Test Bank For Modern Blood Banking & Transfusion Practices
7th Edition By Denise M Harmening 9780803668881 Chapter 1-
29 ||Complete A+ Guide
,Chapter r1 rRBCs rand rPlatelet rPreservation: rHistorical rPerspectives rand rCurrent rTrends
Multiple rChoice
Identify rthe rchoice rthat rbest rcompletes rthe rstatement ror ranswers rthe rquestion.
1. Which rmetabolic rpathway ris rresponsible rfor rgenerating r90% rof rthe rATP rfor rthe rRBC?
a. Pentose rphosphate rshunt c. Glycolysis
b. Luebering-Rapoport rshunt d. r Methemoglobin rreductase
2. A runit rof rblood rwas rreturned rto rthe rblood rbank rbefore rit rwas rspiked. rApparently rthe rpatient’s rIV rfailed.
rThe runit rof rblood rwas routside rthe rblood rbank rfor r35 rminutes. rWhich rof rthe rstatements rbelow ris rmost
raccurate?
a. The runit rof rblood rshould rbe rdiscarded rimmediately.
b. The runit rof rblood rcan rbe rreturned rto rinventory.
c. The runit rof rblood rmust rbe rtransfused rwithin r4 rhours ror rbe rdiscarded rat rthe rend rof rthat rtime.
d. The runit rof rblood rmust rbe rtransfused rwith r24 rhours.
3. What ris rthe raverage rdiameter rof ra rplatelet?
a. 5 rto r10 rµm c. 1 rto r2 rµm
b. 2 rto r4 rµm d. r r 4 rto r6 rµm
4. In rthe rnormal rhemoglobin-oxygen rdissociation rcurve, rwhat rpercentage rof roxygen ris rreleased rto rthe
rtissues rwhen rPO2 r averages r40 rmm rHg?
a. 75% c. 100%
b. 25% d. r 50%
5. What rfactors rare rknown rto rinfluence rplatelet rmetabolism rand rfunction?
a. Storage rtemperature c. Platelet rcount
b. Initial rpH d. r All rof rthe rabove
6. Which rof rthe rfollowing rred rblood rcell rmorphologies rmay rbe rpresent ron rthe rperipheral rblood rsmear ras ra
rresult rof rloss rof rRBC rmembrane?
a. Spherocytes c. Burr rcells
b. Target rcells d. r Schistocytes
7. What rdoes rthe rterm rautologous rtransfusion rrefer rto?
a. A rparent rdonating rblood rfor rhis ror rher rchild
b. An rindividual rdonating rblood rfor ra rfriend
c. An rindividual rdonating rblood rfor ra rrelative
d. An rindividual rdonating rblood rfor rhis ror rher rown rtransfusion
8. What ris rthe rprimary rfunction rof rhemoglobin?
a. Iron rmetabolism c. Oxygen rtransport
b. Porphyrin rsynthesis d. r Signal rtransduction
9. All rof rthe rfollowing rareas rof rred rblood rcell rbiology rare rcrucial rfor rnormal rerythrocyte rsurvival r except:
a. Cellular rmetabolism. c. Site rof rthe rABO rantigen rattachment.
b. RBC rmembrane. d. r Hemoglobin rstructure.
,r 10. r What ris rthe rcorrect rbiochemical rcomposition rof rthe rRBC rmembrane?
a. 52% rprotein, r40% rlipid, r8% rcarbohydrate
b. 40% rprotein, r8% rlipid, r52% rcarbohydrate
c. 8% rprotein, r52% rlipid, r40% rcarbohydrate
d. 8% rlipid, r40% rcarbohydrate, r52% rprotein
r 11. r All rof rthe rfollowing rbiochemical rchanges rare rassociated rwith rloss rof rred rblood rcell rviability rupon rstorage
except:
a. Decreased rpH. c. Increased rATP rlevel.
b. Loss rof rred rblood rcell rfunction. d. r Decreased rglucose rconsumption.
r 12. r Which rred rblood rcell rpreservative rhas ra rstorage rtime rof r35 rdays?
a. ACD c. AS-1
b. CPDA-1 d. r r CPD
r 13. r The rRBC rmembrane ris rrelatively rpermeable rto rall rof rthe rfollowing rexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d. r Water.
r 14. rWhat rpercentage rof rplatelets ris rsequestered rin rthe rspleen ras rfunctional rreserve rafter rbeing rreleased rfrom
rthe rbone rmarrow?
a. 30% c. 10%
b. 50% d. r r 25%
r 15. r What ris rthe rmajor rbiochemical rconsideration rin rplatelet rstorage?
