SKIN ANATOMY, PRESSURE INJURIES, WOUND HEALING &
MANAGEMENT 200+ PRACTICE QUESTIONS WITH DETAILED
EXPLANATIONS
1. Which structure of the skin provides the body with photoprotective
properties by absorbing harmful UV light?
A. Langerhans cells
B. Stratum lucidum
C. Melanin
D. Odland bodies
Correct Answer: C. Melanin
Explanation: Melanin is the pigment produced by melanocytes that absorbs
harmful UV radiation, protecting the skin from DNA damage. Langerhans cells
provide immune function, Odland bodies (lamellar bodies) release lipids for barrier
function, and stratum lucidum is a clear layer found only in thick skin.
2. A WCN is assessing a patient whose wounds were caused by external factors.
Which of the following is an example of this type of injury?
A. Venous Leg Ulcer
B. Eczema
C. Malignant Wound
D. Pressure Injury
,Correct Answer: D. Pressure Injury
Explanation: Pressure injuries result from mechanical factors including friction,
shear, pressure, and moisture—all external forces. Venous leg ulcers, eczema, and
malignant wounds have underlying internal or systemic etiologies rather than
purely external mechanical causes.
3. What is the best descriptor of tissue damage caused by shear strain?
A. Edema caused by impaired lymphatic function resulting from unrelieved
pressure
B. SQ tissue damaged by distortion of blood vessels
C. Superficial skin loss caused by separation of epidermal and dermal layers
D. Tissue compression caused by sustained pressure
Correct Answer: B. SQ tissue damaged by distortion of blood vessels
Explanation: Shear strain disrupts blood vessels from deeper structures, causing
deep tissue injury (DTI) as occurs with pressure injuries. This distortion of
vasculature compromises blood flow to subcutaneous tissues, leading to ischemic
damage that may not be visible on the skin surface initially.
4. Which type of wounds develop at the muscle-bone interface?
A. Friction wounds
B. Wounds caused by intertriginous dermatitis
C. Incontinence wounds
D. Pressure injuries
Correct Answer: D. Pressure injuries
Explanation: Pressure injuries typically begin at the muscle-bone interface where
tissue compression is greatest, particularly over bony prominences. The damage
progresses outward toward the skin surface, which is why pressure injuries are
often full-thickness wounds by the time they become visible.
,5. What is the initial effect of sustained pressure on a body part?
A. Tissue necrosis
B. Tissue deformation
C. Tissue loss
D. Tissue remodeling
Correct Answer: B. Tissue deformation
Explanation: Sustained pressure initially causes tissue deformation as soft tissues
are compressed between bone and an external surface. This deformation leads to
microvascular occlusion, ischemia, and ultimately necrosis if pressure is not
relieved. Tissue remodeling and loss are later consequences.
6. What is the driving force for the collection of data regarding facility-acquired
PIs?
A. Minimizing staff workload
B. Patient satisfaction
C. Quality indicators
D. Infection control
Correct Answer: C. Quality indicators
Explanation: Benchmarking of facility-acquired pressure injury rates reflects
quality of care and identifies opportunities for improvement. This data is used for
quality reporting, regulatory compliance, and performance improvement
initiatives rather than primarily for patient satisfaction, infection control, or
workload management.
7. A WCN documents a wound as being of mixed etiology. What is the nurse
describing?
, A. Patient positioning affected the development of the wound
B. The wound is limited to the superficial skin and tissue layers
C. Features of both superficial and deeper injury are manifested
D. Patient history reveals exposure to only one mechanical stressor
Correct Answer: C. Features of both superficial and deeper injury are manifested
Explanation: Mixed etiology wounds show characteristics of both superficial skin
loss (such as from friction or moisture) and evidence of deeper tissue damage
(such as from pressure or shear). This often occurs when multiple mechanical
stressors affect the same anatomical location.
8. Which assessment parameter is of greatest value to differential assessment of
wounds?
A. Type of eschar involved
B. Indicators of pressure vs indicators of maceration or friction
C. Wound size
D. Indicators of infected vs noninfected wounds
Correct Answer: B. Indicators of pressure vs indicators of maceration or friction
Explanation: Determining the source of injury is the most critical parameter in
differential wound assessment. Differentiating between pressure-related damage,
maceration, friction injuries, and other etiologies guides appropriate treatment
selection and prevention strategies.
9. Which condition might the WCN observe as an indicator of pressure injury?
A. Edema
B. Purple discoloration
C. Maceration of surrounding tissue
D. Excessive granulation tissue
Correct Answer: B. Purple discoloration