3 functions of the spleen 1.filters blood and removes old and damaged RBCs
2.controls level of blood cells (white, red, and platelets)
3.contains WBCs
3 major crises seen in children with sickle cell aplastic crisis
anemia splenic sequestration
vast-occlusive crisis (VOC)
3 procedure preparation topics pain management
health promotion
family education
3 sections of biotherapy and their definitions -Retooling- development of antibodies that are tumor specific and
promote death of the cancer cells
-molecular targeting - interference with metabolic pathways in tumor
cells
-gene therapy - area of research
4 Main components of blood composition RBC, WBC, platelets, plasma
,4 patients come into the transfusion center. 1. whole blood
Which patients get what transfusion based on
their presenting problems? 2. packed red blood cells
1.Accute hemorrhage and trauma 3. fresh frozen plasma
2. Severe anemia, thalassemia, sickle cell disease 4. platelets
3. Hemophilia
4.Thrombocytopenia
4 types of anemia Iron deficiency
lead poisoning
sickle cell
B-thalassemia
Abdominal and GU complications of sickle cell abdominal pain and genitourinary disfunction (dilute urine)
,An adolescent is beginning chemotherapy -Bone marrow suppression - Nadir is the time of greatest bone
treatments and is wanting to know all the side marrow suppression
effects that they will experience. What are the -Nausea and vomiting - treated with antiemetics
side effects the nurse will tell the patient? -Anorexia and weight loss - nutritious food and dietary supplements
-Oral ulcers (oral mucositis) - antifungal treatment and lidocaine
-Constipation - stool softeners, increase fluids, encourage fiberous
foods
-Pain - acetaminophen, opiates, and antidepressants. Avoid NSAIDS
due to bleeding risk
-Alopecia - patient/parent education (hair return after 3-6 months and
can look different)
Adult vs. Pediatric Cancers Adults: cancer is often the result of dietary issues or prolonged
exposure to toxins from bad habits --> can be prevented through
lifestyle changes
Children: cancer is usually embryonic or oncogenic (cellular change
that allows unregulated genetic activity and tumor growth) --> lifestyle
changes have little effect on the incidence of childhood cancer
, AHRQ Pediatric Quality indicators: central venous Description: (CLABSI) Central venous catheter related bloodstream
catheter -related blood stream infection rate infections (secondary diagnosis) per 1000 medical and surgical
discharges for patients ages 17 years and younger
Description and exclusions
Excludes cases with a principal diagnosis of a CLABSI present on
admission, normal newborns, neonates with birthweight of less than
500 grams, cases with stays less than 2 days, and OB cases
AML is proliferation of what cells? and give info proliferation of myeloblastic cell
about that cell.
myeloblasts are he earliest identifiable cells that give rise to
granulocytes. They are normally found in blood forming tissue of
bone marrow but may appear in blood in a variety of diseases, most
notably AML
Besides surgery, what are the other treatment -Radiation - may use to shrink the tumor and then surgery to remove
methods for a brain tumor? (not for children under 3)
- chemotherapy - increase dose to cross the blood brain barrier
- Hematopoietic stem cell transplant
Cancer/ malignant cells flourish in what kind of antagonistic
environment?
2.controls level of blood cells (white, red, and platelets)
3.contains WBCs
3 major crises seen in children with sickle cell aplastic crisis
anemia splenic sequestration
vast-occlusive crisis (VOC)
3 procedure preparation topics pain management
health promotion
family education
3 sections of biotherapy and their definitions -Retooling- development of antibodies that are tumor specific and
promote death of the cancer cells
-molecular targeting - interference with metabolic pathways in tumor
cells
-gene therapy - area of research
4 Main components of blood composition RBC, WBC, platelets, plasma
,4 patients come into the transfusion center. 1. whole blood
Which patients get what transfusion based on
their presenting problems? 2. packed red blood cells
1.Accute hemorrhage and trauma 3. fresh frozen plasma
2. Severe anemia, thalassemia, sickle cell disease 4. platelets
3. Hemophilia
4.Thrombocytopenia
4 types of anemia Iron deficiency
lead poisoning
sickle cell
B-thalassemia
Abdominal and GU complications of sickle cell abdominal pain and genitourinary disfunction (dilute urine)
,An adolescent is beginning chemotherapy -Bone marrow suppression - Nadir is the time of greatest bone
treatments and is wanting to know all the side marrow suppression
effects that they will experience. What are the -Nausea and vomiting - treated with antiemetics
side effects the nurse will tell the patient? -Anorexia and weight loss - nutritious food and dietary supplements
-Oral ulcers (oral mucositis) - antifungal treatment and lidocaine
-Constipation - stool softeners, increase fluids, encourage fiberous
foods
-Pain - acetaminophen, opiates, and antidepressants. Avoid NSAIDS
due to bleeding risk
-Alopecia - patient/parent education (hair return after 3-6 months and
can look different)
Adult vs. Pediatric Cancers Adults: cancer is often the result of dietary issues or prolonged
exposure to toxins from bad habits --> can be prevented through
lifestyle changes
Children: cancer is usually embryonic or oncogenic (cellular change
that allows unregulated genetic activity and tumor growth) --> lifestyle
changes have little effect on the incidence of childhood cancer
, AHRQ Pediatric Quality indicators: central venous Description: (CLABSI) Central venous catheter related bloodstream
catheter -related blood stream infection rate infections (secondary diagnosis) per 1000 medical and surgical
discharges for patients ages 17 years and younger
Description and exclusions
Excludes cases with a principal diagnosis of a CLABSI present on
admission, normal newborns, neonates with birthweight of less than
500 grams, cases with stays less than 2 days, and OB cases
AML is proliferation of what cells? and give info proliferation of myeloblastic cell
about that cell.
myeloblasts are he earliest identifiable cells that give rise to
granulocytes. They are normally found in blood forming tissue of
bone marrow but may appear in blood in a variety of diseases, most
notably AML
Besides surgery, what are the other treatment -Radiation - may use to shrink the tumor and then surgery to remove
methods for a brain tumor? (not for children under 3)
- chemotherapy - increase dose to cross the blood brain barrier
- Hematopoietic stem cell transplant
Cancer/ malignant cells flourish in what kind of antagonistic
environment?