a. Glucose rmetabolism c. Production rof rcarbon rdioxide
b. Oxygen rsupply d. r Regulation rof rpH
r 16. rWhat rwould rthe rhemoglobin-oxygen rdissociation rcurve rdepict rin ra rpatient rexhibiting rclinical rsigns
rof ralkalosis?
a. Normal c. Shift rto rthe rright
b. Shift rto rthe rleft d. r None rof rthe rabove
r 17. r Name rthe rmain rlipid rcomponents rof ra rred rblood rcell rmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. r Glycophorin rA
r 18. r The rABO rblood rgroups rwere rdiscovered rin r1901 rby rwhom?
a. Charles rDrew c. Loutit rand rMollison
b. Karl rLandsteiner d. r Edward rLindeman
r 19. rA rstanding rorder rof rplatelets rwas rshipped rto ryour rfacility rby ryour rsupplier. rIt rwas rinadvertently rleft rin
rthe rcorner rof rthe rdepartment runtil rdiscovered r36 rhours rlater. rWhat rwould rthe rappropriate raction rbe rfor rthe
rblood rbanker?
a. If rthe rtemperature rin rthe rbox rwas r22 r+/- r2°C rand rthe rplatelet rswirl rseemed rOK, rit rwould
rbe rOK rto raccept rthe runit rinto rinventory.
b. The rplatelets rhave rfallen routside rthe rsupplier’s rquality rassurance. rThe runit rshould rbe
rdiscarded rbecause rthe rpH rhas rprobably rdropped rtoo rlow rand rplatelet ractivation rhas
rbeen rcompromised.
c. If rthe rtemperature rwas r1°C rto r6°C rand rthe rplatelet rswirl rseemed rOK, rit rwould rbe rOK rto
, accept rthe runit rinto rinventory.
d. If rthe rplatelets rappeared rOK rand rpassed rthe rplatelet rswirl rtest rafter rbeing rplaced ron
rthe ragitator, rthey rcould rbe raccepted rinto rthe rinventory.
r 20. r Which rmetabolic rpathway rpermits rthe raccumulation rof r2,3 rdiphosphoglycerate r(2,3-DPG)?
a. Glycolysis c. Pentose rphosphate rshunt
b. Luebering-Rapoport rshunt d. r Methemoglobin rreductase
r 21. r All rof rthe rfollowing rare rconsistent rwith ra r"shift rto rthe rright" rof rthe rhemoglobin-oxygen rdissociation rcurve
except:
a. Increased r2,3-DPG.
b. 50% rO2 r saturation rto rtissues.
c. Decreased r2,3-DPG.
d. Decreased rhemoglobin raffinity rfor rO2.
r 22. r What ris rthe rnormal rplatelet rcount rrange rper rcubic rmillimeter?
a. 100 rto r350 c. 50,000 rto r200,000
b. 150,000 rto r350,000 d. r 350,000 rto r500,000
r 23. r What rcryoprotective ragent ris radded rto rred rblood rcells rupon rfreezing?
a. Dextrose c. Glycerol
b. Adsol d. r All rof rthe rabove
r 24. r If rplatelets rare rto rbe rstored rfor r5 rdays ron ra rrotator, rwhat ris rthe roptimal rstorage rtemperature?
a. 1°C rto r6°C c. 35°C rto r37°C
b. 20°C rto r24°C d. r 1°C rto r10°C
r 25. r What rrole rdo rplatelets rplay rin rhemostasis?
a. Maintenance rof rvascular rintegrity
b. Initial rarrest rof rbleeding rby rplatelet rplug rformation
c. Stabilization rof rthe rhemostatic rplug
d. All rof rthe rabove
r 26. r Which rof rthe rfollowing rbest rdescribes r"integral" rmembrane rproteins?
a. Reside rat rthe rcytoplasmic rsurface rof rmembrane
b. Span rthe rentire rmembrane rsurface
c. Form rthe rred rblood rcell rcytoskeleton
d. None rof rthe rabove
r 27. r How ris rstroma-free rhemoglobin rsolution rprepared?
a. Outdated rred rblood rcells rare rconcentrated, rand rstroma ris rremoved.
b. Outdated rred rblood rcells rare rdiluted rwith rsaline, rand rstroma ris rremoved.
c. Outdated rred rblood rcells rare rlysed, rand rstroma ris rremoved.
d. None rof rthe rabove
r 28. r What ris rthe rnormal rlife rspan rof ran rRBC?
a. 100 rdays c. 120 rhours
b. 120 rdays d. r 2 rdays
r 29. r Regarding rloss rof rRBC rmembrane rdeformability, rall rof rthe rfollowing rare rtrue rexcept:
a. Increase rin rATP rlevel.
b. Decrease rin rATP rlevel.
