Fast-Revision Nursing MCQ Test Bank — Study Guide & Practice Questions

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




1. A 68-year-old patient with multiple chronic illnesses asks
whether a new diagnostic test with moderate sensitivity
but low specificity should be used for screening. Which
principle of clinical decision-making should guide the
nurse’s response?
A. Use any available test when the patient requests it.
B. Recommend testing only if results will change
management. ✓
C. Always choose tests with highest sensitivity regardless
of specificity.
D. Order tests to provide reassurance even if management
won’t change.
Rationale: Tests should be used when results will influence
diagnosis or treatment decisions; avoid tests that lead to
unnecessary interventions.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 4: Decision-Making in Clinical Medicine.

, 2. A nurse preparing a community vaccination education
session encounters caregivers expressing safety concerns
about vaccine components. Which nursing approach best
addresses vaccine hesitancy?
A. Dismiss concerns as misinformation.
B. Provide empathetic listening, correct
misunderstandings, and present clear benefits/risks. ✓
C. Insist vaccination without discussion.
D. Offer only written material without discussion.
Rationale: Empathetic dialogue and clear, evidence-based
explanation of benefits and risks improves acceptance and
trust.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 3: Vaccine Opposition and Hesitancy.


3. A hospitalized patient has an advanced directive stating
refusal of life-sustaining therapies. The family requests full
code status. What is the nurse’s most appropriate action?
A. Follow the family’s request over the directive.
B. Respect and implement the patient’s documented
wishes. ✓
C. Delay action until the physician decides.
D. Remove the directive because family disagrees.

, Rationale: Patient autonomy and legally documented advance
directives take precedence; nurses advocate for patient wishes.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 12: Ethical Issues in Clinical Medicine.


4. During a busy shift, a nurse notices a colleague showing
signs of burnout (detachment, reduced performance).
According to best practices for clinician well-being, the
nurse should:
A. Ignore it; personal issues are private.
B. Report concerns and encourage use of institutional
support resources. ✓
C. Publicly confront the colleague.
D. Recommend immediate termination.
Rationale: Early recognition and referral to support resources
protect patient safety and clinician health.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 9: Physician Well-Being.


5. A middle-aged patient asks what “precision medicine”
means for their treatment. The nurse’s best explanation is:
A. Treatments chosen by chance.
B. Therapies tailored to individual genetic, environmental,
and lifestyle factors. ✓
C. One drug that works for all patients with the same