What is hematopoiesis? - Answers it's a continuous and regulated process that involves RBC production
& maturation of functional blood cells
Where does hematopoiesis occur in adults? - Answers in the bone marrow
where does hematopoiesis begin in the fetus? - Answers yolk sac
What happens in the mesoblastic phase of hematopoiesis? - Answers on the 19th day of embryonic
development
cells from the mesoderm migrate to the yolk sac where they differentiate into erthryoblasts and
angioblasts
lymphoid cells appear
What do erythroblasts produce? - Answers hemolglobin
gower 1
gower 2
portland
what happens in the hepatic phase of hematpoiesis? - Answers begins at 5-7 gestational weeks
clusters of RBCs, granulocytes, and monocytes
colonize fetal liver, thymus, spleen, placenta
at the maximum by the third month
declines after 6th month
minimal activity 1-2 weeks following birth
megakaryocytes begin
where does t cell production take place? - Answers thymus
where does b cell production take place? - Answers kidney and spleen
what happens in the medullary phase of hematopoiesis? - Answers -fifth month of fetal development
mesenchymal cells migrate into core of bone and differentiate into endothelial and reticular adventitial
cells
by the end of 24 weeks gestation-> bone marrow becomes primary site of hematopoiesis