NR546 WEEK 6 TEST YOUR
KNOWLEDGE QUIZ EXAM WITH
CORRECT ANSWERS 2025
Addiction is often driven by the client's attempts to: correct
answers >> self-medicate an underlying mental health disorder
adverse effects associated with the acute use of opioids:
correct answers >> -Itching
-Constipation
-Respiratory depression
-Urinary retention
-Sedation
Opioid medication: Morphine correct answers >> -Prototype
opioid agonist
-indicated for acute pain
-binds to opioid receptors in the CNS, inhibiting ascending pain
pathways, altering the perception & response to pain
-also produces CNS depression and potentially respiratory
depression
*may be life-threatening, especially if utilized with
benzodiazepines, CNS depressants, or alcohol
onset of action:
,-immediate release formulation is patient-dependent, with
variable absorption.
-IV is 5-10 minutes, with a duration 3-5 hours.
-Also available in controlled release formulation (MS Contin) and
extended-release morphine (Avinza).
Opioid medication: Fentanyl correct answers >> -has an
almost immediate onset of action when given IV, with a duration
of 0.5-1 hour
-More potent than morphine, but short duration of action
-the preferred opioid for those unable to tolerate morphine or
hydromorphone and in those with severe hepatic and renal
disease
-same indications as morphine and is also used frequently in
procedural sedation and general anesthesia
-Conversion between fentanyl products is NOT mcg for mcg
Opioid medication: Hydromorphone correct answers >> -
Similar opioid agonist as morphine but more potent
-Oral and parenteral doses are not equivalent (parenteral doses
up to 5 times more potent)
Opioid medication: Meperidine correct answers >> -No longer
recommended as an analgesic, and not widely available.
-Has numerous concerning adverse effects such as seizures and
delirium.
,Opioid medication: Methadone correct answers >> -Utilized
in detoxification and maintenance treatment of opioid addiction
and heroin addiction, with high variability among patients
-long acting opioid that binds to and occupies mu-opioid
receptors, reducing craving for opioids and prevents withdrawal
symptoms for 24 hours
-potential for abuse, only licensed opioid treatment programs or
licensed inpatient hospital units permitted to order and dispense
this medication
-potential for life threatening respiratory depression and QT
prolongation
-Equianalgesic conversion ratios between methadone and other
opioids are individually variable, with deaths occurring during
conversion from chronic high dose opiate history or opioid abuse
to methadone
-Discontinuation requires a wean to avoid withdrawal
-pregnant, a risk benefit ratio is necessary as fetal outcomes are
improved as compared to illicit drug use, however can have
decreased birth weight, length, head circumference and fetal
growth
Opioid medication: Ketamine correct answers >> -Medication
useful in general anesthesia and procedural sedation
-off label usage as infusions for acute pain, as both a stand-alone
treatment, as an adjunctive option with opioids, as well as an
intranasal formulation.
Opioid medication: Tramadol correct answers >> -Opioid
agonist, with similar indications and side effect profile as other
opioids, but that also blocks reuptake of serotonin and
norepinephrine.
, -Indicated for acute pain management, with added benefit for
patients with neuropathic pain and nociceptive pain.
-Has a lower risk of constipation and dependence than other
opioids, but does have risk of serotonin syndrome.
Opioid medication: Naloxone correct answers >> -pure
antagonist, with clinical indication for treatment of acute opioid
overdose.
-IV naloxone can dramatically reverse opioids, even in comatose
states
-recent widespread community availability of intramuscular and
intranasal administration options available given the prescription
and recreational opiate crisis, and related deaths. -Given the short
duration of action, patients can relapse into coma or previous
overdose state, and may need continued monitoring and
potentially further doses or constant infusion.
Opioid medication: Clonidine correct answers >> -
antihypertensive agent, and Alpha2-Adrenergic Agonist
-off-label adjunctive treatment for medically supervised opioid
withdrawal.
-Initial treatment is 0.1mg-0.2mg, with ability to repeat up to 4
doses until symptoms resolve, while assuring stability of blood
pressure and heart rate.
-Maintenance would be determined by severity of symptoms, with
treatment every 6-8 hours.
-Thought to produce analgesia at presynaptic and post junction
alpha-2 adrenoceptors in the spinal cord, with pain transmission
to the brain prevented.