7th Edition By Denise M Harmening 9780803668881 Chapter 1-
29 ||Complete A+ Guide
,Chapter r1 rRBCs rand rPlatelet rPreservation: rHistorical rPerspectives rand rCurrent rTrends
Multiple rChoice
Identify rthe rchoice rthat rbest rcompletes rthe rstatement ror ranswers rthe rquestion.
1. Which rmetabolic rpathway ris rresponsible rfor rgenerating r90% rof rthe rATP rfor rthe rRBC?
a. Pentose rphosphate rshunt c. Glycolysis
b. Luebering-Rapoport rshunt d. r Methemoglobin rreductase
2. A runit rof rblood rwas rreturned rto rthe rblood rbank rbefore rit rwas rspiked. rApparently rthe rpatient’s rIV rfailed.
rThe runit rof rblood rwas routside rthe rblood rbank rfor r35 rminutes. rWhich rof rthe rstatements rbelow ris rmost
raccurate?
a. The runit rof rblood rshould rbe rdiscarded rimmediately.
b. The runit rof rblood rcan rbe rreturned rto rinventory.
c. The runit rof rblood rmust rbe rtransfused rwithin r4 rhours ror rbe rdiscarded rat rthe rend rof rthat rtime.
d. The runit rof rblood rmust rbe rtransfused rwith r24 rhours.
3. What ris rthe raverage rdiameter rof ra rplatelet?
a. 5 rto r10 rµm c. 1 rto r2 rµm
b. 2 rto r4 rµm d. r r 4 rto r6 rµm
4. In rthe rnormal rhemoglobin-oxygen rdissociation rcurve, rwhat rpercentage rof roxygen ris rreleased rto rthe
rtissues rwhen rPO2 r averages r40 rmm rHg?
a. 75% c. 100%
b. 25% d. r 50%
5. What rfactors rare rknown rto rinfluence rplatelet rmetabolism rand rfunction?
a. Storage rtemperature c. Platelet rcount
b. Initial rpH d. r All rof rthe rabove
6. Which rof rthe rfollowing rred rblood rcell rmorphologies rmay rbe rpresent ron rthe rperipheral rblood rsmear ras ra
rresult rof rloss rof rRBC rmembrane?
a. Spherocytes c. Burr rcells
b. Target rcells d. r Schistocytes
7. What rdoes rthe rterm rautologous rtransfusion rrefer rto?
a. A rparent rdonating rblood rfor rhis ror rher rchild
b. An rindividual rdonating rblood rfor ra rfriend
c. An rindividual rdonating rblood rfor ra rrelative
d. An rindividual rdonating rblood rfor rhis ror rher rown rtransfusion
8. What ris rthe rprimary rfunction rof rhemoglobin?
a. Iron rmetabolism c. Oxygen rtransport
b. Porphyrin rsynthesis d. r Signal rtransduction
9. All rof rthe rfollowing rareas rof rred rblood rcell rbiology rare rcrucial rfor rnormal rerythrocyte rsurvival r except:
a. Cellular rmetabolism. c. Site rof rthe rABO rantigen rattachment.
b. RBC rmembrane. d. r Hemoglobin rstructure.
,r 10. r What ris rthe rcorrect rbiochemical rcomposition rof rthe rRBC rmembrane?
a. 52% rprotein, r40% rlipid, r8% rcarbohydrate
b. 40% rprotein, r8% rlipid, r52% rcarbohydrate
c. 8% rprotein, r52% rlipid, r40% rcarbohydrate
d. 8% rlipid, r40% rcarbohydrate, r52% rprotein
r 11. r All rof rthe rfollowing rbiochemical rchanges rare rassociated rwith rloss rof rred rblood rcell rviability rupon rstorage
except:
a. Decreased rpH. c. Increased rATP rlevel.
b. Loss rof rred rblood rcell rfunction. d. r Decreased rglucose rconsumption.
r 12. r Which rred rblood rcell rpreservative rhas ra rstorage rtime rof r35 rdays?
a. ACD c. AS-1
b. CPDA-1 d. r r CPD
r 13. r The rRBC rmembrane ris rrelatively rpermeable rto rall rof rthe rfollowing rexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d. r Water.
r 14. rWhat rpercentage rof rplatelets ris rsequestered rin rthe rspleen ras rfunctional rreserve rafter rbeing rreleased rfrom
rthe rbone rmarrow?
a. 30% c. 10%
b. 50% d. r r 25%
r 15. r What ris rthe rmajor rbiochemical rconsideration rin rplatelet rstorage?
