2 antihistamines - ANSWER-used to inhibit secretion of
gastric cid with GI disorders
Know initial selection of antimicrobial therapy - ANSWER-
Mechanism of food-drug or drug-drug interactions with antibacterial
medications - ANSWER-
,Know multiple drug combination treatment for tuberculosis - ANSWER-
isoniazid, rifampin, pyrazinamide and ethambutol for up to 9 months
Significant clinical consequences of antifungal resistance. - ANSWER-txt
failure and changes in the prevalence of the fungal species causing
disease
Potential toxic effects of vorinostat and romidepsin and procedures
used to monitor for them. - ANSWER-myelosuppression and prolonged
QT interval- EKG, electrolyte monitor, ^ risk of DVT,
Mechanism of action of second-generation tyrosine kinase inhibitors -
ANSWER-form covalent bonds with kinase domains of the epidermal
growth factor receptors causing down-regulation of signaling, inhibiting
cell proliferation- skin toxicities associated when used for txt
Know about description of IFN-β - ANSWER-(fibroblast interferon) IFNs
are biological response modifiers w an antiviral and immunolodulatory
activity. IFN-B is released by human cells infected with certain viruses-
help create resistance to viral infections by acting on the host tissue
cells
Type of pathogen causes malaria - ANSWER-plasmodium parasite?
, Why systemic chemotherapy that is given prior to surgery or radiation is
given - ANSWER-neoadjuvant therapy is used to reduce the tumor
burden and to increase the effectiveness of the local txt (126)
Tumor lysis syndrome management in leukemia patients - ANSWER-
adequate IV hydration therapy, & give allopurinol if hyperuricemia is
anticipated (129)
Acrolein is a toxic metabolite of cyclophosphamide and ifosfamide that
can cause what - ANSWER-hemorrhagic cystitis (131)
Category of antineoplastic drugs offers an alternative when traditional
treatments fail - ANSWER-immunosuppressant antineoplastic agents
may offer an alternative (137)
Topoisomerase inhibitors target enzymes that control changes in DNA -
ANSWER-by altering the phosphodiester structure of the strands
during the normal life cycle of the cell
Effects of cholinesterase inhibitors have on the sinoatrial and
atrioventricular nodes - ANSWER-they have vagotonic effects on the SA
and AV nodes, leading to bradycardia and AV block which may
exacerbate syncope or hypotensive events
Complete Questions And
Correct Detailed Answers
|Already Graded A+(Newest
Version!)
Histamine that is not found within mast cells functions - ANSWER-as a
neurotransmitter in the brain and is involved with neuroendocrine
control, cardiovascular functions, thermal and weight regulation, and
sleep and arousal balance
,what cells release histamine in the stomach? - ANSWER-
enterochromaffin-like (ECL) cells
Toxicity of antihistamines has been reported in incidents of interactions
with: - ANSWER-liver enzymes
Toxic effect of first-generation antihistamines - ANSWER-convulsions,
postural hypotension, and cardiac arrhythmias
Know anaphylaxis - ANSWER-
Central nervous system side effect of antihistamines in the elderly -
ANSWER-BEERs list,
Indication H2 antihistamines - ANSWER-used to inhibit secretion of
gastric cid with GI disorders
Know initial selection of antimicrobial therapy - ANSWER-
Mechanism of food-drug or drug-drug interactions with antibacterial
medications - ANSWER-
,Know multiple drug combination treatment for tuberculosis - ANSWER-
isoniazid, rifampin, pyrazinamide and ethambutol for up to 9 months
Significant clinical consequences of antifungal resistance. - ANSWER-txt
failure and changes in the prevalence of the fungal species causing
disease
Potential toxic effects of vorinostat and romidepsin and procedures
used to monitor for them. - ANSWER-myelosuppression and prolonged
QT interval- EKG, electrolyte monitor, ^ risk of DVT,
Mechanism of action of second-generation tyrosine kinase inhibitors -
ANSWER-form covalent bonds with kinase domains of the epidermal
growth factor receptors causing down-regulation of signaling, inhibiting
cell proliferation- skin toxicities associated when used for txt
Know about description of IFN-β - ANSWER-(fibroblast interferon) IFNs
are biological response modifiers w an antiviral and immunolodulatory
activity. IFN-B is released by human cells infected with certain viruses-
help create resistance to viral infections by acting on the host tissue
cells
Type of pathogen causes malaria - ANSWER-plasmodium parasite?
, Why systemic chemotherapy that is given prior to surgery or radiation is
given - ANSWER-neoadjuvant therapy is used to reduce the tumor
burden and to increase the effectiveness of the local txt (126)
Tumor lysis syndrome management in leukemia patients - ANSWER-
adequate IV hydration therapy, & give allopurinol if hyperuricemia is
anticipated (129)
Acrolein is a toxic metabolite of cyclophosphamide and ifosfamide that
can cause what - ANSWER-hemorrhagic cystitis (131)
Category of antineoplastic drugs offers an alternative when traditional
treatments fail - ANSWER-immunosuppressant antineoplastic agents
may offer an alternative (137)
Topoisomerase inhibitors target enzymes that control changes in DNA -
ANSWER-by altering the phosphodiester structure of the strands
during the normal life cycle of the cell
Effects of cholinesterase inhibitors have on the sinoatrial and
atrioventricular nodes - ANSWER-they have vagotonic effects on the SA
and AV nodes, leading to bradycardia and AV block which may
exacerbate syncope or hypotensive events