KNOWLEDGE QUIZ EXAM WITH
CORRECT ANSWERS 2025
Addiction is often driven by the client's attempts to: correct
answers >> self-medicate an underlying mental health disorder
adverse effects associated with the acute use of opioids:
correct answers >> -Itching
-Constipation
-Respiratory depression
-Urinary retention
-Sedation
Opioid medication: Morphine correct answers >> -Prototype
opioid agonist
-indicated for acute pain
-binds to opioid receptors in the CNS, inhibiting ascending pain
pathways, altering the perception & response to pain
-also produces CNS depression and potentially respiratory
depression
*may be life-threatening, especially if utilized with
benzodiazepines, CNS depressants, or alcohol
onset of action:
,-immediate release formulation is patient-dependent, with
variable absorption.
-IV is 5-10 minutes, with a duration 3-5 hours.
-Also available in controlled release formulation (MS Contin) and
extended-release morphine (Avinza).
Opioid medication: Fentanyl correct answers >> -has an
almost immediate onset of action when given IV, with a duration
of 0.5-1 hour
-More potent than morphine, but short duration of action
-the preferred opioid for those unable to tolerate morphine or
hydromorphone and in those with severe hepatic and renal
disease
-same indications as morphine and is also used frequently in
procedural sedation and general anesthesia
-Conversion between fentanyl products is NOT mcg for mcg
Opioid medication: Hydromorphone correct answers >> -
Similar opioid agonist as morphine but more potent
-Oral and parenteral doses are not equivalent (parenteral doses
up to 5 times more potent)
Opioid medication: Meperidine correct answers >> -No longer
recommended as an analgesic, and not widely available.
-Has numerous concerning adverse effects such as seizures and
delirium.
,Opioid medication: Methadone correct answers >> -Utilized
in detoxification and maintenance treatment of opioid addiction
and heroin addiction, with high variability among patients
-long acting opioid that binds to and occupies mu-opioid
receptors, reducing craving for opioids and prevents withdrawal
symptoms for 24 hours
-potential for abuse, only licensed opioid treatment programs or
licensed inpatient hospital units permitted to order and dispense
this medication
-potential for life threatening respiratory depression and QT
prolongation
-Equianalgesic conversion ratios between methadone and other
opioids are individually variable, with deaths occurring during
conversion from chronic high dose opiate history or opioid abuse
to methadone
-Discontinuation requires a wean to avoid withdrawal
-pregnant, a risk benefit ratio is necessary as fetal outcomes are
improved as compared to illicit drug use, however can have
decreased birth weight, length, head circumference and fetal
growth
Opioid medication: Ketamine correct answers >> -Medication
useful in general anesthesia and procedural sedation
-off label usage as infusions for acute pain, as both a stand-alone
treatment, as an adjunctive option with opioids, as well as an
intranasal formulation.
Opioid medication: Tramadol correct answers >> -Opioid
agonist, with similar indications and side effect profile as other
opioids, but that also blocks reuptake of serotonin and
norepinephrine.
, -Indicated for acute pain management, with added benefit for
patients with neuropathic pain and nociceptive pain.
-Has a lower risk of constipation and dependence than other
opioids, but does have risk of serotonin syndrome.
Opioid medication: Naloxone correct answers >> -pure
antagonist, with clinical indication for treatment of acute opioid
overdose.
-IV naloxone can dramatically reverse opioids, even in comatose
states
-recent widespread community availability of intramuscular and
intranasal administration options available given the prescription
and recreational opiate crisis, and related deaths. -Given the short
duration of action, patients can relapse into coma or previous
overdose state, and may need continued monitoring and
potentially further doses or constant infusion.
Opioid medication: Clonidine correct answers >> -
antihypertensive agent, and Alpha2-Adrenergic Agonist
-off-label adjunctive treatment for medically supervised opioid
withdrawal.
-Initial treatment is 0.1mg-0.2mg, with ability to repeat up to 4
doses until symptoms resolve, while assuring stability of blood
pressure and heart rate.
-Maintenance would be determined by severity of symptoms, with
treatment every 6-8 hours.
-Thought to produce analgesia at presynaptic and post junction
alpha-2 adrenoceptors in the spinal cord, with pain transmission
to the brain prevented.
