Exam (elaborations) NURS 617 Pharm

NURS 617 Pharm (Exam 1)
Summer 2024/2025 Jean
Genzale- Latest
Questions and Answers

, Pharmacogenomics - CORRECT ANSWERS-the study of genetically determined
variations in the response to drugs

Pharmacokinetics - CORRECT ANSWERS-The way the body processes drugs.
Involves 4 processes of:
-absorption
-distribution
-metabolism
-excretion

Drug clearance - CORRECT ANSWERS-The process of metabolism and excretion/
The disappearance of the drug from the patient's serum

Absorption - CORRECT ANSWERS-The process by which drug molecules move from
their site of administration, across one or more cell membranes, in order to gain entry to
the blood

Driving force of absorption - CORRECT ANSWERS-Concentration gradient =
Concentration on either side of the membrane

Concentration Gradient - CORRECT ANSWERS-Passive diffusion- from high
concentration to low concentration. Does NOT require energy

Routes of drug administration that do NOT involve the absorption process - CORRECT
ANSWERS--IV
-Intraarterial

Absorption: Fastest to slowest drug formulations - CORRECT ANSWERS-FASTEST
-liquids
-suspensions
-powders

-capsules
-tablets
-enteric coated tablets
-sustained release tablets
SLOWEST

Factors that determine the rate and extent of drug absorption - CORRECT ANSWERS--
solubility (or dissolvability) of the drug
-physical properties of the drug
-area of absorptive surface
-blood supply at absorptive surface
-length of time of contact with absorptive surface