Practical Pharmacology Questions — Inspired by Brody's Human Pharmacology

Pharmacology test bank

1. The study of drug absorption, distribution, metabolism, and excretion is
known as (LO 1.1)
A. pharmacotherapeutics
B. pharmacodynamics
C. pharmacokinetics
D. pharmacy
E. posology
c
2. The medical situation when a particular drug should not be administered
is referred to as (LO 1.2)
A. side effect
B. adverse effect
C. drug allergy
D. contraindication
E. antagonism
d
3. An unusual or unexpected drug reaction by an individual is known as
(LO 1.5)
A. toxic effect
B. antagonism
C. idiosyncrasy
D. side effect
E.drug allergy
c
The proprietary drug name supplied by a pharmaceutical
company is also referred to as the (LO 1.6)
A. generic name
B. over-the-counter name
C. trade name
D. chemical name
E. none of these
c
The time from drug administration to the first observable drug effect is
known as the (LO 1.4)
A. duration of action
B. onset of action
C. ceiling effect

,D. maximal response
E. ceiling effect
b
A drug that has the potential for abuse and is regulated by the Drug
Enforcement Agency is classified as a (LO 1.7)
A. poison
B. OTC drug
C. prescription drug
D. controlled substance
E. nonproprietary drug
d
Select the term that relates to the amount of drug administered to produce
a therapeutic effect. (LO 1.1)
A. posology
B. toxicology
C. pharmacodynamics
D. pharmacotherapeutics
E. pharmacy
a
A medication that does not require a physician's service to obtain is
referred to as (LO 1.6)
A. trade
B. nonproprietary
C. nonprescription
D. brand
E.generic
c
Which of the following could be categorized as an adverse reaction? (LO
1.5)
A. idiosyncrasy
B. drug allergy
C. teratogenicity
D. carcinogenicity
E.all of these
e
The time a drug continues to produce its effect is its (LO 1.4) A. ED50
B. maximal response
C. ceiling effect
D. onset of action
E.duration of action @

,e
The drug administration route demonstrating the slowest onset of action is
(LO 2.1)
A. inhalation
B. transdermal
C. intramuscular
D. sublingual
E. intravenous
b
For drugs to cross the blood-brain barrier, they must be (LO
2.2)
A. ionized
B. positively charged
C. water soluble
D. lipid soluble
E. negatively charged
d
First-pass metabolism refers to the metabolism of drugs in the (LO 2.2)
A. kidney
B. blood vessels
C. liver
D. heart
E.adipose tissue
c
Drug X has a half-life of 6 hours. How much drug is left in the body 18
hours after an IV injection of 1200 mg? (LO 2.3)
A. 75 mg
B. 150 mg
C. 300 mg
D. 600 mg
E. 900 mg
b
Drugs that have demonstrated teratogenic effects in women are classified
as Pregnancy Category (LO 2.5)
A. B
B. C
C. D
D. X
E. NR @
d

, When a drug increases the rate of drug metabolism of other drugs, the
process is termed (LO 2.2)
A. first-pass metabolism
B. enzyme induction
C. enzyme inhibition
D. enterohepatic cycling
E. microsomal inhibition
b
The rate of drug absorption would be increased by which of the following?
(LO 2.2) A. drug ionization
B. water solubility
C. positively charged drug
D. negatively charged drug
E. lipid solubility
e
Which factor of individual variation is dependent upon the
patient's attitude toward treatment? (LO 2.4)
A. weight
B. age
C. genetic variation
D. placebo effect
E. gender
d
Which FDA pregnancy category would appear to be the safest for a
developing fetus? (LO 2.5)
A. Category A
B. Category B
C. Category C
D. Category D
E. Category X
a
Which type of drug interaction describes a combined effect equal to the
sum of the individual effects of two drugs? (LO 2.6)
A. summation
B. synergism
C. antagonism
D. incompatibility
E.none of these
a