BIO 353 Exam 4 Study Guide Lecture
20 Questions and Answers 100% Pass
define cytoskeleton - ✔✔a network of filaments or tubes composed of protein subunits
and associated proteins
what are the three structural elements that constitute the cytoskeleton - ✔✔intermediate
filaments, microtubules, and actin filaments
what are the primary functions of the cytoskeleton - ✔✔cell motility, intracellular
motility, cytoplasmic order, and cell and tissue shape and support
what are the characteristics of intermediate filaments - ✔✔tough ropelike fibers, do not
bind nucleotides, form structurally non-polar filaments, provides mechanical support to
cells and tissues
what is the subunit of intermediate filaments - ✔✔intermediate filament protein
are intermediate filaments structurally polar - ✔✔no they are non-polar
do intermediate filaments have associated motor proteins - ✔✔no, they are not directly
responsible for generating intra-cellular movements
Katelyn Whitman, All Rights Reserved © 2025 1
, what is the primary function of intermediate filaments - ✔✔impart strength providing
mechanical support to cells and tissues
what are some examples of cytoskeletal structures that consist of intermediate filaments
- ✔✔keratin filaments, neurofilaments, and nuclear lamins
what is keratin - ✔✔epithelial cellular and tissue support
what is plectin - ✔✔intermediate filament accessory protein
what does plectin do - ✔✔further stabilizes and reinforces network by cross-linking
intermediate filaments into bundles and links them to microtubules, actin filaments,
and adhesive structures in desmosomes
what is epidermolysis bullosa simplex - ✔✔a rare mutation in keratin gene produces
defective filament assembly resulting in weakened keratin network; cell layer is highly
susceptible to mechanical trauma from rubbing of the skin during movement causing
non-scarring blisters disease; no cure
what are lamins - ✔✔intermediate filaments found in nuclei of all eukaryotic cells
what is the nuclear lamina - ✔✔interconnected web of filaments that underlies the inner
nuclear membrane
Katelyn Whitman, All Rights Reserved © 2025 2
20 Questions and Answers 100% Pass
define cytoskeleton - ✔✔a network of filaments or tubes composed of protein subunits
and associated proteins
what are the three structural elements that constitute the cytoskeleton - ✔✔intermediate
filaments, microtubules, and actin filaments
what are the primary functions of the cytoskeleton - ✔✔cell motility, intracellular
motility, cytoplasmic order, and cell and tissue shape and support
what are the characteristics of intermediate filaments - ✔✔tough ropelike fibers, do not
bind nucleotides, form structurally non-polar filaments, provides mechanical support to
cells and tissues
what is the subunit of intermediate filaments - ✔✔intermediate filament protein
are intermediate filaments structurally polar - ✔✔no they are non-polar
do intermediate filaments have associated motor proteins - ✔✔no, they are not directly
responsible for generating intra-cellular movements
Katelyn Whitman, All Rights Reserved © 2025 1
, what is the primary function of intermediate filaments - ✔✔impart strength providing
mechanical support to cells and tissues
what are some examples of cytoskeletal structures that consist of intermediate filaments
- ✔✔keratin filaments, neurofilaments, and nuclear lamins
what is keratin - ✔✔epithelial cellular and tissue support
what is plectin - ✔✔intermediate filament accessory protein
what does plectin do - ✔✔further stabilizes and reinforces network by cross-linking
intermediate filaments into bundles and links them to microtubules, actin filaments,
and adhesive structures in desmosomes
what is epidermolysis bullosa simplex - ✔✔a rare mutation in keratin gene produces
defective filament assembly resulting in weakened keratin network; cell layer is highly
susceptible to mechanical trauma from rubbing of the skin during movement causing
non-scarring blisters disease; no cure
what are lamins - ✔✔intermediate filaments found in nuclei of all eukaryotic cells
what is the nuclear lamina - ✔✔interconnected web of filaments that underlies the inner
nuclear membrane
Katelyn Whitman, All Rights Reserved © 2025 2
