BIOL 5500 Immunology Test 1 (Auburn
University, Dr. Schwartz) Final Exam
And 100% Correct Answers.
Lymphocytes - Answer B cells and T cells; active immunity
Myeloids - Answer macrophages, granulocytes, dendritic cells; innate immunity
Leukocytes - Answer cells of the immune system (lymphocytes and myeloids)
Cytokines/interleukins - Answer communication between leukocytes, amplify immune
response
Innate immune system - Answer involves macrophages, dendritic cells, etc. no memory, fast
reaction
Adaptive immune system - Answer involves B cells and T cells, has memory, slow reaction,
highly specific
Humoral - Answer type of adaptive immunity involving serum antibodies secreted by B cells
Immunoglobulin - Answer antibody
Cell-mediated - Answer type of adaptive immunity with T cells maintaining antibodies on
surface, activating macrophages or killing infected cells
Helper - Answer type of T cell that activates macrophages to kill contents
Cytotoxic - Answer type of T cell that kills infected cells
Antigen - Answer Molecule recognized by the immune system as foreign
,Epitope - Answer specific part of an antigen that is recognized by an antibody (does not
include the entire antigen)
Clonal expansion - Answer when T and B cells with the proper antigen-specific antibodies
multiply in the lymph nodes due to activation from an APC
APC - Answer antigen-presenting cell
APC - Answer dendritic cell, takes in pathogenic material, migrates from tissue to lymph nodes
and displays material to activate T and B cells
B cell - Answer lymphocyte activated by APC that produces humoral antibodies
Helper T cell - Answer lymphocyte activated by APC that activates macrophages
Cytotoxic T cell - Answer lymphocyte activated by APC that kills infected cells
Regulatory T cell - Answer lymphocyte activated by APC that prevents killing of self cells
Active - Answer type of immunity created by vaccine/infection, has specificity and memory
Passive - Answer type of immunity created by antibody transfer from an immune individual,
has specificity but no memory
Eosinophil - Answer battles multicellular parasites
Basophil - Answer produces cytokine IL-4
Mast cell - Answer releases histamine and heparin
Macrophages - Answer kill and eat pathogens
, Chemokine/cytokine receptor - Answer receptor leads to expression of toxic enzymes and kills
internalized pathogens
Complement receptor - Answer receptor that identifies opsonized pathogens, fast uptake
Opsonization - Answer covering of a pathogen with complement for easier phagocytic uptake
Neutrophil - Answer PMN cell
Neutrophil - Answer migrates from blood to infection site to phagocytose pathogens and kill
them with oxygen and nitrogen radicals
Integrin - Answer adhesion molecule on endothelial cells that grabs PMNs to slow them down
so that they will enter the infection site
Rolling phase - Answer part of PMN attraction in which PMNs moving in the blood stream are
slowed down
Diakinesis - Answer transmigration of PMNs from blood to tissue as attracted by chemokine
activation of integrins in endothelial cells
Oxidative burst - Answer when NADPH oxidase/phagocyte oxidase is activated in the
membrane of a phagosome in a PMN/neutrophil
NADPH oxidase - Answer produces peroxide, bleach, and superoxide radicals
iNOS - Answer where nitrogen-based radicals come from in neutrophil destruction of
phagocytosed material
Neutrophil net - Answer created by multiple PMNs as a trap for bacteria, will explode to
release deadly granules
University, Dr. Schwartz) Final Exam
And 100% Correct Answers.
Lymphocytes - Answer B cells and T cells; active immunity
Myeloids - Answer macrophages, granulocytes, dendritic cells; innate immunity
Leukocytes - Answer cells of the immune system (lymphocytes and myeloids)
Cytokines/interleukins - Answer communication between leukocytes, amplify immune
response
Innate immune system - Answer involves macrophages, dendritic cells, etc. no memory, fast
reaction
Adaptive immune system - Answer involves B cells and T cells, has memory, slow reaction,
highly specific
Humoral - Answer type of adaptive immunity involving serum antibodies secreted by B cells
Immunoglobulin - Answer antibody
Cell-mediated - Answer type of adaptive immunity with T cells maintaining antibodies on
surface, activating macrophages or killing infected cells
Helper - Answer type of T cell that activates macrophages to kill contents
Cytotoxic - Answer type of T cell that kills infected cells
Antigen - Answer Molecule recognized by the immune system as foreign
,Epitope - Answer specific part of an antigen that is recognized by an antibody (does not
include the entire antigen)
Clonal expansion - Answer when T and B cells with the proper antigen-specific antibodies
multiply in the lymph nodes due to activation from an APC
APC - Answer antigen-presenting cell
APC - Answer dendritic cell, takes in pathogenic material, migrates from tissue to lymph nodes
and displays material to activate T and B cells
B cell - Answer lymphocyte activated by APC that produces humoral antibodies
Helper T cell - Answer lymphocyte activated by APC that activates macrophages
Cytotoxic T cell - Answer lymphocyte activated by APC that kills infected cells
Regulatory T cell - Answer lymphocyte activated by APC that prevents killing of self cells
Active - Answer type of immunity created by vaccine/infection, has specificity and memory
Passive - Answer type of immunity created by antibody transfer from an immune individual,
has specificity but no memory
Eosinophil - Answer battles multicellular parasites
Basophil - Answer produces cytokine IL-4
Mast cell - Answer releases histamine and heparin
Macrophages - Answer kill and eat pathogens
, Chemokine/cytokine receptor - Answer receptor leads to expression of toxic enzymes and kills
internalized pathogens
Complement receptor - Answer receptor that identifies opsonized pathogens, fast uptake
Opsonization - Answer covering of a pathogen with complement for easier phagocytic uptake
Neutrophil - Answer PMN cell
Neutrophil - Answer migrates from blood to infection site to phagocytose pathogens and kill
them with oxygen and nitrogen radicals
Integrin - Answer adhesion molecule on endothelial cells that grabs PMNs to slow them down
so that they will enter the infection site
Rolling phase - Answer part of PMN attraction in which PMNs moving in the blood stream are
slowed down
Diakinesis - Answer transmigration of PMNs from blood to tissue as attracted by chemokine
activation of integrins in endothelial cells
Oxidative burst - Answer when NADPH oxidase/phagocyte oxidase is activated in the
membrane of a phagosome in a PMN/neutrophil
NADPH oxidase - Answer produces peroxide, bleach, and superoxide radicals
iNOS - Answer where nitrogen-based radicals come from in neutrophil destruction of
phagocytosed material
Neutrophil net - Answer created by multiple PMNs as a trap for bacteria, will explode to
release deadly granules