a. Glucose rmetabolism c. Production rof rcarbon rdioxide
b. Oxygen rsupply d. r Regulation rof rpH
r 16. rWhat rwould rthe rhemoglobin-oxygen rdissociation rcurve rdepict rin ra rpatient rexhibiting rclinical rsigns
rof ralkalosis?
a. Normal c. Shift rto rthe rright
b. Shift rto rthe rleft d. r None rof rthe rabove
r 17. r Name rthe rmain rlipid rcomponents rof ra rred rblood rcell rmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. r Glycophorin rA
r 18. r The rABO rblood rgroups rwere rdiscovered rin r1901 rby rwhom?
a. Charles rDrew c. Loutit rand rMollison
b. Karl rLandsteiner d. r Edward rLindeman
r 19. rA rstanding rorder rof rplatelets rwas rshipped rto ryour rfacility rby ryour rsupplier. rIt rwas rinadvertently rleft rin
rthe rcorner rof rthe rdepartment runtil rdiscovered r36 rhours rlater. rWhat rwould rthe rappropriate raction rbe rfor rthe
rblood rbanker?
a. If rthe rtemperature rin rthe rbox rwas r22 r+/- r2°C rand rthe rplatelet rswirl rseemed rOK, rit rwould
rbe rOK rto raccept rthe runit rinto rinventory.
b. The rplatelets rhave rfallen routside rthe rsupplier’s rquality rassurance. rThe runit rshould rbe
rdiscarded rbecause rthe rpH rhas rprobably rdropped rtoo rlow rand rplatelet ractivation rhas
rbeen rcompromised.
c. If rthe rtemperature rwas r1°C rto r6°C rand rthe rplatelet rswirl rseemed rOK, rit rwould rbe rOK rto
, accept rthe runit rinto rinventory.
d. If rthe rplatelets rappeared rOK rand rpassed rthe rplatelet rswirl rtest rafter rbeing rplaced ron
rthe ragitator, rthey rcould rbe raccepted rinto rthe rinventory.
r 20. r Which rmetabolic rpathway rpermits rthe raccumulation rof r2,3 rdiphosphoglycerate r(2,3-DPG)?
a. Glycolysis c. Pentose rphosphate rshunt
b. Luebering-Rapoport rshunt d. r Methemoglobin rreductase
r 21. r All rof rthe rfollowing rare rconsistent rwith ra r"shift rto rthe rright" rof rthe rhemoglobin-oxygen rdissociation rcurve
except:
a. Increased r2,3-DPG.
b. 50% rO2 r saturation rto rtissues.
c. Decreased r2,3-DPG.
d. Decreased rhemoglobin raffinity rfor rO2.
r 22. r What ris rthe rnormal rplatelet rcount rrange rper rcubic rmillimeter?
a. 100 rto r350 c. 50,000 rto r200,000
b. 150,000 rto r350,000 d. r 350,000 rto r500,000
r 23. r What rcryoprotective ragent ris radded rto rred rblood rcells rupon rfreezing?
a. Dextrose c. Glycerol
b. Adsol d. r All rof rthe rabove
r 24. r If rplatelets rare rto rbe rstored rfor r5 rdays ron ra rrotator, rwhat ris rthe roptimal rstorage rtemperature?
a. 1°C rto r6°C c. 35°C rto r37°C
b. 20°C rto r24°C d. r 1°C rto r10°C
r 25. r What rrole rdo rplatelets rplay rin rhemostasis?
a. Maintenance rof rvascular rintegrity
b. Initial rarrest rof rbleeding rby rplatelet rplug rformation
c. Stabilization rof rthe rhemostatic rplug
d. All rof rthe rabove
r 26. r Which rof rthe rfollowing rbest rdescribes r"integral" rmembrane rproteins?
a. Reside rat rthe rcytoplasmic rsurface rof rmembrane
b. Span rthe rentire rmembrane rsurface
c. Form rthe rred rblood rcell rcytoskeleton
d. None rof rthe rabove
r 27. r How ris rstroma-free rhemoglobin rsolution rprepared?
a. Outdated rred rblood rcells rare rconcentrated, rand rstroma ris rremoved.
b. Outdated rred rblood rcells rare rdiluted rwith rsaline, rand rstroma ris rremoved.
c. Outdated rred rblood rcells rare rlysed, rand rstroma ris rremoved.
d. None rof rthe rabove
r 28. r What ris rthe rnormal rlife rspan rof ran rRBC?
a. 100 rdays c. 120 rhours
b. 120 rdays d. r 2 rdays
r 29. r Regarding rloss rof rRBC rmembrane rdeformability, rall rof rthe rfollowing rare rtrue rexcept:
a. Increase rin rATP rlevel.
b. Decrease rin rATP rlevel.
