ASCP BOC 2025/2026 Exam Questions
with 100% Correct Answers | Latest
Update
Which enzyme catalyzes the conversion of starch to glucose and maltose?
- 🧠ANSWER ✔✔Amylase
Nephelometers measure light: - 🧠ANSWER ✔✔Scattered at a right angle to
the light path
A serum sample demonstrates an elevated result when tested with the
Jaffe reaction. This indicates: - 🧠ANSWER ✔✔Renal functional impairment
A vaginal/rectal swab is collected from a pregnant patient to screen for
group B Streptococcus colonization. What is the best medium to use for
specimen inoculation? - 🧠ANSWER ✔✔Lim Broth
When testing a patient for HIV antibody, what is used to confirm a positive
screening test? - 🧠ANSWER ✔✔Western Blot
,An isolate from a stool culture gives the following growth characteristics
and biochemical reactions:
MAC: Colorless colonies
HE agar: Yellow-Orange colonies
TSI: Acid slant/acid butt, no gas, no h2s
Urea: Positive
These screening results are consistent with which enteric pathogen? -
🧠ANSWER ✔✔Yersinia entercolitica. Yersinia produces yellow colonies on
HE because it can ferment sucrose.
When stool examination is negative, the preferred specimen for the
diagnosis of paragonimiasis is: - 🧠ANSWER ✔✔Sputum. Paragonimus
worms live in cystic cavities in the lungs. Ova may be found in sputum, or
swallowed and passed in stool.
A branching gram-positive, partially acid-fast organism is isolated from a
bronchial washing on a 63-year-old woman receiving chemotherapy. The
,organism does not hydrolyze casein, tyrosine or xanthine. The most likely
identification is: - 🧠ANSWER ✔✔Nocardia asteroides. (THINK BECAUSE
OF THE BRANCHING). It is partially acid fast and does not hydrolyze the
substrates casein, tyrosine, or xanthine.
Use of only male donors as a source of plasma intended for transfusion is
advocated to reduce which type of reaction? - 🧠ANSWER ✔✔TRALI.
TRALI is most commonly caused by donor HLA or granulocyte-specific
antibodies that react with recipient antigens, causing damage to the lung
basement membrane and bilateral pulmonary edema within 6 hours of
transfusion. Multiparous females are more likely to have antibodies than
males. Using male donors as the sole source of plasma products is a
strategy for reducing the risk of TRALI.
The result of an anti-nuclear antibody test was a titer of 1:320 with a
peripheral pattern. What best correlates with these results? - 🧠ANSWER
✔✔Anti-dsDNA Titer 1:80. and a high titer of antibodies to Sm. Peripheral
pattern reacts with the antigenic determinants of double strandedness of
DNA.
Abnormalities found in erythroleukemia include: - 🧠ANSWER
✔✔Megaloblastoid development.
3
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STATEMENT. ALL RIGHTS RESERVED
, Which factor will not interfere with the reagent strip test for leukocytes in
urine? - 🧠ANSWER ✔✔Nitrite. Nitrite is produced by bacteria, and WBCs
are found when there is a bacterial infection. If nitrite interfered with the
WBC reaction, then the dipstick would be worthless when testing patients
with UTIs.
Which locus is used to identify the gender of the individual from whom a
DNA sample is obtained? - 🧠ANSWER ✔✔Amelogenin. Amelogenin gives
different sized amplicons based on whether it is amplified from the X or Y
chromosomes, so males would have 2 bands on a gel at the amelogenin
locus, while females would have only 1.
Penicillium species is isolated from a bone marrow culture of a patient that
travelled to southeast Asia. After 7 days the isolate produces a red pigment
that diffuses into the medium. The technologist should: - 🧠ANSWER
✔✔Transfer a colony to BHI at 35 degrees. C. Penicillium marneffiei is a
dimorphic fungi that produces a diffusible red pigment.
