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NR565
Final Exam: NR 565 Question Bank
(Latest ): Advanced
Pharmacology Fundamentals Chamberlain
1. What drug class is most likely to cause hypoglycemia:
Sulfonylureas, insulin, meglitinides, amylin analogues, Glinides, Glipins
2. Drug class less likley to cause hypoglycemia: Metformin, incretin
mimetics, DPP-4, TZD
3. Biguanidies ex: metformin
4. GLP-1 ex: Trulicity, Ozempic, Victoza
5. SGLT2-i ex: Invokana, Farxiga, Jardiance
6. DPP-4 ex: Januvia, onglyza, Tradjenta, Nesina
7. TZD ex: Actos, Avandia
8. Sulfonylurea ex: Glyburide, Glipizide, glimepride
9. Ratio of basal insulin to rapid acting insulin in TDD: 50% of TDD
comes from basil insulin and the other 50% comes from bolus insulin
,NR565
10. What is the carb to insulin ratio when calculatin basial insulin: 1 unit
of insulin will cover 10 carbs
11. General goal for A1c: less than 7%
12. A1c goal for older adult: 8% or less
13. When should insulin be considered: Type 1DM always. DM2 when they
require 3-drug combo therapy when basil insulin fails. To achieve tx goals
after 3-6 months, it is recommended to precede to a combo of injectable
regiment that includes insulin and possibly a GLP-1 agonist.
14. At what interval should A1c be checked: Every 3 months for unstable
DM every 6 months for stable DM
15. Contraindications to Pioglitazone (TZD): Severe HF cannot use
Milde HF use with caution
Bladder cancer
16. Treatment of Thyrotoxic Crisis (Thyroid Storm): High doses of
potassium iodine or strong iodine solution along with Methimazole
(which suppresses thyroid hormone synthesis), Beta Blocker (which
decreases HR) and additional measures such as IV fluids, glucocorticoids,
sedation and cooling
, NR565
17. s/s hypothyroidism: Dry hair
Puffy face
Goiter
Slow HR
Wt gain
Constipation
Possible infertility and increase risk of miscarriage and irregular cycles
18. S/S of hyperthyroidism: hair loss bulging eyes goiter rapid HR wt loss
diarrhea
menstrual cycle less often or with longer cycles
19. Drugs that decrease absorption of synthroid: histamines,
proton pump inhibitors, sucralfate, cholestyramine, colestipol, aluminum
containing medications like Maalox or Mylanta, tums, iron, mag salts.
20. Drugs that increase absorption of synthroid: phenytoin,
carbamazepine, rifampin, zoloft, phenobarbitol.
NR565
Final Exam: NR 565 Question Bank
(Latest ): Advanced
Pharmacology Fundamentals Chamberlain
1. What drug class is most likely to cause hypoglycemia:
Sulfonylureas, insulin, meglitinides, amylin analogues, Glinides, Glipins
2. Drug class less likley to cause hypoglycemia: Metformin, incretin
mimetics, DPP-4, TZD
3. Biguanidies ex: metformin
4. GLP-1 ex: Trulicity, Ozempic, Victoza
5. SGLT2-i ex: Invokana, Farxiga, Jardiance
6. DPP-4 ex: Januvia, onglyza, Tradjenta, Nesina
7. TZD ex: Actos, Avandia
8. Sulfonylurea ex: Glyburide, Glipizide, glimepride
9. Ratio of basal insulin to rapid acting insulin in TDD: 50% of TDD
comes from basil insulin and the other 50% comes from bolus insulin
,NR565
10. What is the carb to insulin ratio when calculatin basial insulin: 1 unit
of insulin will cover 10 carbs
11. General goal for A1c: less than 7%
12. A1c goal for older adult: 8% or less
13. When should insulin be considered: Type 1DM always. DM2 when they
require 3-drug combo therapy when basil insulin fails. To achieve tx goals
after 3-6 months, it is recommended to precede to a combo of injectable
regiment that includes insulin and possibly a GLP-1 agonist.
14. At what interval should A1c be checked: Every 3 months for unstable
DM every 6 months for stable DM
15. Contraindications to Pioglitazone (TZD): Severe HF cannot use
Milde HF use with caution
Bladder cancer
16. Treatment of Thyrotoxic Crisis (Thyroid Storm): High doses of
potassium iodine or strong iodine solution along with Methimazole
(which suppresses thyroid hormone synthesis), Beta Blocker (which
decreases HR) and additional measures such as IV fluids, glucocorticoids,
sedation and cooling
, NR565
17. s/s hypothyroidism: Dry hair
Puffy face
Goiter
Slow HR
Wt gain
Constipation
Possible infertility and increase risk of miscarriage and irregular cycles
18. S/S of hyperthyroidism: hair loss bulging eyes goiter rapid HR wt loss
diarrhea
menstrual cycle less often or with longer cycles
19. Drugs that decrease absorption of synthroid: histamines,
proton pump inhibitors, sucralfate, cholestyramine, colestipol, aluminum
containing medications like Maalox or Mylanta, tums, iron, mag salts.
20. Drugs that increase absorption of synthroid: phenytoin,
carbamazepine, rifampin, zoloft, phenobarbitol.
