NSG 533 Advanced Pharmacology
Test 1 Week 4
A 22-year-old woman with SAD has significant improvement in anxiety after 14 weeks of
treatment with sertraline. How long should she remain on sertraline?
A. Discontinue now
B. Additional 3 months
C. Additional 6 months
D. Additional 1-2 years
E. Lifetime therapy - C
A 23-year-old married white woman comes to the outpatient psychiatric clinic
complaining of decreased sleep, decreased appetite, decreased concentration,
depressed
mood, thoughts of death, and lack of interest in activities for 6 weeks' duration. She has
no history of psychiatric illness and takes no medications except for Ortho-Tri Cyclen Lo
daily. Based upon the patients symptoms, choose the best medication to treat this
patient.
A. Nefazodone 100 mg po twice daily
B. Paroxetine 20 mg po daily
C. St. John's wort 300 mg po three times daily
D. Amitriptyline 25 mg at bedtime - B
A 23-year-old otherwise healthy woman with GAD has no past history of drug or alcohol
abuse and no family history of substance abuse. She is started on lorazepam 0.5 mg
three times daily. Which of the following side effects will you warn her about?
a. Risk of withdrawal symptoms upon discontinuation
b. Sedation
c. Anterograde amnesia
d. Slowed reaction time
e. All of the above - E
A 26-year-old African American man with SAD has been stable on sertraline 100
mg/day for
the past year. He reports to the clinic today with complaints of increased anxiety,
agitation, and
nausea. Upon further examination, you notice he last filled his sertraline Rx (90-day
supply) 4
months ago. Medications: Ibuprofen 400 mg as needed for joint pain. He reports taking
sertraline
most days but ran out 4 days ago. What is most likely going on with AS?
A. Serotonin syndrome
B. Serotonin withdrawal
, C. Neuroleptic malignant syndrome
D. Relapse of SAD
E. Rebound anxiety - B
A 26-year-old man with a history of depression has been taking sertraline 200 mg/day
for 12 weeks with no response. The patient has no other complications. The physician
asks for your recommendation. The most reasonable recommendation would be to:
A. Increase sertraline
B. Add fluoxetine
C. Switch to amitriptyline
D. Change to venlafaxine
E. Decrease sertraline - D
A 26-year-old patient with a first episode of depression has been treated with duloxetine
60 mg twice daily for the past 4 months. The patient would like to discontinue treatment.
The patient should be told that they need at least _____full months of antidepressant
therapy after reaching full remission.
A. 3
B. 6
C. 9
D. 12 - B
A 28-year-old man with a history of depression has been taking sertraline 200 mg daily
for 12 weeks with no response. The patient has no other complaints. The physician
asks for your recommendation. The most reasonable recommendation would be to:
A. Increase sertraline
B. Add fluoxetine
C. Switch to amitriptyline
D. Change to venlafaxine - D
A 36-year-old man is admitted to the hospital for a severe methicillin-resistant
Staphylococcus aureus diabetic foot infection and is started on linezolid 600 mg IV
every 12 hours. His medication profile includes paroxetine 40 mg every morning,
trazodone 100 mg at bedtime as needed for sleep, and metformin 1000 mg po twice
daily. After 3
days on these medications, the patient becomes agitated, confused, and diaphoretic
and develops myoclonic jerks. Which of the following is the most likely diagnosis?
A. Overdose of metformin
B. Bacterial meningitis
C. Neuroleptic malignant syndrome
D. Serotonin syndrome - D
A 38-year-old male is diagnosed with major depressive disorder by his general
practitioner. His symptoms include depressed mood, insomnia, decreased appetite, and
poor concentration. He denies suicidal ideation. The patient remembers that his mother
and brother responded well to venlafaxine in the past, and he would like to try the same
Test 1 Week 4
A 22-year-old woman with SAD has significant improvement in anxiety after 14 weeks of
treatment with sertraline. How long should she remain on sertraline?
A. Discontinue now
B. Additional 3 months
C. Additional 6 months
D. Additional 1-2 years
E. Lifetime therapy - C
A 23-year-old married white woman comes to the outpatient psychiatric clinic
complaining of decreased sleep, decreased appetite, decreased concentration,
depressed
mood, thoughts of death, and lack of interest in activities for 6 weeks' duration. She has
no history of psychiatric illness and takes no medications except for Ortho-Tri Cyclen Lo
daily. Based upon the patients symptoms, choose the best medication to treat this
patient.
A. Nefazodone 100 mg po twice daily
B. Paroxetine 20 mg po daily
C. St. John's wort 300 mg po three times daily
D. Amitriptyline 25 mg at bedtime - B
A 23-year-old otherwise healthy woman with GAD has no past history of drug or alcohol
abuse and no family history of substance abuse. She is started on lorazepam 0.5 mg
three times daily. Which of the following side effects will you warn her about?
a. Risk of withdrawal symptoms upon discontinuation
b. Sedation
c. Anterograde amnesia
d. Slowed reaction time
e. All of the above - E
A 26-year-old African American man with SAD has been stable on sertraline 100
mg/day for
the past year. He reports to the clinic today with complaints of increased anxiety,
agitation, and
nausea. Upon further examination, you notice he last filled his sertraline Rx (90-day
supply) 4
months ago. Medications: Ibuprofen 400 mg as needed for joint pain. He reports taking
sertraline
most days but ran out 4 days ago. What is most likely going on with AS?
A. Serotonin syndrome
B. Serotonin withdrawal
, C. Neuroleptic malignant syndrome
D. Relapse of SAD
E. Rebound anxiety - B
A 26-year-old man with a history of depression has been taking sertraline 200 mg/day
for 12 weeks with no response. The patient has no other complications. The physician
asks for your recommendation. The most reasonable recommendation would be to:
A. Increase sertraline
B. Add fluoxetine
C. Switch to amitriptyline
D. Change to venlafaxine
E. Decrease sertraline - D
A 26-year-old patient with a first episode of depression has been treated with duloxetine
60 mg twice daily for the past 4 months. The patient would like to discontinue treatment.
The patient should be told that they need at least _____full months of antidepressant
therapy after reaching full remission.
A. 3
B. 6
C. 9
D. 12 - B
A 28-year-old man with a history of depression has been taking sertraline 200 mg daily
for 12 weeks with no response. The patient has no other complaints. The physician
asks for your recommendation. The most reasonable recommendation would be to:
A. Increase sertraline
B. Add fluoxetine
C. Switch to amitriptyline
D. Change to venlafaxine - D
A 36-year-old man is admitted to the hospital for a severe methicillin-resistant
Staphylococcus aureus diabetic foot infection and is started on linezolid 600 mg IV
every 12 hours. His medication profile includes paroxetine 40 mg every morning,
trazodone 100 mg at bedtime as needed for sleep, and metformin 1000 mg po twice
daily. After 3
days on these medications, the patient becomes agitated, confused, and diaphoretic
and develops myoclonic jerks. Which of the following is the most likely diagnosis?
A. Overdose of metformin
B. Bacterial meningitis
C. Neuroleptic malignant syndrome
D. Serotonin syndrome - D
A 38-year-old male is diagnosed with major depressive disorder by his general
practitioner. His symptoms include depressed mood, insomnia, decreased appetite, and
poor concentration. He denies suicidal ideation. The patient remembers that his mother
and brother responded well to venlafaxine in the past, and he would like to try the same
