Patho exam 4 - carefully curated, thorough study materials
pathophysiology (Portage Learning Online)
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Question 1
The coagulation cascade involves each of the following except:
Make thrombocytes
Activate the intrinsic and extrinsic pathways
Convert fibrinogen to fibrin
Convert prothrombin to thrombin
Which of the following increases the chance of clotting? Select all that
apply.
Vitamin K deficiency
Von Willebrand factor deficiency
Protein C deficiency
Thrombocytopenia- platelet number, of less than 150,000/µL, -cytocsis >450k
The three stages of homeostasis include each of the following except
Vascular constriction
Vascular dilation
Formation of platelet plug
Blood Coagulation
Question 2
Which of the following medications would decrease a person’s risk for
clotting? Select all that apply.
Heparin
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Warfarin
Vitamin K
Lovenox
A deficiency in which of the following would lead to a hypercoagulable
state? Select all that apply.
Protein C -Vit K needed for synthesis
Protein S
Factor II – Vit K needed for synthesis
Factor VII -Vit K needed for synthesis
Factor IX- Vit K needed for synthesis
Factor X -Vit K needed for synthesis
Antithrombin III
Prothrombin Vit K needed for synthesis
Question 3
Which of the following is NOT a hypercoagulable state? Select all that
apply.
Antiphospholipid antibody syndrome
Hemophilia A
Hemophilia B
Thrombocytopenia
Pregnancy
Oral contraceptive use
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Mutation of prothrombin gene
Mutation of factor V Leiden
Cancer
Which of the following is a hypercoagulable state? Select all that apply.
Hemophilia A
Congestive heart failure
Smoking
Thrombocytopenia
Postsurgical state
Question 4
Which of the following defects is associated with hemophilia A?
Deficiency of hemoglobin S
Deficiency of hemoglobin A
Defective gene in the X chromosome
Defective gene in the Y chromosome
Which of the following is FALSE of disseminated intravascular coagulation
(DIC)? Select all that apply.
Microthrombi cause vessel occlusion and tissue ischemia
It can cause multiple organ failure
Severe hemorrhage results
Obstetric disorders are the main cause of DIC
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