COMPLETE 500 QUESTIONS ACROSS TWO
VERSIONS GUARANTEED ACCURATE
ANSWERS GRADED A+
⩥ Breast: What are contraindications to BCT (lumpectomy) in stage I
breast cancer (and what specifically is not)? Answer: 1) prior irradiation;
2) pos margins;
3) inflammatory;
4) pregnancy (unless 3rd trimester)
⩥ Breast: what are the axillary node levels (1-3, and one more
category)? Answer: 1 - lateral to pec minor;
2 - beneath pec minor;
3 - medial to pec minor;
Rotter's Nodes - between pec major and pec minor
⩥ Breast: when is SNLB indicated (size, nodes, tumor status, metastatic
risk)>? Answer: >1 cm, no positive nodes (obviously), primary tumor
present, low risk of axillary mets,
⩥ Breast: what do you do if you can't find radiotracer dye in SNLB?
Answer: have to do formal ALND
,⩥ Breast: what is treatment for DCIS in male/female? Answer: female --
BCT + xrt OR mastectomy; male -- mastectomy
⩥ Breast: what is not needed for patient with negative SLNB? Answer:
ALND -- just do BCT or mastectomy depending on tumor is fine
⩥ Breast: what patient would get only mastectomy/BCT + tamoxifen for
5 years (4 characteristics)? Answer: negative SLN, old, ER+, and tumor
<2 cm
⩥ Breast: what patient would get mastectomy/BCT + tamoxifen for 5
years plus chemo (4 characteristics)? Answer: negative SLN, young,
ER+, and tumor >1cm
⩥ Breast: what are 3 chemo agents used for breast CA typically?
Answer: 1) adriamycin; 2) cyclophosphamide; 3) taxol
⩥ Breast: what patient would get mastectomy/BCT + chemo (no
tamoxifen)? Answer: negative SLN, ER-
⩥ Breast: what is main SE of taxol? Answer: taxol - neuropathy
,⩥ Breast: what is main SE of adriamycin (doxorubacin)? Answer:
cardiomyopathy
⩥ Breast: what is treatment for inflammatory breast cancer (in order)?
Answer: neoadjuvant chemo, then mastectomy (mod radical), then XRT
⩥ Breast: what options are available for breast mass post neoadjuvant
therapy? Answer: same as de novo breast cancer -- BCT or mastectomy -
- if tumor shrunk and now amenable to BCT, that's fine, even if it was
big before and needed mastectomy based on size
⩥ Breast: LCIS -- who primarily gets this, what is most important
characteristic, what % get cancer, where, and what type? Answer: - pre-
menopausal
- NOT premalignant itself
- 30% lifetime risk
70% ductal CA
⩥ Breast: LCIS -- what % have synchronous cancer? Answer: 5%
⩥ Breast: LCIS -- what is treatment (4 possibility, 2 things not needed
ever)? Answer: 1) Need to resect the lesion but do not need neg margins
2) nothing and careful F/U
3) Hormonal therapy
, -(pre-meno: tamoxifen; Post-meno: raloxifene)
4) bilateral subcutaneous mastectomy (no ALND)
⩥ Breast: What are the benign proliferative breast lesions that have
increased risk of CA? (3)
Tx? Answer: - LCIS
- Atypical ductal hyperplasia
- atypical lobular hyperplasia
Tx: resect the lesion w/ (-) margins
⩥ Breast: for atypical ductal hyperplasia; atypical lobular hyperplasia;
LCIS, how are these characterized and what treatment should be
considered? Answer: benign proliferative dz. Incr risk of CA.
Need to resect - don't need (-) margins
Can give hormone therapy
- pre-meno: tamoxifen
- post-meno: raloxifene
Bilateral total mastectomy (no ALND)
⩥ Liver: amebic abscess - how does organism enter, what organism is it
Answer: through portal system