CHAPTERI
C NOESINCHROMOSOMEI
chromosome mutations aberrations
Y Éfffff tree
1 total
changes e g patansyndrome 13
edwardssyndrome 18
2 parts are deleted duplicated
3 genes are rearranged 2 n sets
espray correct chromosome
polyploidy more than 2 setspresent
f sets origin autopolyploidy altopolyploidy
e g tetraploid Yn pentaploid Sn
vidization 3 sets
tiploid
NONDISJUNCTI
pairedhomologs fail todisjoinduringsegregation
allows for chromosomal variation
duringmeiosis I or I
, M MY 2n 1 S III
al mutation more survivable than monosomy
III iii but largerones can be lethal
unmasksrecessive lethal alleles IT in plants can changephenotype
haplo fficiency onecopyNOTenough
for survival e g down syndrome
3 215
parque
to diseases that affect
DSCR alone notenough
nondisjunction meiosis II
occasionally familia maternal
atempioid asfiomatetirda
p es
amphidiploide bothoriginalspecies are
known
endopolypeidy
IgnStan p p
tía
diagetesting
fetal cellsfromamnioticfluidor
amniocentesis
chorionofplacenta
ED EEG DNAfrommaternal
cultured Karyotyped to see
is aneuploidyexists
C NOESINCHROMOSOMEI
chromosome mutations aberrations
Y Éfffff tree
1 total
changes e g patansyndrome 13
edwardssyndrome 18
2 parts are deleted duplicated
3 genes are rearranged 2 n sets
espray correct chromosome
polyploidy more than 2 setspresent
f sets origin autopolyploidy altopolyploidy
e g tetraploid Yn pentaploid Sn
vidization 3 sets
tiploid
NONDISJUNCTI
pairedhomologs fail todisjoinduringsegregation
allows for chromosomal variation
duringmeiosis I or I
, M MY 2n 1 S III
al mutation more survivable than monosomy
III iii but largerones can be lethal
unmasksrecessive lethal alleles IT in plants can changephenotype
haplo fficiency onecopyNOTenough
for survival e g down syndrome
3 215
parque
to diseases that affect
DSCR alone notenough
nondisjunction meiosis II
occasionally familia maternal
atempioid asfiomatetirda
p es
amphidiploide bothoriginalspecies are
known
endopolypeidy
IgnStan p p
tía
diagetesting
fetal cellsfromamnioticfluidor
amniocentesis
chorionofplacenta
ED EEG DNAfrommaternal
cultured Karyotyped to see
is aneuploidyexists