An elevated serum iron with normal iron binding capacity is most likely
associated with: - 🧠ANSWER ✔✔Pernicious anemia. Ineffective
erythropoiesis. High iron turnover.
with 100% Correct Answers | Latest
Update
Which enzyme catalyzes the conversion of starch to glucose and maltose?
- 🧠ANSWER ✔✔Amylase
Nephelometers measure light: - 🧠ANSWER ✔✔Scattered at a right angle to
the light path
A serum sample demonstrates an elevated result when tested with the
Jaffe reaction. This indicates: - 🧠ANSWER ✔✔Renal functional impairment
A vaginal/rectal swab is collected from a pregnant patient to screen for
group B Streptococcus colonization. What is the best medium to use for
specimen inoculation? - 🧠ANSWER ✔✔Lim Broth
When testing a patient for HIV antibody, what is used to confirm a positive
screening test? - 🧠ANSWER ✔✔Western Blot
,An isolate from a stool culture gives the following growth characteristics
and biochemical reactions:
MAC: Colorless colonies
HE agar: Yellow-Orange colonies
TSI: Acid slant/acid butt, no gas, no h2s
Urea: Positive
These screening results are consistent with which enteric pathogen? -
🧠ANSWER ✔✔Yersinia entercolitica. Yersinia produces yellow colonies on
HE because it can ferment sucrose.
When stool examination is negative, the preferred specimen for the
diagnosis of paragonimiasis is: - 🧠ANSWER ✔✔Sputum. Paragonimus
worms live in cystic cavities in the lungs. Ova may be found in sputum, or
swallowed and passed in stool.
A branching gram-positive, partially acid-fast organism is isolated from a
bronchial washing on a 63-year-old woman receiving chemotherapy. The
,organism does not hydrolyze casein, tyrosine or xanthine. The most likely
identification is: - 🧠ANSWER ✔✔Nocardia asteroides. (THINK BECAUSE
OF THE BRANCHING). It is partially acid fast and does not hydrolyze the
substrates casein, tyrosine, or xanthine.
Use of only male donors as a source of plasma intended for transfusion is
advocated to reduce which type of reaction? - 🧠ANSWER ✔✔TRALI.
TRALI is most commonly caused by donor HLA or granulocyte-specific
antibodies that react with recipient antigens, causing damage to the lung
basement membrane and bilateral pulmonary edema within 6 hours of
transfusion. Multiparous females are more likely to have antibodies than
males. Using male donors as the sole source of plasma products is a
strategy for reducing the risk of TRALI.
The result of an anti-nuclear antibody test was a titer of 1:320 with a
peripheral pattern. What best correlates with these results? - 🧠ANSWER
✔✔Anti-dsDNA Titer 1:80. and a high titer of antibodies to Sm. Peripheral
pattern reacts with the antigenic determinants of double strandedness of
DNA.
Abnormalities found in erythroleukemia include: - 🧠ANSWER
✔✔Megaloblastoid development.
3
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
, Which factor will not interfere with the reagent strip test for leukocytes in
urine? - 🧠ANSWER ✔✔Nitrite. Nitrite is produced by bacteria, and WBCs
are found when there is a bacterial infection. If nitrite interfered with the
WBC reaction, then the dipstick would be worthless when testing patients
with UTIs.
Which locus is used to identify the gender of the individual from whom a
DNA sample is obtained? - 🧠ANSWER ✔✔Amelogenin. Amelogenin gives
different sized amplicons based on whether it is amplified from the X or Y
chromosomes, so males would have 2 bands on a gel at the amelogenin
locus, while females would have only 1.
Penicillium species is isolated from a bone marrow culture of a patient that
travelled to southeast Asia. After 7 days the isolate produces a red pigment
that diffuses into the medium. The technologist should: - 🧠ANSWER
✔✔Transfer a colony to BHI at 35 degrees. C. Penicillium marneffiei is a
dimorphic fungi that produces a diffusible red pigment.
An elevated serum iron with normal iron binding capacity is most likely
associated with: - 🧠ANSWER ✔✔Pernicious anemia. Ineffective
erythropoiesis. High iron turnover.
