MOTHER'S MILK CORRECT 100%
If a drug is lipid soluble instead of fat soluble, would you be more or less concerned
about the likelihood for passage into Mother's milk? - ANSWER MORE
If a drug is not protein bound would you be concerned or not, about the drug passing
into the Mother's milk? - ANSWER CONCERNED
If the drug has a large molecular weight (>500) would you be worried about passage
into Mother's milk? - ANSWER No! I would not.
If the drug had a long half life and a small molecular weight (<200), would you be
concerned about passage into Mother's milk? - ANSWER Yes!
If a drug has a pH of 6 would you be concerned about ion trapping and about a
medication transferring into a Mother's milk? - ANSWER No
If a drug has a high milk/plasma ratio would you be concerned about the drug in a
mother's milk? - ANSWER Possibly...not always a concern. I would be more concerned
than with an alternative drug that has a low milk/plasma ratio.
Which infants are at most risk for effects of medications in their Mother's milk? -
ANSWER SGA, preterm, those born from a high risk pregnancy, or who are jaundiced
What resources are always available to access if you have a question about transfer of
medications into Mother's milk? - ANSWER Hale or Lawrence
What are some key ideas to keep in mind when considering drug exposure in the
infant? - ANSWER -If a medication is safe in infants, it likely will be safe if transferred to
the infant from the Mother's milk
-Use medication with most information regarding it's usage
-Try to schedule doses around breastfeeding, so infant is less exposed
-Try not to use long acting medications
-Always watch for symptoms and educate parents on them
Are high lead levels transferred through breastmilk? - ANSWER Yes, and they are
dangerous!
What is the half life of caffeine? - ANSWER In a newborn (6 weeks of age) approx. 100
hrs
In a baby (6 months of age) approx 6 hours